SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o6p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QT2_A_RAPA202_1 (FK506-BINDING PROTEIN (FKBP)-TYPE PEPTIDYL-PROPYL ISOMERASE)	2o6p	IRON-REGULATED SURFACE DETERMINANT PROTEIN C (Staphylococcus aureus)	5 / 10	TYR A 36 PHE A 142 GLU A 84 ILE A 138 ILE A 78	None None None HEM A 190 (-4.7A) HEM A 190 ( 4.7A)	1.39A	4qt2A-2o6pA: undetectable	4qt2A-2o6pA: 21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QT3_A_RAPA202_1 (FK506-BINDING PROTEIN (FKBP)-TYPE PEPTIDYL-PROPYL ISOMERASE)	2o6p	IRON-REGULATED SURFACE DETERMINANT PROTEIN C (Staphylococcus aureus)	5 / 10	TYR A 36 PHE A 142 GLU A 84 ILE A 138 ILE A 78	None None None HEM A 190 (-4.7A) HEM A 190 ( 4.7A)	1.36A	4qt3A-2o6pA: undetectable	4qt3A-2o6pA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F7L_B_ACTB503_0 (AMINE OXIDASE LKCE)	2o6p	IRON-REGULATED SURFACE DETERMINANT PROTEIN C (Staphylococcus aureus)	3 / 3	VAL A 72 GLU A 99 ILE A 78	None None HEM A 190 ( 4.7A)	0.66A	6f7lB-2o6pA: undetectable	6f7lB-2o6pA: 14.16

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4QT2_A_RAPA202_1","FK506-BINDING PROTEIN (FKBP)-TYPE PEPTIDYL-PROPYL ISOMERASE","2o6p","IRON-REGULATED SURFACE DETERMINANT PROTEIN C","Staphylococcus aureus",5,"TYR A  36;PHE A 142;GLU A  84;ILE A 138;ILE A  78","None;None;None;HEM A 190 (-4.7A);HEM A 190 ( 4.7A)","1.39A","4qt2A-2o6pA:undetectable","4qt2A-2o6pA:21.02"],["4QT3_A_RAPA202_1","FK506-BINDING PROTEIN (FKBP)-TYPE PEPTIDYL-PROPYL ISOMERASE","2o6p","IRON-REGULATED SURFACE DETERMINANT PROTEIN C","Staphylococcus aureus",5,"TYR A  36;PHE A 142;GLU A  84;ILE A 138;ILE A  78","None;None;None;HEM A 190 (-4.7A);HEM A 190 ( 4.7A)","1.36A","4qt3A-2o6pA:undetectable","4qt3A-2o6pA:21.35"],["6F7L_B_ACTB503_0","AMINE OXIDASE LKCE","2o6p","IRON-REGULATED SURFACE DETERMINANT PROTEIN C","Staphylococcus aureus",3,"VAL A  72;GLU A  99;ILE A  78","None;None;HEM A 190 ( 4.7A)","0.66A","6f7lB-2o6pA:undetectable","6f7lB-2o6pA:14.16"]]