SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o5a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 2o5a BH1328 PROTEIN
(Bacillus
halodurans) 		4 / 6 LEU A   6
ASP A  81
LEU A  79
HIS A  88
 None
 1.22A 3bj8C-2o5aA:
undetectable
3bj8D-2o5aA:
undetectable		 3bj8C-2o5aA:
18.97
3bj8D-2o5aA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 2o5a BH1328 PROTEIN
(Bacillus
halodurans) 		5 / 12 LEU A  55
GLN A  60
ILE A  51
VAL A  78
VAL A  89
 None
 1.13A 5dpdB-2o5aA:
undetectable		 5dpdB-2o5aA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2o5a BH1328 PROTEIN
(Bacillus
halodurans) 		3 / 3 ALA A  96
ASN A  99
LEU A 100
 None
 0.43A 5i1nC-2o5aA:
undetectable		 5i1nC-2o5aA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2o5a BH1328 PROTEIN
(Bacillus
halodurans) 		3 / 3 ALA A  96
ASN A  99
LEU A 100
 None
 0.40A 5i1oC-2o5aA:
undetectable		 5i1oC-2o5aA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2o5a BH1328 PROTEIN
(Bacillus
halodurans) 		3 / 3 ALA A  96
ASN A  99
LEU A 100
 None
 0.43A 5i1pD-2o5aA:
undetectable		 5i1pD-2o5aA:
23.33