SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o8p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 2o8p 14-3-3 DOMAIN
CONTAINING PROTEIN
(Cryptosporidium
parvum) 		3 / 3 ALA A  18
VAL A  20
TRP A  23
 None
 0.83A 1av2C-2o8pA:
undetectable
1av2D-2o8pA:
undetectable		 1av2C-2o8pA:
5.81
1av2D-2o8pA:
5.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 2o8p 14-3-3 DOMAIN
CONTAINING PROTEIN
(Cryptosporidium
parvum) 		3 / 3 ASP A 114
PHE A 109
VAL A 130
 None
 0.77A 1kijB-2o8pA:
undetectable		 1kijB-2o8pA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 2o8p 14-3-3 DOMAIN
CONTAINING PROTEIN
(Cryptosporidium
parvum) 		3 / 3 ALA A  18
VAL A  20
TRP A  23
 None
 0.85A 1nt5A-2o8pA:
undetectable		 1nt5A-2o8pA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 2o8p 14-3-3 DOMAIN
CONTAINING PROTEIN
(Cryptosporidium
parvum) 		3 / 3 ALA A  18
VAL A  20
TRP A  23
 None
 0.85A 1nt5B-2o8pA:
undetectable		 1nt5B-2o8pA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 2o8p 14-3-3 DOMAIN
CONTAINING PROTEIN
(Cryptosporidium
parvum) 		3 / 3 ALA A  18
VAL A  20
TRP A  23
 None
 0.87A 1nt6A-2o8pA:
undetectable		 1nt6A-2o8pA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 2o8p 14-3-3 DOMAIN
CONTAINING PROTEIN
(Cryptosporidium
parvum) 		3 / 3 ALA A  18
VAL A  20
TRP A  23
 None
 0.87A 1nt6B-2o8pA:
undetectable		 1nt6B-2o8pA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 2o8p 14-3-3 DOMAIN
CONTAINING PROTEIN
(Cryptosporidium
parvum) 		3 / 3 ALA A  18
VAL A  20
TRP A  23
 None
 0.82A 1w5uC-2o8pA:
undetectable
1w5uD-2o8pA:
undetectable		 1w5uC-2o8pA:
5.81
1w5uD-2o8pA:
5.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2o8p 14-3-3 DOMAIN
CONTAINING PROTEIN
(Cryptosporidium
parvum) 		4 / 5 ARG A  68
MET A  70
THR A  71
LEU A  98
 None
 1.35A 2eimJ-2o8pA:
undetectable		 2eimJ-2o8pA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2o8p 14-3-3 DOMAIN
CONTAINING PROTEIN
(Cryptosporidium
parvum) 		4 / 5 ARG A  68
MET A  70
THR A  71
LEU A  98
 None
 1.38A 2eimW-2o8pA:
undetectable		 2eimW-2o8pA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 2o8p 14-3-3 DOMAIN
CONTAINING PROTEIN
(Cryptosporidium
parvum) 		3 / 3 TRP A  23
ALA A  18
VAL A  20
 None
 0.81A 2izqA-2o8pA:
undetectable
2izqB-2o8pA:
undetectable		 2izqA-2o8pA:
5.81
2izqB-2o8pA:
5.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 2o8p 14-3-3 DOMAIN
CONTAINING PROTEIN
(Cryptosporidium
parvum) 		4 / 8 TYR A  39
GLU A  10
PHE A  48
SER A  46
 None
 1.07A 3jz0B-2o8pA:
4.4		 3jz0B-2o8pA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 2o8p 14-3-3 DOMAIN
CONTAINING PROTEIN
(Cryptosporidium
parvum) 		3 / 3 ALA A  18
VAL A  20
TRP A  23
 None
 0.81A 3l8lA-2o8pA:
undetectable
3l8lB-2o8pA:
undetectable		 3l8lA-2o8pA:
5.81
3l8lB-2o8pA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 2o8p 14-3-3 DOMAIN
CONTAINING PROTEIN
(Cryptosporidium
parvum) 		3 / 3 ALA A  18
VAL A  20
TRP A  23
 None
 0.82A 3l8lC-2o8pA:
undetectable
3l8lD-2o8pA:
undetectable		 3l8lC-2o8pA:
5.81
3l8lD-2o8pA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 2o8p 14-3-3 DOMAIN
CONTAINING PROTEIN
(Cryptosporidium
parvum) 		4 / 6 GLU A  52
LEU A  37
GLN A  14
LEU A  12
 None
 1.10A 5yvnA-2o8pA:
2.7		 5yvnA-2o8pA:
21.76