SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o7a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2o7a LYSOZYME
(Escherichia
virus
T4) 		5 / 12 ALA A 129
PHE A 153
LEU A 133
ALA A 130
ILE A  78
 None
 0.94A 2aclA-2o7aA:
undetectable
2aclE-2o7aA:
undetectable		 2aclA-2o7aA:
22.69
2aclE-2o7aA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2o7a LYSOZYME
(Escherichia
virus
T4) 		5 / 12 MET A 102
PHE A 114
ALA A 112
PHE A 153
GLY A  77
 None
 1.44A 3aobC-2o7aA:
undetectable		 3aobC-2o7aA:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2o7a LYSOZYME
(Escherichia
virus
T4) 		5 / 11 ALA A 129
PHE A 153
LEU A 133
ALA A 130
ILE A  78
 None
 1.01A 3fc6A-2o7aA:
undetectable		 3fc6A-2o7aA:
23.14