SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o7t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2o7t TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		5 / 12 LEU A 130
LEU A 133
ALA A 134
VAL A  84
ILE A 150
 None
None
None
None
UNL  A 200 ( 4.3A)
 1.03A 1s9pC-2o7tA:
undetectable		 1s9pC-2o7tA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 2o7t TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		4 / 5 TYR A 149
TYR A 179
ILE A 156
GLY A 147
 None
None
None
UNL  A 200 ( 4.4A)
 1.35A 2du8J-2o7tA:
undetectable		 2du8J-2o7tA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2o7t TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		4 / 8 ASN A 126
THR A 129
LEU A 133
ALA A  73
 None
 0.78A 3kp6A-2o7tA:
undetectable		 3kp6A-2o7tA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2o7t TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		4 / 8 TYR A 149
TRP A  85
THR A  86
TYR A 179
 None
 1.35A 3wipC-2o7tA:
undetectable
3wipD-2o7tA:
undetectable		 3wipC-2o7tA:
22.58
3wipD-2o7tA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_D_ACHD301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2o7t TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		4 / 8 TYR A 149
TRP A  85
THR A  86
TYR A 179
 None
 1.38A 3wipD-2o7tA:
undetectable
3wipE-2o7tA:
undetectable		 3wipD-2o7tA:
22.58
3wipE-2o7tA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_F_ACHF301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2o7t TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		4 / 7 TYR A 149
TRP A  85
THR A  86
TYR A 179
 None
 1.37A 3wipF-2o7tA:
undetectable
3wipG-2o7tA:
undetectable		 3wipF-2o7tA:
22.58
3wipG-2o7tA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 2o7t TRANSCRIPTIONAL
REGULATOR
(Corynebacterium
glutamicum) 		3 / 3 THR A  16
ASN A  64
PHE A  63
 None
None
UNL  A 199 ( 3.7A)
 0.80A 4pd9A-2o7tA:
undetectable		 4pd9A-2o7tA:
19.48