SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o6f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BMC_A_FOLA270_0 (PTERIDINE REDUCTASE)	2o6f	34 KDA MEMBRANE ANTIGEN (Treponema pallidum)	5 / 11	PHE A 131 PHE A 178 TYR A 138 VAL A 112 GLU A 72	None	1.31A	3bmcA-2o6fA: undetectable	3bmcA-2o6fA: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BMC_D_FOLD270_0 (PTERIDINE REDUCTASE)	2o6f	34 KDA MEMBRANE ANTIGEN (Treponema pallidum)	5 / 12	PHE A 131 PHE A 178 TYR A 138 VAL A 112 GLU A 72	None	1.32A	3bmcD-2o6fA: undetectable	3bmcD-2o6fA: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RV5_A_DXCA91_0 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	2o6f	34 KDA MEMBRANE ANTIGEN (Treponema pallidum)	3 / 3	PHE A 131 GLN A 61 PHE A 178	None	0.59A	3rv5A-2o6fA: undetectable	3rv5A-2o6fA: 19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XMF_A_HSMA202_1 (NITROPHORIN-7)	2o6f	34 KDA MEMBRANE ANTIGEN (Treponema pallidum)	3 / 3	ASP A 68 LEU A 135 GLY A 134	EDO A 401 (-2.8A) None None	0.47A	4xmfA-2o6fA: undetectable	4xmfA-2o6fA: 18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEH_A_RPTA601_1 (SCAFFOLD PROTEIN D13)	2o6f	34 KDA MEMBRANE ANTIGEN (Treponema pallidum)	5 / 10	GLN A 61 GLU A 30 PHE A 49 PHE A 114 PHE A 178	None	1.41A	6behA-2o6fA: 1.9 6behB-2o6fA: 0.2 6behC-2o6fA: 2.1	6behA-2o6fA: 14.83 6behB-2o6fA: 14.83 6behC-2o6fA: 14.83

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3BMC_A_FOLA270_0","PTERIDINE REDUCTASE","2o6f","34 KDA MEMBRANE ANTIGEN","Treponema pallidum",5,"PHE A 131;PHE A 178;TYR A 138;VAL A 112;GLU A  72","None","1.31A","3bmcA-2o6fA:undetectable","3bmcA-2o6fA:20.74"],["3BMC_D_FOLD270_0","PTERIDINE REDUCTASE","2o6f","34 KDA MEMBRANE ANTIGEN","Treponema pallidum",5,"PHE A 131;PHE A 178;TYR A 138;VAL A 112;GLU A  72","None","1.32A","3bmcD-2o6fA:undetectable","3bmcD-2o6fA:20.74"],["3RV5_A_DXCA91_0","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","2o6f","34 KDA MEMBRANE ANTIGEN","Treponema pallidum",3,"PHE A 131;GLN A  61;PHE A 178","None","0.59A","3rv5A-2o6fA:undetectable","3rv5A-2o6fA:19.67"],["4XMF_A_HSMA202_1","NITROPHORIN-7","2o6f","34 KDA MEMBRANE ANTIGEN","Treponema pallidum",3,"ASP A  68;LEU A 135;GLY A 134","EDO A 401 (-2.8A);None;None","0.47A","4xmfA-2o6fA:undetectable","4xmfA-2o6fA:18.05"],["6BEH_A_RPTA601_1","SCAFFOLD PROTEIN D13;SCAFFOLD PROTEIN D13;SCAFFOLD PROTEIN D13","2o6f","34 KDA MEMBRANE ANTIGEN","Treponema pallidum",5,"GLN A  61;GLU A  30;PHE A  49;PHE A 114;PHE A 178","None","1.41A","6behA-2o6fA:1.9;6behB-2o6fA:0.2;6behC-2o6fA:2.1","6behA-2o6fA:14.83;6behB-2o6fA:14.83;6behC-2o6fA:14.83"]]