SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2o79 LYSOZYME
(Escherichia
virus
T4) 		5 / 12 ALA A 129
PHE A 153
LEU A 133
ALA A 130
ILE A  78
 None
 1.00A 2aclA-2o79A:
undetectable
2aclE-2o79A:
undetectable		 2aclA-2o79A:
24.26
2aclE-2o79A:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2o79 LYSOZYME
(Escherichia
virus
T4) 		4 / 8 THR A  34
TYR A  25
ILE A  17
SER A  36
 None
 1.07A 2xytE-2o79A:
undetectable		 2xytE-2o79A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2o79 LYSOZYME
(Escherichia
virus
T4) 		4 / 8 THR A  34
TYR A  25
ILE A  17
SER A  36
 None
 1.02A 2xytH-2o79A:
undetectable		 2xytH-2o79A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2o79 LYSOZYME
(Escherichia
virus
T4) 		4 / 7 THR A  34
TYR A  25
ILE A  17
SER A  36
 None
 1.05A 2xytI-2o79A:
undetectable		 2xytI-2o79A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2o79 LYSOZYME
(Escherichia
virus
T4) 		4 / 6 THR A  34
TYR A  25
ILE A  17
SER A  36
 None
 1.26A 3peoG-2o79A:
undetectable		 3peoG-2o79A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 2o79 LYSOZYME
(Escherichia
virus
T4) 		4 / 5 LYS A  48
LEU A  46
GLU A  45
LEU A  33
 None
 1.26A 4k4yA-2o79A:
undetectable		 4k4yA-2o79A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 2o79 LYSOZYME
(Escherichia
virus
T4) 		4 / 4 LYS A  48
LEU A  46
GLU A  45
LEU A  33
 None
 1.28A 4k4yE-2o79A:
undetectable		 4k4yE-2o79A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 2o79 LYSOZYME
(Escherichia
virus
T4) 		4 / 5 LYS A  48
LEU A  46
GLU A  45
LEU A  33
 None
 1.28A 4k4yI-2o79A:
undetectable		 4k4yI-2o79A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2o79 LYSOZYME
(Escherichia
virus
T4) 		4 / 7 THR A  26
TYR A  18
GLU A  11
HIS A  31
 None
None
None
GOL  A 502 (-4.0A)
 1.21A 5ecnA-2o79A:
undetectable		 5ecnA-2o79A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2o79 LYSOZYME
(Escherichia
virus
T4) 		5 / 12 MET A 102
ALA A  74
VAL A 149
LEU A 121
VAL A  87
 None
 1.28A 5tudD-2o79A:
undetectable		 5tudD-2o79A:
17.11