SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o5n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 2o5n MUHV1GPM153
(Murid
betaherpesvirus
1) 		3 / 3 GLU A  21
ILE A  23
ARG A 113
 None
 0.79A 1cd2A-2o5nA:
undetectable		 1cd2A-2o5nA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 2o5n MUHV1GPM153
(Murid
betaherpesvirus
1) 		4 / 5 GLY A  35
THR A  34
GLY A  53
GLU A  36
 None
 1.12A 4v20A-2o5nA:
undetectable		 4v20A-2o5nA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QJQ_A_K1SA304_0
(ADP-SUGAR
PYROPHOSPHATASE)		 2o5n MUHV1GPM153
(Murid
betaherpesvirus
1) 		4 / 5 TRP A 114
GLU A 135
VAL A 132
LEU A 144
 None
 1.21A 5qjqA-2o5nA:
0.0
5qjqB-2o5nA:
0.0		 5qjqA-2o5nA:
23.45
5qjqB-2o5nA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QJQ_B_K1SB304_0
(ADP-SUGAR
PYROPHOSPHATASE)		 2o5n MUHV1GPM153
(Murid
betaherpesvirus
1) 		4 / 5 VAL A 132
LEU A 144
TRP A 114
GLU A 135
 None
 1.22A 5qjqA-2o5nA:
0.0
5qjqB-2o5nA:
0.0		 5qjqA-2o5nA:
23.45
5qjqB-2o5nA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QJQ_C_K1SC305_0
(ADP-SUGAR
PYROPHOSPHATASE)		 2o5n MUHV1GPM153
(Murid
betaherpesvirus
1) 		4 / 5 TRP A 114
GLU A 135
VAL A 132
LEU A 144
 None
 1.26A 5qjqC-2o5nA:
0.0
5qjqD-2o5nA:
0.0		 5qjqC-2o5nA:
23.45
5qjqD-2o5nA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 2o5n MUHV1GPM153
(Murid
betaherpesvirus
1) 		4 / 7 ASP A 178
GLY A  11
SER A 261
GLY A 262
 None
 0.95A 6ekzA-2o5nA:
undetectable		 6ekzA-2o5nA:
15.03