SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oae'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 12 LEU A  67
LEU A  76
SER A  85
VAL A 105
LEU A 114
 None
 1.36A 1db1A-2oaeA:
undetectable		 1db1A-2oaeA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_2
(EXOGLUCANASE 1)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 5 HIS A 749
TRP A 628
ALA A 655
TRP A 630
 None
 1.44A 1dy4A-2oaeA:
undetectable		 1dy4A-2oaeA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 12 GLU A 605
GLY A 642
PHE A 696
LEU A 724
PHE A 648
 None
 0.97A 1nw3A-2oaeA:
undetectable		 1nw3A-2oaeA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 ASP A 375
THR A 399
GLU A 422
 None
 0.86A 1pj7A-2oaeA:
2.0		 1pj7A-2oaeA:
22.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 ARG A 182
VAL A 165
TRP A 166
 None
 1.21A 1qwcA-2oaeA:
1.1		 1qwcA-2oaeA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 ARG A 182
VAL A 165
TRP A 166
 None
 1.26A 1vagA-2oaeA:
1.8		 1vagA-2oaeA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 VAL A 657
VAL A 689
TRP A 660
 None
 0.96A 1w5uC-2oaeA:
undetectable
1w5uD-2oaeA:
undetectable		 1w5uC-2oaeA:
2.25
1w5uD-2oaeA:
2.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		11 / 12 ARG A 123
GLU A 203
GLU A 204
PHE A 355
TYR A 548
VAL A 657
TYR A 663
TYR A 667
ASN A 711
VAL A 712
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
AIL  A 901 (-3.7A)
SO4  A 801 (-4.3A)
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 0.37A 1x70A-2oaeA:
52.5		 1x70A-2oaeA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		6 / 12 GLU A 203
PHE A 355
TYR A 548
VAL A 657
TYR A 663
VAL A 712
 AIL  A 901 (-3.8A)
AIL  A 901 (-3.7A)
SO4  A 801 (-4.3A)
None
AIL  A 901 (-4.3A)
AIL  A 901 (-4.9A)
 1.36A 1x70A-2oaeA:
52.5		 1x70A-2oaeA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 ARG A 356
SER A 631
TYR A 632
 AIL  A 901 ( 4.7A)
AIL  A 901 ( 2.8A)
None
 0.76A 1x70A-2oaeA:
52.5		 1x70A-2oaeA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_B_715B801_1
(DIPEPTIDYL PEPTIDASE
IV)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		11 / 12 ARG A 123
GLU A 203
GLU A 204
ARG A 356
SER A 631
VAL A 657
TYR A 663
TYR A 667
ASN A 711
VAL A 712
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
AIL  A 901 ( 4.7A)
AIL  A 901 ( 2.8A)
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 0.38A 1x70B-2oaeA:
52.6		 1x70B-2oaeA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 PHE A 355
TYR A 548
TYR A 632
 AIL  A 901 (-3.7A)
SO4  A 801 (-4.3A)
None
 0.20A 1x70B-2oaeA:
52.6		 1x70B-2oaeA:
84.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 ARG A 182
VAL A 165
TRP A 166
 None
 1.20A 1zviA-2oaeA:
undetectable		 1zviA-2oaeA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 VAL A 689
TRP A 660
VAL A 657
 None
 0.96A 2izqA-2oaeA:
undetectable
2izqB-2oaeA:
undetectable		 2izqA-2oaeA:
2.25
2izqB-2oaeA:
2.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		11 / 12 GLU A 203
GLU A 204
PHE A 355
TRP A 630
SER A 631
TYR A 632
VAL A 657
TYR A 663
TYR A 667
VAL A 712
HIS A 741
 AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
AIL  A 901 (-3.7A)
None
AIL  A 901 ( 2.8A)
None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 0.34A 2rguA-2oaeA:
52.0		 2rguA-2oaeA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		10 / 12 GLU A 203
GLU A 204
PHE A 355
TYR A 548
TRP A 630
TYR A 632
VAL A 657
TYR A 663
TYR A 667
HIS A 741
 AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
AIL  A 901 (-3.7A)
SO4  A 801 (-4.3A)
None
None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
SO4  A 801 (-4.1A)
 0.62A 2rguA-2oaeA:
52.0		 2rguA-2oaeA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 12 GLU A 203
PHE A 355
SER A 631
VAL A 657
VAL A 712
 AIL  A 901 (-3.8A)
AIL  A 901 (-3.7A)
AIL  A 901 ( 2.8A)
None
AIL  A 901 (-4.9A)
 1.26A 2rguA-2oaeA:
52.0		 2rguA-2oaeA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 12 GLU A 204
SER A 631
VAL A 657
TYR A 663
VAL A 712
 AIL  A 901 (-2.9A)
AIL  A 901 ( 2.8A)
None
AIL  A 901 (-4.3A)
AIL  A 901 (-4.9A)
 1.24A 2rguA-2oaeA:
52.0		 2rguA-2oaeA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		10 / 11 GLU A 203
GLU A 204
TRP A 630
SER A 631
TYR A 632
VAL A 657
TYR A 663
TYR A 667
VAL A 712
HIS A 741
 AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
None
AIL  A 901 ( 2.8A)
None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 0.35A 2rguB-2oaeA:
52.0		 2rguB-2oaeA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		9 / 11 GLU A 203
GLU A 204
TYR A 548
TRP A 630
TYR A 632
VAL A 657
TYR A 663
TYR A 667
HIS A 741
 AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
SO4  A 801 (-4.3A)
None
None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
SO4  A 801 (-4.1A)
 0.62A 2rguB-2oaeA:
52.0		 2rguB-2oaeA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 11 TRP A 630
TYR A 635
TYR A 663
VAL A 712
HIS A 741
 None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 1.14A 2rguB-2oaeA:
52.0		 2rguB-2oaeA:
84.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9H_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 10 LEU A 298
ALA A 211
VAL A 301
ILE A 268
PHE A 266
 None
 1.10A 2w9hA-2oaeA:
undetectable		 2w9hA-2oaeA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1305_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 5 SER A 347
PRO A 357
GLY A 353
TRP A 351
 None
 1.27A 2y7kB-2oaeA:
undetectable		 2y7kB-2oaeA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 6 SER A 347
PRO A 357
GLY A 353
TRP A 351
 None
 1.21A 2y7pA-2oaeA:
undetectable		 2y7pA-2oaeA:
14.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		12 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 548
SER A 631
TYR A 632
VAL A 657
TYR A 663
TYR A 667
ASN A 711
VAL A 712
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
SO4  A 801 (-4.3A)
AIL  A 901 ( 2.8A)
None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 0.46A 3bjmA-2oaeA:
52.2		 3bjmA-2oaeA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		6 / 12 GLU A 204
TYR A 548
SER A 631
VAL A 657
TYR A 663
VAL A 712
 AIL  A 901 (-2.9A)
SO4  A 801 (-4.3A)
AIL  A 901 ( 2.8A)
None
AIL  A 901 (-4.3A)
AIL  A 901 (-4.9A)
 1.17A 3bjmA-2oaeA:
52.2		 3bjmA-2oaeA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 12 TYR A 635
TYR A 663
ASN A 711
VAL A 712
HIS A 741
 None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 1.05A 3bjmA-2oaeA:
52.2		 3bjmA-2oaeA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		12 / 12 ARG A 123
GLU A 203
GLU A 204
PHE A 355
TYR A 548
SER A 631
VAL A 657
TYR A 663
TYR A 667
ASN A 711
VAL A 712
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
AIL  A 901 (-3.7A)
SO4  A 801 (-4.3A)
AIL  A 901 ( 2.8A)
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 0.53A 3bjmB-2oaeA:
52.2		 3bjmB-2oaeA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		6 / 12 GLU A 203
PHE A 355
TYR A 548
SER A 631
VAL A 657
VAL A 712
 AIL  A 901 (-3.8A)
AIL  A 901 (-3.7A)
SO4  A 801 (-4.3A)
AIL  A 901 ( 2.8A)
None
AIL  A 901 (-4.9A)
 1.28A 3bjmB-2oaeA:
52.2		 3bjmB-2oaeA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 12 GLU A 204
TYR A 548
SER A 631
VAL A 657
TYR A 663
 AIL  A 901 (-2.9A)
SO4  A 801 (-4.3A)
AIL  A 901 ( 2.8A)
None
AIL  A 901 (-4.3A)
 1.18A 3bjmB-2oaeA:
52.2		 3bjmB-2oaeA:
84.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		11 / 12 ARG A 123
GLU A 203
GLU A 204
SER A 631
TYR A 632
VAL A 657
TYR A 663
TYR A 667
ASN A 711
VAL A 712
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
AIL  A 901 ( 2.8A)
None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 0.58A 3g0bA-2oaeA:
52.5		 3g0bA-2oaeA:
84.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		10 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 548
TYR A 632
VAL A 657
TYR A 663
TYR A 667
ASN A 711
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
SO4  A 801 (-4.3A)
None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-3.1A)
SO4  A 801 (-4.1A)
 0.63A 3g0bA-2oaeA:
52.5		 3g0bA-2oaeA:
84.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		6 / 12 SER A 631
TYR A 635
TYR A 663
ASN A 711
VAL A 712
HIS A 741
 AIL  A 901 ( 2.8A)
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 1.30A 3g0bA-2oaeA:
52.5		 3g0bA-2oaeA:
84.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		11 / 12 ARG A 123
GLU A 203
GLU A 204
SER A 631
TYR A 632
VAL A 657
TYR A 663
TYR A 667
ASN A 711
VAL A 712
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
AIL  A 901 ( 2.8A)
None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 0.59A 3g0bB-2oaeA:
52.1		 3g0bB-2oaeA:
84.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		10 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 548
TYR A 632
VAL A 657
TYR A 663
TYR A 667
ASN A 711
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
SO4  A 801 (-4.3A)
None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-3.1A)
SO4  A 801 (-4.1A)
 0.64A 3g0bB-2oaeA:
52.1		 3g0bB-2oaeA:
84.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		6 / 12 SER A 631
TYR A 635
TYR A 663
ASN A 711
VAL A 712
HIS A 741
 AIL  A 901 ( 2.8A)
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 1.32A 3g0bB-2oaeA:
52.1		 3g0bB-2oaeA:
84.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		11 / 12 ARG A 123
GLU A 203
GLU A 204
SER A 631
TYR A 632
VAL A 657
TYR A 663
TYR A 667
ASN A 711
VAL A 712
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
AIL  A 901 ( 2.8A)
None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 0.59A 3g0bC-2oaeA:
52.1		 3g0bC-2oaeA:
84.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		10 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 548
TYR A 632
VAL A 657
TYR A 663
TYR A 667
ASN A 711
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
SO4  A 801 (-4.3A)
None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-3.1A)
SO4  A 801 (-4.1A)
 0.64A 3g0bC-2oaeA:
52.1		 3g0bC-2oaeA:
84.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 12 SER A 631
TYR A 635
ASN A 711
VAL A 712
HIS A 741
 AIL  A 901 ( 2.8A)
None
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 1.19A 3g0bC-2oaeA:
52.1		 3g0bC-2oaeA:
84.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		11 / 12 ARG A 123
GLU A 203
GLU A 204
SER A 631
TYR A 632
VAL A 657
TYR A 663
TYR A 667
ASN A 711
VAL A 712
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
AIL  A 901 ( 2.8A)
None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 0.59A 3g0bD-2oaeA:
52.5		 3g0bD-2oaeA:
84.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		10 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 548
TYR A 632
VAL A 657
TYR A 663
TYR A 667
ASN A 711
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
SO4  A 801 (-4.3A)
None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-3.1A)
SO4  A 801 (-4.1A)
 0.63A 3g0bD-2oaeA:
52.5		 3g0bD-2oaeA:
84.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		6 / 12 SER A 631
TYR A 635
TYR A 663
ASN A 711
VAL A 712
HIS A 741
 AIL  A 901 ( 2.8A)
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 1.32A 3g0bD-2oaeA:
52.5		 3g0bD-2oaeA:
84.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 4 GLY A 475
TYR A 457
GLY A 429
ASP A 557
 None
 1.17A 3kl3A-2oaeA:
undetectable		 3kl3A-2oaeA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 6 LEU A 760
SER A 757
PHE A 759
ILE A 652
 None
 1.00A 3ko0B-2oaeA:
undetectable		 3ko0B-2oaeA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 VAL A 657
VAL A 689
TRP A 660
 None
 0.92A 3l8lC-2oaeA:
undetectable
3l8lD-2oaeA:
undetectable		 3l8lC-2oaeA:
2.25
3l8lD-2oaeA:
2.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_C_URFC521_1
(RNA DEPENDENT RNA
POLYMERASE)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 5 ASP A 740
ASP A 709
ASP A 710
ARG A 123
 None
None
None
SO4  A 801 ( 3.1A)
 1.27A 3naiC-2oaeA:
undetectable		 3naiC-2oaeA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 8 TRP A 313
VAL A 301
TRP A 213
PHE A 206
 None
 1.33A 3v35A-2oaeA:
undetectable		 3v35A-2oaeA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 6 ASP A 228
GLY A 230
VAL A 231
THR A 263
 None
 1.12A 3vqrA-2oaeA:
undetectable		 3vqrA-2oaeA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 5 ASP A 228
GLY A 230
VAL A 231
THR A 263
 None
 1.11A 3vqrB-2oaeA:
undetectable		 3vqrB-2oaeA:
20.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		12 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 548
SER A 631
TYR A 632
VAL A 657
TYR A 663
TYR A 667
ASN A 711
VAL A 712
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
SO4  A 801 (-4.3A)
AIL  A 901 ( 2.8A)
None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 0.44A 3w2tA-2oaeA:
52.3		 3w2tA-2oaeA:
84.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 12 GLU A 203
TYR A 548
SER A 631
TYR A 663
VAL A 712
 AIL  A 901 (-3.8A)
SO4  A 801 (-4.3A)
AIL  A 901 ( 2.8A)
AIL  A 901 (-4.3A)
AIL  A 901 (-4.9A)
 1.13A 3w2tA-2oaeA:
52.3		 3w2tA-2oaeA:
84.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		12 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 548
SER A 631
TYR A 632
VAL A 657
TYR A 663
TYR A 667
ASN A 711
VAL A 712
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
SO4  A 801 (-4.3A)
AIL  A 901 ( 2.8A)
None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 0.42A 3w2tB-2oaeA:
52.2		 3w2tB-2oaeA:
84.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		6 / 12 GLU A 204
TYR A 548
SER A 631
VAL A 657
TYR A 663
VAL A 712
 AIL  A 901 (-2.9A)
SO4  A 801 (-4.3A)
AIL  A 901 ( 2.8A)
None
AIL  A 901 (-4.3A)
AIL  A 901 (-4.9A)
 1.17A 3w2tB-2oaeA:
52.2		 3w2tB-2oaeA:
84.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1224_0
(THAUMATIN-LIKE
PROTEIN)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 5 SER A 413
GLU A 465
THR A 412
ASP A  63
 None
 1.42A 3zs3A-2oaeA:
0.0		 3zs3A-2oaeA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 GLU A 345
GLY A 353
SER A 321
 None
 0.67A 4b53B-2oaeA:
undetectable		 4b53B-2oaeA:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFU_A_KANA401_1
(APH(2')-ID)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 12 ASP A 740
GLU A 203
GLU A 202
GLU A 204
TYR A 236
 None
AIL  A 901 (-3.8A)
None
AIL  A 901 (-2.9A)
None
 1.50A 4dfuA-2oaeA:
2.3		 4dfuA-2oaeA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFU_B_KANB402_1
(APH(2')-ID)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 12 ASP A 740
GLU A 203
GLU A 202
GLU A 204
TYR A 236
 None
AIL  A 901 (-3.8A)
None
AIL  A 901 (-2.9A)
None
 1.50A 4dfuB-2oaeA:
2.3		 4dfuB-2oaeA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 11 SER A 645
GLY A 644
ILE A 608
ILE A 545
ILE A 627
 None
 1.06A 4dt8A-2oaeA:
undetectable		 4dt8A-2oaeA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 8 ASN A 711
ASP A 709
VAL A 657
HIS A 705
 AIL  A 901 (-3.1A)
None
None
None
 1.22A 4f5zA-2oaeA:
13.4		 4f5zA-2oaeA:
17.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		12 / 12 ARG A 123
GLU A 203
GLU A 204
GLY A 207
ARG A 356
TYR A 548
SER A 631
VAL A 657
TYR A 663
ASN A 711
VAL A 712
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
AIL  A 901 ( 4.1A)
AIL  A 901 ( 4.7A)
SO4  A 801 (-4.3A)
AIL  A 901 ( 2.8A)
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 0.44A 4ffwA-2oaeA:
52.2		 4ffwA-2oaeA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 PHE A 355
TYR A 632
TYR A 667
 AIL  A 901 (-3.7A)
None
AIL  A 901 (-3.8A)
 0.31A 4ffwA-2oaeA:
52.2		 4ffwA-2oaeA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		12 / 12 ARG A 123
GLU A 203
GLU A 204
GLY A 207
PHE A 355
TYR A 548
SER A 631
VAL A 657
TYR A 663
TYR A 667
VAL A 712
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
AIL  A 901 ( 4.1A)
AIL  A 901 (-3.7A)
SO4  A 801 (-4.3A)
AIL  A 901 ( 2.8A)
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 0.48A 4ffwB-2oaeA:
52.2		 4ffwB-2oaeA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		7 / 12 GLU A 203
GLY A 207
PHE A 355
TYR A 548
SER A 631
VAL A 657
VAL A 712
 AIL  A 901 (-3.8A)
AIL  A 901 ( 4.1A)
AIL  A 901 (-3.7A)
SO4  A 801 (-4.3A)
AIL  A 901 ( 2.8A)
None
AIL  A 901 (-4.9A)
 1.46A 4ffwB-2oaeA:
52.2		 4ffwB-2oaeA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 ARG A 356
TYR A 632
ASN A 711
 AIL  A 901 ( 4.7A)
None
AIL  A 901 (-3.1A)
 0.53A 4ffwB-2oaeA:
52.2		 4ffwB-2oaeA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 5 TYR A 133
ILE A 132
ASN A 136
ILE A 141
 None
 0.90A 4jtpA-2oaeA:
undetectable		 4jtpA-2oaeA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 5 TYR A 297
ARG A 316
GLU A 204
VAL A 712
 None
None
AIL  A 901 (-2.9A)
AIL  A 901 (-4.9A)
 1.43A 4nkvB-2oaeA:
undetectable		 4nkvB-2oaeA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 12 ILE A 325
ASP A 327
TRP A 335
THR A 219
ALA A 222
 None
 1.41A 4u14A-2oaeA:
undetectable		 4u14A-2oaeA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 MET A 323
GLN A 318
TYR A 297
 None
 0.69A 4udcA-2oaeA:
undetectable		 4udcA-2oaeA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 8 ASP A 710
ASP A 740
ASP A 709
ILE A 752
 None
 1.01A 4xjeA-2oaeA:
undetectable		 4xjeA-2oaeA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 7 ASN A 190
PRO A 253
TRP A 122
TYR A 209
 None
 1.49A 5amjB-2oaeA:
0.0		 5amjB-2oaeA:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 12 LEU A 471
GLY A 472
ARG A 474
TYR A 457
LEU A 450
 None
 1.26A 5czyA-2oaeA:
undetectable		 5czyA-2oaeA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 ARG A 182
VAL A 165
TRP A 166
 None
 1.11A 5fvoA-2oaeA:
1.6		 5fvoA-2oaeA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 ARG A 493
ASN A  78
ASP A  63
 None
 0.92A 5gwxA-2oaeA:
undetectable		 5gwxA-2oaeA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 SER A  55
TYR A  56
TYR A 481
 None
 0.82A 5lakA-2oaeA:
0.8
5lakI-2oaeA:
undetectable		 5lakA-2oaeA:
18.91
5lakI-2oaeA:
4.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		3 / 3 SER A  55
TYR A  56
TYR A 481
 None
 0.79A 5lakC-2oaeA:
undetectable
5lakJ-2oaeA:
undetectable		 5lakC-2oaeA:
18.91
5lakJ-2oaeA:
4.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 8 ILE A 372
VAL A 405
THR A 399
ILE A 398
 None
 0.85A 5mzrE-2oaeA:
undetectable		 5mzrE-2oaeA:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 7 ASN A 190
PRO A 253
TRP A 122
TYR A 209
 None
 1.48A 5oh1B-2oaeA:
undetectable		 5oh1B-2oaeA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 7 ASN A 190
PRO A 253
TRP A 122
TYR A 209
 None
 1.46A 5oh3B-2oaeA:
0.0		 5oh3B-2oaeA:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 12 ILE A 704
ALA A 653
THR A 637
ILE A 627
ALA A 626
 None
 0.90A 5vceA-2oaeA:
undetectable		 5vceA-2oaeA:
19.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		12 / 12 ARG A 123
GLU A 203
GLU A 204
TYR A 548
SER A 631
TYR A 632
VAL A 657
TYR A 663
TYR A 667
ASN A 711
VAL A 712
HIS A 741
 SO4  A 801 ( 3.1A)
AIL  A 901 (-3.8A)
AIL  A 901 (-2.9A)
SO4  A 801 (-4.3A)
AIL  A 901 ( 2.8A)
None
None
AIL  A 901 (-4.3A)
AIL  A 901 (-3.8A)
AIL  A 901 (-3.1A)
AIL  A 901 (-4.9A)
SO4  A 801 (-4.1A)
 0.44A 6b1eB-2oaeA:
44.5		 6b1eB-2oaeA:
84.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		5 / 6 ALA A 163
SER A 156
GLY A 218
ILE A 268
PHE A 266
 None
 1.47A 6f8cA-2oaeA:
undetectable		 6f8cA-2oaeA:
7.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 2oae DIPEPTIDYL PEPTIDASE
4
(Rattus
norvegicus) 		4 / 6 ILE A 595
GLY A 550
TYR A 671
GLU A 603
 None
 1.06A 6gqiA-2oaeA:
undetectable		 6gqiA-2oaeA:
20.33