SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o55'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2o55 PUTATIVE
GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Galdieria
sulphuraria) 		3 / 3 ASP A 147
TYR A 148
LYS A 160
 None
 1.13A 2othA-2o55A:
undetectable		 2othA-2o55A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 2o55 PUTATIVE
GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Galdieria
sulphuraria) 		3 / 3 GLU A 116
HIS A  14
GLU A  43
 SO4  A   2 (-4.1A)
SO4  A   1 (-3.9A)
None
 0.82A 2x45B-2o55A:
undetectable		 2x45B-2o55A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 2o55 PUTATIVE
GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Galdieria
sulphuraria) 		3 / 3 GLU A 116
HIS A  14
GLU A  43
 SO4  A   2 (-4.1A)
SO4  A   1 (-3.9A)
None
 0.83A 2x45C-2o55A:
undetectable		 2x45C-2o55A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 2o55 PUTATIVE
GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Galdieria
sulphuraria) 		5 / 12 LEU A 113
THR A  44
PHE A 101
LEU A 133
ILE A  54
 None
 1.46A 2ydoA-2o55A:
undetectable		 2ydoA-2o55A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2o55 PUTATIVE
GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Galdieria
sulphuraria) 		3 / 3 SER A  30
GLY A  18
GLY A  13
 None
 0.48A 3bogA-2o55A:
undetectable
3bogC-2o55A:
undetectable		 3bogA-2o55A:
undetectable
3bogC-2o55A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_B_P77B204_1
(PROTEIN S100-A4)		 2o55 PUTATIVE
GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Galdieria
sulphuraria) 		4 / 6 MET A  35
CYH A  34
GLU A  36
PHE A  31
 None
 1.49A 3m0wB-2o55A:
undetectable
3m0wJ-2o55A:
undetectable		 3m0wB-2o55A:
16.12
3m0wJ-2o55A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 2o55 PUTATIVE
GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Galdieria
sulphuraria) 		5 / 12 PHE A 101
ILE A  54
LEU A  56
LEU A 111
LEU A 113
 None
 1.39A 4qynB-2o55A:
undetectable		 4qynB-2o55A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 2o55 PUTATIVE
GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Galdieria
sulphuraria) 		5 / 12 LEU A 100
THR A  44
ARG A  15
ILE A  42
GLY A  16
 None
None
SO4  A   1 (-3.8A)
None
None
 1.02A 5ifuA-2o55A:
undetectable		 5ifuA-2o55A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 2o55 PUTATIVE
GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Galdieria
sulphuraria) 		5 / 9 LEU A 100
THR A  44
ARG A  15
ILE A  42
GLY A  16
 None
None
SO4  A   1 (-3.8A)
None
None
 1.04A 5ifuB-2o55A:
undetectable		 5ifuB-2o55A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 2o55 PUTATIVE
GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Galdieria
sulphuraria) 		5 / 9 LEU A 238
VAL A 219
PHE A 254
LEU A 251
ILE A 243
 None
 1.40A 6fdyU-2o55A:
undetectable		 6fdyU-2o55A:
22.37