SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o6q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 4 VAL A 218
ALA A 222
LEU A 226
PHE A 199
 None
 1.19A 1q97B-2o6qA:
undetectable		 1q97B-2o6qA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		5 / 12 LEU A 160
LEU A 136
LEU A 112
LEU A 146
LEU A 143
 None
 1.04A 1sqnB-2o6qA:
undetectable		 1sqnB-2o6qA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		5 / 9 LEU A 162
LEU A 146
VAL A 126
LEU A 133
PHE A 151
 None
 1.24A 1tbfA-2o6qA:
undetectable		 1tbfA-2o6qA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 8 ILE A  53
PHE A  79
THR A  97
LEU A  95
 None
 0.90A 1v55N-2o6qA:
undetectable
1v55W-2o6qA:
undetectable		 1v55N-2o6qA:
18.29
1v55W-2o6qA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 8 ILE A  53
PHE A  79
THR A  97
LEU A  95
 None
 0.89A 2eijN-2o6qA:
undetectable
2eijW-2o6qA:
undetectable		 2eijN-2o6qA:
18.29
2eijW-2o6qA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 8 ILE A  53
PHE A  79
THR A  97
LEU A  95
 None
 0.91A 2eikN-2o6qA:
undetectable
2eikW-2o6qA:
undetectable		 2eikN-2o6qA:
18.29
2eikW-2o6qA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 8 ILE A  53
PHE A  79
THR A  97
LEU A  95
 None
 0.91A 2eilN-2o6qA:
undetectable
2eilW-2o6qA:
undetectable		 2eilN-2o6qA:
18.29
2eilW-2o6qA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 7 PHE A 175
LEU A 184
LEU A 208
PRO A 219
 None
 1.07A 2jn3A-2o6qA:
undetectable		 2jn3A-2o6qA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		5 / 8 LEU A 232
LEU A 261
ALA A 267
LEU A 277
ALA A 250
 None
 1.01A 2vcvF-2o6qA:
undetectable		 2vcvF-2o6qA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 8 ILE A  53
PHE A  79
THR A  97
LEU A  95
 None
 0.93A 3abkA-2o6qA:
undetectable
3abkJ-2o6qA:
undetectable		 3abkA-2o6qA:
18.29
3abkJ-2o6qA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 8 ILE A  53
PHE A  79
THR A  97
LEU A  95
 None
 0.90A 3ag3N-2o6qA:
undetectable
3ag3W-2o6qA:
undetectable		 3ag3N-2o6qA:
18.29
3ag3W-2o6qA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 8 ILE A  53
PHE A  79
THR A  97
LEU A  95
 None
 0.91A 3asnN-2o6qA:
undetectable
3asnW-2o6qA:
undetectable		 3asnN-2o6qA:
18.29
3asnW-2o6qA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 8 ILE A  53
PHE A  79
THR A  97
LEU A  95
 None
 0.92A 3asoN-2o6qA:
undetectable
3asoW-2o6qA:
undetectable		 3asoN-2o6qA:
18.29
3asoW-2o6qA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 7 VAL A 114
LEU A  95
LEU A 119
ILE A 102
 None
 0.96A 3u5kB-2o6qA:
undetectable		 3u5kB-2o6qA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		3 / 3 ASP A 211
ARG A 185
LYS A 209
 None
 1.04A 3wipG-2o6qA:
undetectable		 3wipG-2o6qA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 5 VAL A 114
LEU A  95
LEU A 119
ILE A 102
 None
 0.97A 4a9jA-2o6qA:
undetectable		 4a9jA-2o6qA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 5 VAL A 114
LEU A  95
LEU A 119
ILE A 102
 None
 0.93A 4a9jB-2o6qA:
undetectable		 4a9jB-2o6qA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 7 TRP A 239
ASN A 213
LEU A 191
PHE A 199
 None
 1.34A 4awuA-2o6qA:
undetectable		 4awuA-2o6qA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 7 ARG A 217
VAL A 276
TRP A 239
GLU A 270
 None
 1.42A 4jseA-2o6qA:
undetectable
4jseB-2o6qA:
undetectable		 4jseA-2o6qA:
20.28
4jseB-2o6qA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 7 GLU A 270
ARG A 217
VAL A 276
TRP A 239
 None
 1.50A 4jseA-2o6qA:
undetectable
4jseB-2o6qA:
undetectable		 4jseA-2o6qA:
20.28
4jseB-2o6qA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		5 / 12 LEU A 191
VAL A 194
ALA A 222
LEU A 181
VAL A 174
 None
 1.26A 4nc3A-2o6qA:
undetectable		 4nc3A-2o6qA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 7 ILE A  53
PHE A  79
THR A  97
LEU A  95
 None
 0.93A 5b3sN-2o6qA:
undetectable
5b3sW-2o6qA:
undetectable		 5b3sN-2o6qA:
18.29
5b3sW-2o6qA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 7 ILE A  53
PHE A  79
THR A  97
LEU A  95
 None
 0.94A 5iy5N-2o6qA:
undetectable
5iy5W-2o6qA:
undetectable		 5iy5N-2o6qA:
18.29
5iy5W-2o6qA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		5 / 8 ALA A 198
LEU A 205
LEU A 226
LEU A 186
LEU A 184
 None
 1.11A 5jqbA-2o6qA:
undetectable
5jqbB-2o6qA:
undetectable		 5jqbA-2o6qA:
23.62
5jqbB-2o6qA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		5 / 12 PHE A 223
GLY A 197
ALA A 198
LEU A 186
LEU A 208
 None
 1.47A 5x23A-2o6qA:
undetectable		 5x23A-2o6qA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 8 ILE A  53
PHE A  79
THR A  97
LEU A  95
 None
 0.92A 5xdxN-2o6qA:
undetectable
5xdxW-2o6qA:
undetectable		 5xdxN-2o6qA:
18.29
5xdxW-2o6qA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		4 / 8 ILE A  53
PHE A  79
THR A  97
LEU A  95
 None
 0.96A 5zcqN-2o6qA:
undetectable
5zcqW-2o6qA:
undetectable		 5zcqN-2o6qA:
18.29
5zcqW-2o6qA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 2o6q VARIABLE LYMPHOCYTE
RECEPTOR A
(Eptatretus
burgeri) 		3 / 3 GLN A  67
TYR A  89
ASN A  91
 None
 1.00A 6dwdC-2o6qA:
undetectable		 6dwdC-2o6qA:
19.28