SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o8i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 2o8i HYPOTHETICAL PROTEIN
ATU2327
(Agrobacterium
fabrum) 		4 / 5 ILE A 153
PHE A  48
PRO A  64
PHE A 113
 None
 1.27A 2ygnA-2o8iA:
undetectable		 2ygnA-2o8iA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 2o8i HYPOTHETICAL PROTEIN
ATU2327
(Agrobacterium
fabrum) 		4 / 6 ASP A 126
LEU A 128
LEU A  70
HIS A  97
 None
 1.03A 3bj8C-2o8iA:
undetectable
3bj8D-2o8iA:
undetectable		 3bj8C-2o8iA:
20.43
3bj8D-2o8iA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 2o8i HYPOTHETICAL PROTEIN
ATU2327
(Agrobacterium
fabrum) 		4 / 6 TYR A 107
PHE A 113
PRO A 114
LEU A  60
 None
 1.44A 3tgvB-2o8iA:
undetectable		 3tgvB-2o8iA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 2o8i HYPOTHETICAL PROTEIN
ATU2327
(Agrobacterium
fabrum) 		4 / 7 LEU A 158
ALA A  22
LEU A  33
ILE A  21
 None
 0.86A 4ubsA-2o8iA:
undetectable		 4ubsA-2o8iA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 2o8i HYPOTHETICAL PROTEIN
ATU2327
(Agrobacterium
fabrum) 		3 / 3 ARG A  10
LYS A   1
TYR A  26
 None
 1.38A 6gnaA-2o8iA:
undetectable		 6gnaA-2o8iA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 2o8i HYPOTHETICAL PROTEIN
ATU2327
(Agrobacterium
fabrum) 		3 / 3 ARG A  10
LYS A   1
TYR A  26
 None
 1.38A 6gnbA-2o8iA:
undetectable		 6gnbA-2o8iA:
22.07