SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oaa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 6 HIS A 225
ALA A 212
GLY A 220
TYR A 213
 None
 1.11A 1l5qA-2oaaA:
undetectable		 1l5qA-2oaaA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 6 HIS A 225
ALA A 212
GLY A 220
TYR A 213
 None
 1.11A 1l5qB-2oaaA:
undetectable		 1l5qB-2oaaA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 6 HIS A 225
ALA A 212
GLY A 220
TYR A 213
 None
 1.10A 1l7xA-2oaaA:
undetectable		 1l7xA-2oaaA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 6 HIS A 225
ALA A 212
GLY A 220
TYR A 213
 None
 1.10A 1l7xB-2oaaA:
undetectable		 1l7xB-2oaaA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 7 LEU A 156
GLN A 155
LEU A 190
PHE A 187
 None
 1.06A 1v55C-2oaaA:
undetectable
1v55J-2oaaA:
undetectable		 1v55C-2oaaA:
20.00
1v55J-2oaaA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 7 LEU A 156
GLN A 155
LEU A 190
PHE A 187
 None
 1.01A 2dysP-2oaaA:
undetectable
2dysW-2oaaA:
undetectable		 2dysP-2oaaA:
20.00
2dysW-2oaaA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 7 LEU A 156
GLN A 155
LEU A 190
PHE A 187
 None
 1.01A 2eijP-2oaaA:
undetectable
2eijW-2oaaA:
undetectable		 2eijP-2oaaA:
20.00
2eijW-2oaaA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 8 LEU A 156
GLN A 155
LEU A 190
PHE A 187
 None
 0.98A 2eilP-2oaaA:
undetectable
2eilW-2oaaA:
undetectable		 2eilP-2oaaA:
20.00
2eilW-2oaaA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 7 LEU A 156
GLN A 155
LEU A 190
PHE A 187
 None
 1.01A 2eimC-2oaaA:
undetectable
2eimJ-2oaaA:
undetectable		 2eimC-2oaaA:
20.00
2eimJ-2oaaA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 7 LEU A 156
GLN A 155
LEU A 190
PHE A 187
 None
 1.04A 2einC-2oaaA:
undetectable
2einJ-2oaaA:
undetectable		 2einC-2oaaA:
20.00
2einJ-2oaaA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 6 LEU A 156
GLN A 155
LEU A 190
PHE A 187
 None
 1.11A 2einP-2oaaA:
undetectable
2einW-2oaaA:
undetectable		 2einP-2oaaA:
20.00
2einW-2oaaA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 7 SER A 183
SER A 167
VAL A 165
LEU A 237
 None
 0.95A 2hdnE-2oaaA:
undetectable
2hdnF-2oaaA:
undetectable
2hdnH-2oaaA:
undetectable		 2hdnE-2oaaA:
11.00
2hdnF-2oaaA:
21.57
2hdnH-2oaaA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 7 SER A 167
VAL A 165
LEU A 237
SER A 183
 None
 0.89A 2hdnF-2oaaA:
undetectable
2hdnG-2oaaA:
undetectable
2hdnH-2oaaA:
undetectable		 2hdnF-2oaaA:
21.57
2hdnG-2oaaA:
11.00
2hdnH-2oaaA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 2oaa R.MVAI
(Kocuria
varians) 		5 / 12 GLY A  30
ARG A  25
PHE A  35
ASP A  37
THR A  58
 None
 1.13A 2vdvE-2oaaA:
undetectable		 2vdvE-2oaaA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 2oaa R.MVAI
(Kocuria
varians) 		5 / 11 GLY A  30
ARG A  25
PHE A  35
ASP A  37
THR A  58
 None
 1.13A 2vdvF-2oaaA:
undetectable		 2vdvF-2oaaA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 6 LEU A 156
GLN A 155
LEU A 190
PHE A 187
 None
 1.03A 2zxwP-2oaaA:
undetectable
2zxwW-2oaaA:
undetectable		 2zxwP-2oaaA:
20.00
2zxwW-2oaaA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 5 GLN A 155
PHE A 229
LEU A 190
PHE A 187
 None
 1.46A 3ablC-2oaaA:
undetectable
3ablJ-2oaaA:
undetectable		 3ablC-2oaaA:
20.00
3ablJ-2oaaA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 7 LEU A 156
GLN A 155
LEU A 190
PHE A 187
 None
 0.94A 3ag2P-2oaaA:
undetectable
3ag2W-2oaaA:
undetectable		 3ag2P-2oaaA:
20.00
3ag2W-2oaaA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 6 HIS A 225
ALA A 212
GLY A 220
TYR A 213
 None
 1.14A 3dd1A-2oaaA:
undetectable		 3dd1A-2oaaA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 6 HIS A 225
ALA A 212
GLY A 220
TYR A 213
 None
 1.10A 3dd1B-2oaaA:
undetectable		 3dd1B-2oaaA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 6 HIS A 225
ALA A 212
GLY A 220
TYR A 213
 None
 1.10A 3ddsA-2oaaA:
undetectable		 3ddsA-2oaaA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 6 HIS A 225
ALA A 212
GLY A 220
TYR A 213
 None
 1.11A 3ddsB-2oaaA:
undetectable		 3ddsB-2oaaA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 6 HIS A 225
ALA A 212
GLY A 220
TYR A 213
 None
 1.11A 3ddwA-2oaaA:
undetectable		 3ddwA-2oaaA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 6 HIS A 225
ALA A 212
GLY A 220
TYR A 213
 None
 1.11A 3ddwB-2oaaA:
undetectable		 3ddwB-2oaaA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 2oaa R.MVAI
(Kocuria
varians) 		3 / 3 SER A 111
PHE A 118
LYS A 108
 None
 0.97A 3u88A-2oaaA:
undetectable		 3u88A-2oaaA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2oaa R.MVAI
(Kocuria
varians) 		3 / 3 ASP A  37
ARG A  25
LYS A  33
 None
 1.13A 3wipG-2oaaA:
undetectable		 3wipG-2oaaA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 8 ASP A  37
THR A  34
TRP A  20
LEU A  39
 None
 1.11A 5b1bA-2oaaA:
undetectable
5b1bC-2oaaA:
undetectable
5b1bP-2oaaA:
undetectable		 5b1bA-2oaaA:
17.83
5b1bC-2oaaA:
20.00
5b1bP-2oaaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 2oaa R.MVAI
(Kocuria
varians) 		3 / 3 HIS A 100
HIS A 225
HIS A 223
 None
 0.93A 5oexA-2oaaA:
undetectable		 5oexA-2oaaA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 2oaa R.MVAI
(Kocuria
varians) 		3 / 3 PHE A  51
ASP A  53
LEU A  69
 None
 0.66A 5uhbC-2oaaA:
undetectable		 5uhbC-2oaaA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHC_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 2oaa R.MVAI
(Kocuria
varians) 		3 / 3 PHE A  51
ASP A  53
LEU A  69
 None
 0.69A 5uhcC-2oaaA:
undetectable		 5uhcC-2oaaA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 7 ASP A  37
THR A  34
TRP A  20
LEU A  39
 None
 1.04A 6nmfA-2oaaA:
undetectable
6nmfC-2oaaA:
undetectable
6nmfP-2oaaA:
undetectable		 6nmfA-2oaaA:
17.83
6nmfC-2oaaA:
20.00
6nmfP-2oaaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2oaa R.MVAI
(Kocuria
varians) 		4 / 6 GLN A 155
PHE A 229
LEU A 190
PHE A 187
 None
 1.33A 6nmpC-2oaaA:
undetectable
6nmpJ-2oaaA:
undetectable		 6nmpC-2oaaA:
20.00
6nmpJ-2oaaA:
13.96