SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o62'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 2o62 HYPOTHETICAL PROTEIN
(Nostoc
punctiforme) 		5 / 12 PHE A  97
LEU A 239
ALA A 236
ARG A 247
LEU A 261
 None
 1.25A 1cbrA-2o62A:
8.3		 1cbrA-2o62A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 2o62 HYPOTHETICAL PROTEIN
(Nostoc
punctiforme) 		5 / 12 PHE A  97
LEU A 239
ALA A 236
ARG A 247
LEU A 261
 None
 1.25A 1cbrB-2o62A:
8.3		 1cbrB-2o62A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2o62 HYPOTHETICAL PROTEIN
(Nostoc
punctiforme) 		4 / 7 LEU A 137
LEU A 213
GLU A 266
ARG A 247
 None
 1.06A 2jn3A-2o62A:
6.2		 2jn3A-2o62A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 2o62 HYPOTHETICAL PROTEIN
(Nostoc
punctiforme) 		4 / 6 ILE A 194
ARG A 176
LEU A 171
ASP A 172
 None
GOL  A 273 ( 4.8A)
None
None
 1.08A 2rlfA-2o62A:
undetectable
2rlfD-2o62A:
undetectable		 2rlfA-2o62A:
11.06
2rlfD-2o62A:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 2o62 HYPOTHETICAL PROTEIN
(Nostoc
punctiforme) 		3 / 3 PHE A   8
ASN A  11
PHE A  78
 None
 1.00A 2zbuD-2o62A:
undetectable		 2zbuD-2o62A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2o62 HYPOTHETICAL PROTEIN
(Nostoc
punctiforme) 		5 / 12 LEU A  51
LEU A  38
PHE A  19
ILE A 122
GLY A  17
 None
 1.14A 3kk6B-2o62A:
undetectable		 3kk6B-2o62A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 2o62 HYPOTHETICAL PROTEIN
(Nostoc
punctiforme) 		4 / 7 TRP A 238
ILE A 122
THR A 120
VAL A  98
 None
 1.29A 4iarA-2o62A:
undetectable		 4iarA-2o62A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 2o62 HYPOTHETICAL PROTEIN
(Nostoc
punctiforme) 		5 / 12 PHE A  78
PHE A  72
LEU A  70
GLY A  13
LEU A  49
 None
 1.18A 4kykA-2o62A:
undetectable
4kykB-2o62A:
undetectable		 4kykA-2o62A:
21.26
4kykB-2o62A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)		 2o62 HYPOTHETICAL PROTEIN
(Nostoc
punctiforme) 		5 / 12 VAL A  66
PHE A  63
TRP A  15
LEU A 126
LEU A   9
 None
 1.41A 5fctB-2o62A:
undetectable		 5fctB-2o62A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 2o62 HYPOTHETICAL PROTEIN
(Nostoc
punctiforme) 		5 / 12 LEU A 116
ILE A 198
PHE A 110
GLY A  26
LEU A 106
 GOL  A 277 (-4.4A)
None
None
None
None
 1.07A 5fsaA-2o62A:
undetectable		 5fsaA-2o62A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_A_ASCA502_0
(OS09G0567300 PROTEIN)		 2o62 HYPOTHETICAL PROTEIN
(Nostoc
punctiforme) 		4 / 5 GLU A 133
PRO A 215
ARG A 123
PHE A  22
 None
 1.38A 5jcnA-2o62A:
1.0		 5jcnA-2o62A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 2o62 HYPOTHETICAL PROTEIN
(Nostoc
punctiforme) 		4 / 6 GLU A 133
PRO A 215
ARG A 123
PHE A  22
 None
 1.37A 5jcnB-2o62A:
undetectable		 5jcnB-2o62A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 2o62 HYPOTHETICAL PROTEIN
(Nostoc
punctiforme) 		4 / 8 LEU A 167
LEU A 239
ILE A 198
GLN A 210
 GOL  A 274 (-4.7A)
None
None
GOL  A 277 (-3.2A)
 0.99A 5ljbA-2o62A:
8.2		 5ljbA-2o62A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)		 2o62 HYPOTHETICAL PROTEIN
(Nostoc
punctiforme) 		5 / 11 PHE A 233
TRP A 258
LEU A  70
GLY A  93
ALA A  96
 None
 1.05A 6r2eF-2o62A:
undetectable		 6r2eF-2o62A:
23.12