SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2o96'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 2o96 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 7
(Homo
sapiens) 		3 / 3 GLU A 156
ALA A 137
SER A 160
 None
 0.57A 1errB-2o96A:
undetectable		 1errB-2o96A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 2o96 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 7
(Homo
sapiens) 		4 / 5 LEU A  48
LEU A  40
MET A 112
THR A 135
 None
 1.40A 2oaxD-2o96A:
undetectable		 2oaxD-2o96A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2o96 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 7
(Homo
sapiens) 		4 / 7 THR A 159
GLU A 161
VAL A  10
VAL A  47
 None
 0.56A 3em0B-2o96A:
undetectable		 3em0B-2o96A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 2o96 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 7
(Homo
sapiens) 		5 / 9 GLY A  37
VAL A  19
SER A  18
VAL A  15
LEU A  14
 None
 1.04A 4qd3A-2o96A:
undetectable		 4qd3A-2o96A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 2o96 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 7
(Homo
sapiens) 		5 / 12 ILE A 108
ALA A 107
GLY A  98
GLY A  37
VAL A  36
 None
 0.97A 5i73A-2o96A:
undetectable		 5i73A-2o96A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2o96 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 7
(Homo
sapiens) 		5 / 12 ASP A  65
ASP A 105
GLY A  98
HIS A  96
PHE A  58
 None
 1.49A 6aphA-2o96A:
undetectable		 6aphA-2o96A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_1
(-)		 2o96 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 7
(Homo
sapiens) 		5 / 12 ASP A  65
ASP A 105
GLY A  98
HIS A  96
PHE A  58
 None
 1.48A 6f3mA-2o96A:
undetectable		 6f3mA-2o96A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_1
(-)		 2o96 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 7
(Homo
sapiens) 		5 / 12 ASP A  65
ASP A 105
GLY A  98
HIS A  96
PHE A  58
 None
 1.46A 6f3mB-2o96A:
undetectable		 6f3mB-2o96A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_1
(-)		 2o96 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 7
(Homo
sapiens) 		5 / 12 ASP A  65
ASP A 105
GLY A  98
HIS A  96
PHE A  58
 None
 1.48A 6f3mC-2o96A:
undetectable		 6f3mC-2o96A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_1
(-)		 2o96 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 7
(Homo
sapiens) 		5 / 12 ASP A  65
ASP A 105
GLY A  98
HIS A  96
PHE A  58
 None
 1.47A 6f3mD-2o96A:
undetectable		 6f3mD-2o96A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_1
(-)		 2o96 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 7
(Homo
sapiens) 		5 / 12 ASP A  65
ASP A 105
GLY A  98
HIS A  96
PHE A  58
 None
 1.49A 6f3nA-2o96A:
undetectable		 6f3nA-2o96A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_1
(-)		 2o96 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 7
(Homo
sapiens) 		5 / 12 ASP A  65
ASP A 105
GLY A  98
HIS A  96
PHE A  58
 None
 1.49A 6f3nB-2o96A:
undetectable		 6f3nB-2o96A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_1
(-)		 2o96 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 7
(Homo
sapiens) 		5 / 12 ASP A  65
ASP A 105
GLY A  98
HIS A  96
PHE A  58
 None
 1.49A 6f3nC-2o96A:
undetectable		 6f3nC-2o96A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_1
(-)		 2o96 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 7
(Homo
sapiens) 		5 / 12 ASP A  65
ASP A 105
GLY A  98
HIS A  96
PHE A  58
 None
 1.49A 6f3nD-2o96A:
undetectable		 6f3nD-2o96A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 2o96 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 7
(Homo
sapiens) 		5 / 12 GLY A  27
THR A  97
GLY A  98
ASP A 125
GLN A  32
 None
 1.16A 6gngA-2o96A:
undetectable		 6gngA-2o96A:
15.55