SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o74'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		4 / 7 THR A  81
PRO A  82
SER A  84
ARG A 161
 None
None
GUN  A1001 (-2.9A)
None
 1.00A 2v2gA-2o74A:
undetectable
2v2gB-2o74A:
undetectable		 2v2gA-2o74A:
23.08
2v2gB-2o74A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		4 / 7 THR A  81
PRO A  82
SER A  84
ARG A 161
 None
None
GUN  A1001 (-2.9A)
None
 0.99A 2v2gA-2o74A:
undetectable
2v2gB-2o74A:
undetectable		 2v2gA-2o74A:
23.08
2v2gB-2o74A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		4 / 7 THR A  81
PRO A  82
SER A  84
ARG A 161
 None
None
GUN  A1001 (-2.9A)
None
 1.00A 2v2gC-2o74A:
undetectable
2v2gD-2o74A:
undetectable		 2v2gC-2o74A:
23.08
2v2gD-2o74A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		4 / 7 THR A  81
PRO A  82
SER A  84
ARG A 161
 None
None
GUN  A1001 (-2.9A)
None
 1.01A 2v2gC-2o74A:
undetectable
2v2gD-2o74A:
undetectable		 2v2gC-2o74A:
23.08
2v2gD-2o74A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		4 / 8 THR A  81
PRO A  82
SER A  84
ARG A 161
 None
None
GUN  A1001 (-2.9A)
None
 0.98A 2v32A-2o74A:
undetectable
2v32B-2o74A:
undetectable		 2v32A-2o74A:
23.08
2v32B-2o74A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		4 / 8 THR A  81
PRO A  82
SER A  84
ARG A 161
 None
None
GUN  A1001 (-2.9A)
None
 1.00A 2v32C-2o74A:
undetectable
2v32D-2o74A:
undetectable		 2v32C-2o74A:
23.08
2v32D-2o74A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		4 / 8 THR A  81
PRO A  82
SER A  84
ARG A 161
 None
None
GUN  A1001 (-2.9A)
None
 0.90A 2v41C-2o74A:
undetectable
2v41D-2o74A:
undetectable		 2v41C-2o74A:
23.08
2v41D-2o74A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		4 / 8 THR A  81
PRO A  82
SER A  84
ARG A 161
 None
None
GUN  A1001 (-2.9A)
None
 1.01A 2v41C-2o74A:
undetectable
2v41D-2o74A:
undetectable		 2v41C-2o74A:
23.08
2v41D-2o74A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		4 / 7 THR A  81
PRO A  82
SER A  84
ARG A 161
 None
None
GUN  A1001 (-2.9A)
None
 0.94A 2v41E-2o74A:
undetectable
2v41F-2o74A:
undetectable		 2v41E-2o74A:
23.08
2v41F-2o74A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		4 / 7 THR A  81
PRO A  82
SER A  84
ARG A 161
 None
None
GUN  A1001 (-2.9A)
None
 0.92A 2v41E-2o74A:
undetectable
2v41F-2o74A:
undetectable		 2v41E-2o74A:
23.08
2v41F-2o74A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		4 / 8 THR A  81
PRO A  82
SER A  84
ARG A 161
 None
None
GUN  A1001 (-2.9A)
None
 0.97A 2v41G-2o74A:
undetectable
2v41H-2o74A:
undetectable		 2v41G-2o74A:
23.08
2v41H-2o74A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		4 / 8 THR A  81
PRO A  82
SER A  84
ARG A 161
 None
None
GUN  A1001 (-2.9A)
None
 1.02A 2v41G-2o74A:
undetectable
2v41H-2o74A:
undetectable		 2v41G-2o74A:
23.08
2v41H-2o74A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		5 / 12 ILE A  28
VAL A   6
ILE A   3
ILE A  48
ALA A  31
 None
 1.24A 3ohtA-2o74A:
undetectable
3ohtB-2o74A:
undetectable		 3ohtA-2o74A:
18.99
3ohtB-2o74A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		4 / 8 ILE A  63
LEU A  55
ILE A  48
PHE A  51
 None
 0.78A 4hb6A-2o74A:
undetectable		 4hb6A-2o74A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		4 / 8 ILE A  63
LEU A  55
ILE A  48
PHE A  51
 None
 0.82A 4hb8A-2o74A:
undetectable		 4hb8A-2o74A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		3 / 3 HIS A  53
SER A  49
LYS A 155
 None
 0.82A 5os7A-2o74A:
undetectable		 5os7A-2o74A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		3 / 3 LEU A 125
LEU A 160
ARG A 124
 None
 0.58A 6fgcA-2o74A:
undetectable		 6fgcA-2o74A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		3 / 3 LEU A 125
LEU A 160
ARG A 124
 None
 0.53A 6fgdA-2o74A:
undetectable		 6fgdA-2o74A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2o74 OHCU DECARBOXYLASE
(Danio
rerio) 		3 / 3 HIS A  53
SER A  49
LYS A 155
 None
 0.82A 6gmdB-2o74A:
undetectable		 6gmdB-2o74A:
19.08