SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oaj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 6 GLY A 507
ALA A 558
TYR A 506
GLU A 559
None
0.83A 1dmaB-2oajA:
undetectable
1dmaB-2oajA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_2
(HMG-COA REDUCTASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
5 / 11 HIS A 632
ASN A 634
SER A 602
LEU A 603
LEU A 543
None
1.32A 1hwkD-2oajA:
undetectable
1hwkD-2oajA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_1
(HMG-COA REDUCTASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
5 / 11 HIS A 632
ASN A 634
SER A 602
LEU A 603
LEU A 543
None
1.32A 1hwkC-2oajA:
undetectable
1hwkC-2oajA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 6 HIS A 102
LEU A 460
LEU A 457
PRO A 454
None
1.28A 1hz4A-2oajA:
undetectable
1hz4A-2oajA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
5 / 12 ILE A 529
GLY A 507
ALA A 524
PRO A 503
ALA A 504
None
1.07A 1sg9C-2oajA:
undetectable
1sg9C-2oajA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 8 THR A 153
LEU A 192
VAL A 133
VAL A 143
None
0.88A 1t86A-2oajA:
undetectable
1t86A-2oajA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
3 / 3 LEU A 426
LEU A 440
SER A 443
None
0.66A 1tlmA-2oajA:
undetectable
1tlmA-2oajA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
5 / 12 LEU A 790
LEU A 787
LEU A 809
MET A 693
THR A 716
None
1.38A 1ya3A-2oajA:
undetectable
1ya3A-2oajA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 5 ILE A 688
ILE A 703
MET A 764
LEU A 574
None
0.74A 1zgyA-2oajA:
undetectable
1zgyA-2oajA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
5 / 12 LEU A 790
LEU A 787
LEU A 809
MET A 693
THR A 716
None
1.41A 2aa5B-2oajA:
undetectable
2aa5B-2oajA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 5 LEU A 543
PHE A 575
VAL A 613
ALA A 630
None
1.19A 2cizA-2oajA:
undetectable
2cizA-2oajA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
5 / 12 GLY A 507
ALA A 470
ALA A 873
ALA A 524
PHE A 510
None
1.03A 2gluB-2oajA:
undetectable
2gluB-2oajA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 8 VAL A 227
ASN A 220
PHE A 249
ALA A 300
None
1.18A 2ij7C-2oajA:
undetectable
2ij7C-2oajA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
3 / 3 SER A 682
GLY A 712
GLY A 708
None
0.53A 3bogA-2oajA:
undetectable
3bogC-2oajA:
undetectable
3bogA-2oajA:
undetectable
3bogC-2oajA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_A_SAMA501_0
(SPERMIDINE SYNTHASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
5 / 12 ILE A 214
GLY A 176
VAL A 157
GLY A 180
THR A 162
None
1.00A 3bwcA-2oajA:
2.1
3bwcA-2oajA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 6 VAL A 134
LEU A 174
MET A 173
ILE A 103
None
0.96A 3gcsA-2oajA:
undetectable
3gcsA-2oajA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
5 / 12 ILE A 812
PHE A  66
SER A 810
ILE A 828
LEU A 836
None
0.90A 3k2hB-2oajA:
undetectable
3k2hB-2oajA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
5 / 10 ILE A 357
ALA A 332
ILE A 408
ILE A 368
ILE A 287
None
1.25A 3prsA-2oajA:
undetectable
3prsA-2oajA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 7 LEU A 830
LEU A 836
PRO A 853
ILE A 852
None
0.94A 3s56B-2oajA:
undetectable
3s56B-2oajA:
7.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_2
(HIV-1 PROTEASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
5 / 12 LEU A 610
VAL A 572
ILE A 641
THR A 629
VAL A 631
None
0.96A 3so9B-2oajA:
undetectable
3so9B-2oajA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 7 LEU A 790
GLY A 712
ILE A 743
THR A 716
None
0.79A 3spkB-2oajA:
undetectable
3spkB-2oajA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 6 SER A 739
HIS A 744
THR A 738
ARG A 786
None
1.41A 3thrB-2oajA:
2.1
3thrB-2oajA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
3 / 3 PHE A 418
CYH A 341
HIS A 422
None
0.96A 3u9fF-2oajA:
undetectable
3u9fF-2oajA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
3 / 3 PHE A 418
CYH A 341
HIS A 422
None
0.94A 3u9fG-2oajA:
undetectable
3u9fG-2oajA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
3 / 3 PHE A 418
CYH A 341
HIS A 422
None
0.95A 3u9fL-2oajA:
undetectable
3u9fL-2oajA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
3 / 3 PHE A 418
CYH A 341
HIS A 422
None
0.95A 3u9fS-2oajA:
undetectable
3u9fS-2oajA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 8 GLY A 507
ALA A 558
TYR A 506
GLU A 559
None
0.84A 3u9hA-2oajA:
undetectable
3u9hA-2oajA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 8 GLY A 507
ALA A 558
TYR A 506
GLU A 559
None
0.81A 3u9hB-2oajA:
undetectable
3u9hB-2oajA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 8 ILE A 352
ILE A 368
GLU A 313
THR A 314
None
0.88A 3ua5A-2oajA:
undetectable
3ua5A-2oajA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 5 PHE A 844
LEU A 804
GLY A 781
THR A 738
None
0.95A 3wrkD-2oajA:
undetectable
3wrkD-2oajA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
3 / 3 TYR A 131
ASP A 171
ASP A 167
None
0.88A 4a6eA-2oajA:
undetectable
4a6eA-2oajA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 6 SER A 294
THR A 314
ILE A 316
THR A 288
None
1.03A 4acbC-2oajA:
undetectable
4acbC-2oajA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 8 GLY A 507
ALA A 558
TYR A 506
GLU A 559
None
0.81A 4bjcA-2oajA:
undetectable
4bjcA-2oajA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CD2_A_FOLA207_0
(DIHYDROFOLATE
REDUCTASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
5 / 12 ALA A 557
ILE A 646
PHE A 690
PHE A 727
LEU A 660
None
1.20A 4cd2A-2oajA:
undetectable
4cd2A-2oajA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 8 ILE A 405
LEU A 399
ILE A 352
GLY A 444
None
0.85A 4hb6A-2oajA:
undetectable
4hb6A-2oajA:
6.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 8 ILE A 408
LEU A 351
ILE A 411
GLY A 444
None
0.89A 4hb6A-2oajA:
undetectable
4hb6A-2oajA:
6.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 8 ILE A 405
LEU A 399
ILE A 352
GLY A 444
None
0.83A 4hb8A-2oajA:
undetectable
4hb8A-2oajA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 6 TYR A 717
GLU A 713
THR A 709
LEU A 731
None
1.47A 4qzuC-2oajA:
undetectable
4qzuC-2oajA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
3 / 3 ALA A  93
TYR A 104
PRO A  80
None
0.72A 4zdyA-2oajA:
undetectable
4zdyA-2oajA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
5 / 10 ALA A  93
ILE A 103
GLY A 129
PHE A 126
SER A 145
None
1.02A 5i6xA-2oajA:
undetectable
5i6xA-2oajA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 6 ILE A 164
GLY A 180
ASN A 179
ILE A 217
None
0.95A 5j4nB-2oajA:
undetectable
5j4nB-2oajA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
3 / 3 VAL A 649
ARG A 616
PRO A 627
None
0.83A 5koxA-2oajA:
undetectable
5koxA-2oajA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 9 ILE A 250
PHE A 205
VAL A 274
THR A 288
None
1.04A 5lg3I-2oajA:
undetectable
5lg3I-2oajA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
5 / 9 ALA A 873
ILE A 872
ILE A 861
ALA A 806
LEU A 830
None
1.02A 5mvmA-2oajA:
undetectable
5mvmE-2oajA:
undetectable
5mvmA-2oajA:
6.88
5mvmE-2oajA:
6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
3 / 3 TRP A 298
MET A 307
ASN A 317
None
1.45A 5uc1A-2oajA:
undetectable
5uc1A-2oajA:
6.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
3 / 3 LYS A 754
LEU A 787
ASP A 843
None
0.76A 5zv2A-2oajA:
undetectable
5zv2A-2oajA:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)
2oaj PROTEIN SNI1
(Saccharomyces
cerevisiae)
4 / 7 ILE A 554
GLU A 536
HIS A 514
VAL A 551
None
1.02A 6j20A-2oajA:
undetectable
6j20A-2oajA:
19.49