SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o57'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 2o57 PUTATIVE SARCOSINE
DIMETHYLGLYCINE
METHYLTRANSFERASE
(Galdieria
sulphuraria) 		3 / 3 ASP A  88
HIS A  46
ASP A  67
 None
 0.86A 1nw5A-2o57A:
4.4		 1nw5A-2o57A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 2o57 PUTATIVE SARCOSINE
DIMETHYLGLYCINE
METHYLTRANSFERASE
(Galdieria
sulphuraria) 		5 / 12 GLY A  90
GLY A  92
ILE A 113
ALA A 114
GLN A 157
 None
 0.95A 1ri4A-2o57A:
16.3		 1ri4A-2o57A:
25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_E_AG2E671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 2o57 PUTATIVE SARCOSINE
DIMETHYLGLYCINE
METHYLTRANSFERASE
(Galdieria
sulphuraria) 		4 / 7 ILE A 206
LEU A 238
LEU A 272
GLY A 271
 None
 0.93A 2qqcD-2o57A:
undetectable
2qqcE-2o57A:
undetectable		 2qqcD-2o57A:
17.06
2qqcE-2o57A:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 2o57 PUTATIVE SARCOSINE
DIMETHYLGLYCINE
METHYLTRANSFERASE
(Galdieria
sulphuraria) 		5 / 12 GLY A  90
GLY A  92
LEU A 111
SER A 140
ALA A 159
 None
 0.65A 3kkzA-2o57A:
23.9		 3kkzA-2o57A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 2o57 PUTATIVE SARCOSINE
DIMETHYLGLYCINE
METHYLTRANSFERASE
(Galdieria
sulphuraria) 		5 / 12 GLY A  90
GLY A  92
ASP A 158
ALA A 159
HIS A 162
 None
 0.63A 3uj7B-2o57A:
27.3		 3uj7B-2o57A:
28.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 2o57 PUTATIVE SARCOSINE
DIMETHYLGLYCINE
METHYLTRANSFERASE
(Galdieria
sulphuraria) 		5 / 12 GLY A  90
GLY A  92
ILE A 113
ASP A 158
ALA A 159
 None
 0.41A 3uj7B-2o57A:
27.3		 3uj7B-2o57A:
28.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 2o57 PUTATIVE SARCOSINE
DIMETHYLGLYCINE
METHYLTRANSFERASE
(Galdieria
sulphuraria) 		4 / 6 ASP A  67
GLU A  43
GLY A  95
LEU A  64
 None
 1.05A 3w9tB-2o57A:
undetectable		 3w9tB-2o57A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_1
(HIV-1 PROTEASE)		 2o57 PUTATIVE SARCOSINE
DIMETHYLGLYCINE
METHYLTRANSFERASE
(Galdieria
sulphuraria) 		4 / 7 LEU A 130
ALA A  97
ASP A  88
ILE A  45
 None
 0.90A 4eyrA-2o57A:
undetectable		 4eyrA-2o57A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2o57 PUTATIVE SARCOSINE
DIMETHYLGLYCINE
METHYLTRANSFERASE
(Galdieria
sulphuraria) 		4 / 6 GLY A 288
GLY A 287
MET A 189
ILE A 185
 None
 0.88A 4fglD-2o57A:
undetectable		 4fglD-2o57A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2o57 PUTATIVE SARCOSINE
DIMETHYLGLYCINE
METHYLTRANSFERASE
(Galdieria
sulphuraria) 		3 / 3 ASP A  31
ASN A 267
SER A 258
 None
 0.77A 4obwA-2o57A:
17.1		 4obwA-2o57A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 2o57 PUTATIVE SARCOSINE
DIMETHYLGLYCINE
METHYLTRANSFERASE
(Galdieria
sulphuraria) 		3 / 3 SER A  63
ASP A  28
ASP A 158
 None
 0.77A 4uckA-2o57A:
5.6		 4uckA-2o57A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 2o57 PUTATIVE SARCOSINE
DIMETHYLGLYCINE
METHYLTRANSFERASE
(Galdieria
sulphuraria) 		4 / 7 GLN A 117
TYR A  93
ASP A  30
TYR A  27
 None
 1.26A 5vlmG-2o57A:
undetectable		 5vlmG-2o57A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 2o57 PUTATIVE SARCOSINE
DIMETHYLGLYCINE
METHYLTRANSFERASE
(Galdieria
sulphuraria) 		5 / 12 GLY A  90
GLY A  92
ILE A 113
SER A 140
HIS A 162
 None
 0.70A 5wy0A-2o57A:
13.0		 5wy0A-2o57A:
22.01