SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o7r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 8 GLY A  92
GLU A 168
SER A 169
HIS A 306
 4PA  A 369 (-3.5A)
None
4PA  A 369 (-1.8A)
4PA  A 369 (-4.8A)
 0.87A 1ax9A-2o7rA:
18.5		 1ax9A-2o7rA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 8 GLY A  93
GLU A 168
SER A 169
HIS A 306
 4PA  A 369 (-3.6A)
None
4PA  A 369 (-1.8A)
4PA  A 369 (-4.8A)
 0.93A 1ax9A-2o7rA:
18.5		 1ax9A-2o7rA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 12 GLY A  91
GLY A  92
GLY A  93
SER A 169
HIS A 306
 4PA  A 369 ( 3.8A)
4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
4PA  A 369 (-1.8A)
4PA  A 369 (-4.8A)
 0.25A 1dx6A-2o7rA:
19.1		 1dx6A-2o7rA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 8 GLY A  91
GLU A 201
SER A 169
HIS A 306
 4PA  A 369 ( 3.8A)
None
4PA  A 369 (-1.8A)
4PA  A 369 (-4.8A)
 0.91A 1maaD-2o7rA:
18.4		 1maaD-2o7rA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 8 GLY A  92
GLU A 168
SER A 169
HIS A 306
 4PA  A 369 (-3.5A)
None
4PA  A 369 (-1.8A)
4PA  A 369 (-4.8A)
 0.72A 1maaD-2o7rA:
18.4		 1maaD-2o7rA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 8 GLY A  93
GLU A 168
SER A 169
HIS A 306
 4PA  A 369 (-3.6A)
None
4PA  A 369 (-1.8A)
4PA  A 369 (-4.8A)
 0.78A 1maaD-2o7rA:
18.4		 1maaD-2o7rA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 12 GLY A  92
GLY A  93
SER A 169
LEU A  22
HIS A 306
 4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
4PA  A 369 (-1.8A)
None
4PA  A 369 (-4.8A)
 0.87A 1mx1D-2o7rA:
18.3		 1mx1D-2o7rA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 12 GLY A  92
GLY A  93
SER A 169
LEU A  22
HIS A 306
 4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
4PA  A 369 (-1.8A)
None
4PA  A 369 (-4.8A)
 0.87A 1mx1F-2o7rA:
18.3		 1mx1F-2o7rA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		6 / 12 GLY A  91
GLY A  92
GLY A  93
GLU A 168
SER A 169
HIS A 306
 4PA  A 369 ( 3.8A)
4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
None
4PA  A 369 (-1.8A)
4PA  A 369 (-4.8A)
 0.63A 1qtiA-2o7rA:
18.3		 1qtiA-2o7rA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 11 LEU A 197
ILE A 146
LEU A 143
VAL A  68
PHE A  89
 None
 1.36A 1tw4A-2o7rA:
undetectable		 1tw4A-2o7rA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 12 GLY A  91
GLY A  92
GLY A  93
SER A 169
HIS A 306
 4PA  A 369 ( 3.8A)
4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
4PA  A 369 (-1.8A)
4PA  A 369 (-4.8A)
 0.26A 1w6rA-2o7rA:
5.4		 1w6rA-2o7rA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 11 GLY A  92
GLY A  93
GLU A 168
SER A 169
HIS A 306
 4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
None
4PA  A 369 (-1.8A)
4PA  A 369 (-4.8A)
 0.49A 1w76A-2o7rA:
18.2		 1w76A-2o7rA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 10 GLY A  91
GLY A  92
GLU A 168
SER A 169
HIS A 306
 4PA  A 369 ( 3.8A)
4PA  A 369 (-3.5A)
None
4PA  A 369 (-1.8A)
4PA  A 369 (-4.8A)
 0.53A 1w76B-2o7rA:
18.1		 1w76B-2o7rA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 10 GLY A  92
GLY A  93
GLU A 168
SER A 169
HIS A 306
 4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
None
4PA  A 369 (-1.8A)
4PA  A 369 (-4.8A)
 1.18A 1w76B-2o7rA:
18.1		 1w76B-2o7rA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 12 GLU A 168
ALA A 175
GLY A  93
GLY A  91
ILE A 230
 None
None
4PA  A 369 (-3.6A)
4PA  A 369 ( 3.8A)
4PA  A 369 ( 4.7A)
 1.14A 1x1aA-2o7rA:
2.2		 1x1aA-2o7rA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 12 GLY A  92
GLY A  93
SER A 169
LEU A  22
HIS A 306
 4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
4PA  A 369 (-1.8A)
None
4PA  A 369 (-4.8A)
 0.82A 1ya4A-2o7rA:
18.4		 1ya4A-2o7rA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 12 GLY A  92
GLY A  93
SER A 169
LEU A  22
HIS A 306
 4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
4PA  A 369 (-1.8A)
None
4PA  A 369 (-4.8A)
 0.81A 1ya4B-2o7rA:
17.8		 1ya4B-2o7rA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 12 GLY A  92
GLY A  93
SER A 169
LEU A  22
HIS A 306
 4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
4PA  A 369 (-1.8A)
None
4PA  A 369 (-4.8A)
 0.78A 1ya4C-2o7rA:
18.3		 1ya4C-2o7rA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		7 / 8 GLY A  91
GLY A  92
GLY A  93
SER A 169
ALA A 170
LEU A  22
HIS A 306
 4PA  A 369 ( 3.8A)
4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
4PA  A 369 (-1.8A)
4PA  A 369 (-3.2A)
None
4PA  A 369 (-4.8A)
 0.72A 1yajC-2o7rA:
5.7		 1yajC-2o7rA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 8 GLY A  91
GLY A  92
SER A 169
ALA A 170
HIS A 306
 4PA  A 369 ( 3.8A)
4PA  A 369 (-3.5A)
4PA  A 369 (-1.8A)
4PA  A 369 (-3.2A)
4PA  A 369 (-4.8A)
 0.93A 1yajC-2o7rA:
5.7		 1yajC-2o7rA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 9 GLY A  91
GLY A  92
SER A 169
ALA A 170
HIS A 306
 4PA  A 369 ( 3.8A)
4PA  A 369 (-3.5A)
4PA  A 369 (-1.8A)
4PA  A 369 (-3.2A)
4PA  A 369 (-4.8A)
 0.93A 2aceA-2o7rA:
19.2		 2aceA-2o7rA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 9 GLY A  92
GLY A  93
SER A 169
ALA A 170
HIS A 306
 4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
4PA  A 369 (-1.8A)
4PA  A 369 (-3.2A)
4PA  A 369 (-4.8A)
 0.47A 2aceA-2o7rA:
19.2		 2aceA-2o7rA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 7 GLY A  92
GLU A 168
SER A 169
HIS A 306
 4PA  A 369 (-3.5A)
None
4PA  A 369 (-1.8A)
4PA  A 369 (-4.8A)
 0.94A 2ackA-2o7rA:
19.2		 2ackA-2o7rA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 8 GLY A  92
GLY A  93
ALA A 170
HIS A 306
 4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
4PA  A 369 (-3.2A)
4PA  A 369 (-4.8A)
 0.27A 2ha4A-2o7rA:
19.0		 2ha4A-2o7rA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 7 GLY A  92
GLY A  93
ALA A 170
HIS A 306
 4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
4PA  A 369 (-3.2A)
4PA  A 369 (-4.8A)
 0.25A 2ha4B-2o7rA:
19.5		 2ha4B-2o7rA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 12 ILE A 261
VAL A 270
LEU A 285
PHE A 204
ALA A 175
 None
 1.40A 2jj8C-2o7rA:
1.6		 2jj8C-2o7rA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 12 ALA A 139
ALA A 178
ILE A 194
PHE A  89
MET A 111
 None
 1.20A 2nyrA-2o7rA:
2.2		 2nyrA-2o7rA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 12 ASN A 173
LEU A 199
GLY A 172
VAL A  87
ALA A 135
 None
 1.18A 2oz7A-2o7rA:
undetectable		 2oz7A-2o7rA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		3 / 3 GLU A 232
LEU A 229
ASP A 228
 None
 0.44A 3ko0A-2o7rA:
undetectable		 3ko0A-2o7rA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		3 / 3 GLU A 232
LEU A 229
ASP A 228
 None
 0.40A 3ko0T-2o7rA:
undetectable		 3ko0T-2o7rA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 7 GLY A  92
GLY A  93
SER A 169
LEU A 227
HIS A 306
 4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
4PA  A 369 (-1.8A)
None
4PA  A 369 (-4.8A)
 0.50A 3o9mA-2o7rA:
19.4		 3o9mA-2o7rA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 6 GLY A  92
GLY A  93
SER A 169
LEU A 227
HIS A 306
 4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
4PA  A 369 (-1.8A)
None
4PA  A 369 (-4.8A)
 0.53A 3o9mB-2o7rA:
19.4		 3o9mB-2o7rA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 8 GLY A  91
GLY A  92
SER A 169
GLY A 203
ILE A 230
 4PA  A 369 ( 3.8A)
4PA  A 369 (-3.5A)
4PA  A 369 (-1.8A)
4PA  A 369 ( 3.7A)
4PA  A 369 ( 4.7A)
 1.08A 3v1nA-2o7rA:
16.4		 3v1nA-2o7rA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 12 GLY A  91
GLY A  92
GLY A  93
SER A 169
HIS A 306
 4PA  A 369 ( 3.8A)
4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
4PA  A 369 (-1.8A)
4PA  A 369 (-4.8A)
 0.20A 4ey6A-2o7rA:
19.6		 4ey6A-2o7rA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		6 / 12 GLY A  91
GLY A  92
GLY A  93
GLU A 168
SER A 169
HIS A 306
 4PA  A 369 ( 3.8A)
4PA  A 369 (-3.5A)
4PA  A 369 (-3.6A)
None
4PA  A 369 (-1.8A)
4PA  A 369 (-4.8A)
 0.48A 4ey6B-2o7rA:
5.8		 4ey6B-2o7rA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 8 TYR A 136
PHE A  94
GLY A 205
ASN A 173
 None
 0.92A 4qoiA-2o7rA:
2.3
4qoiB-2o7rA:
2.4		 4qoiA-2o7rA:
20.35
4qoiB-2o7rA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 12 GLU A 168
GLY A  91
GLN A 282
GLY A 203
LEU A 222
 None
4PA  A 369 ( 3.8A)
None
4PA  A 369 ( 3.7A)
None
 1.27A 4uilH-2o7rA:
undetectable
4uilL-2o7rA:
undetectable		 4uilH-2o7rA:
20.53
4uilL-2o7rA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 12 GLY A 203
GLU A 201
PHE A  89
ARG A 125
ALA A 127
 4PA  A 369 ( 3.7A)
None
None
None
None
 1.19A 4wcxC-2o7rA:
2.1		 4wcxC-2o7rA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 7 PHE A 104
ILE A 103
GLY A  92
LEU A 222
 None
None
4PA  A 369 (-3.5A)
None
 0.70A 4zdzA-2o7rA:
undetectable		 4zdzA-2o7rA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 7 PHE A 104
ILE A 103
GLY A  92
LEU A 222
 None
None
4PA  A 369 (-3.5A)
None
 0.76A 4ze3A-2o7rA:
undetectable		 4ze3A-2o7rA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 6 GLU A 201
ASP A 295
ARG A 267
GLY A 196
 None
 0.84A 5cdnA-2o7rA:
undetectable
5cdnB-2o7rA:
3.4		 5cdnA-2o7rA:
21.30
5cdnB-2o7rA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 6 GLU A 201
ASP A 295
ARG A 267
GLY A 196
 None
 0.95A 5cdnC-2o7rA:
undetectable
5cdnD-2o7rA:
3.5		 5cdnC-2o7rA:
21.30
5cdnD-2o7rA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 8 SER A 169
ALA A 170
HIS A 306
LEU A 227
 4PA  A 369 (-1.8A)
4PA  A 369 (-3.2A)
4PA  A 369 (-4.8A)
None
 1.21A 5dzkd-2o7rA:
2.8
5dzkr-2o7rA:
undetectable		 5dzkd-2o7rA:
24.93
5dzkr-2o7rA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 6 PHE A  94
ALA A 135
HIS A  90
LEU A 126
 None
 1.29A 5dzkg-2o7rA:
3.0
5dzku-2o7rA:
undetectable		 5dzkg-2o7rA:
24.93
5dzku-2o7rA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 8 PHE A 104
ILE A 103
GLY A  92
LEU A 222
 None
None
4PA  A 369 (-3.5A)
None
 0.74A 5eseA-2o7rA:
undetectable		 5eseA-2o7rA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESF_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 8 PHE A 104
ILE A 103
GLY A  92
LEU A 222
 None
None
4PA  A 369 (-3.5A)
None
 0.73A 5esfA-2o7rA:
undetectable		 5esfA-2o7rA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 8 PHE A 104
ILE A 103
GLY A  92
LEU A 222
 None
None
4PA  A 369 (-3.5A)
None
 0.79A 5esjA-2o7rA:
undetectable		 5esjA-2o7rA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 7 PHE A 104
ILE A 103
GLY A  92
LEU A 222
 None
None
4PA  A 369 (-3.5A)
None
 0.69A 5esmA-2o7rA:
undetectable		 5esmA-2o7rA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS1_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 8 PHE A 104
ILE A 103
GLY A  92
LEU A 222
 None
None
4PA  A 369 (-3.5A)
None
 0.81A 5hs1A-2o7rA:
undetectable		 5hs1A-2o7rA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 12 PHE A 326
PHE A 319
GLY A 196
LEU A 199
MET A 269
 None
 1.15A 5v5zA-2o7rA:
undetectable		 5v5zA-2o7rA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 12 LEU A  96
GLY A  93
ILE A  38
GLY A  91
GLY A  92
 None
4PA  A 369 (-3.6A)
None
4PA  A 369 ( 3.8A)
4PA  A 369 (-3.5A)
 0.98A 5wyqB-2o7rA:
undetectable		 5wyqB-2o7rA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC607_0
(ALPHA-AMYLASE)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		4 / 6 GLY A 205
ASP A 228
GLY A 203
PRO A 202
 None
None
4PA  A 369 ( 3.7A)
None
 0.76A 6ag0C-2o7rA:
undetectable		 6ag0C-2o7rA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 2o7r CXE CARBOXYLESTERASE
(Actinidia
eriantha) 		5 / 8 GLY A 171
PHE A  89
VAL A 198
SER A 121
ALA A 120
 None
 1.37A 6hu9H-2o7rA:
undetectable
6hu9e-2o7rA:
undetectable		 6hu9H-2o7rA:
13.59
6hu9e-2o7rA:
15.63