SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ob5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 2ob5 HYPOTHETICAL PROTEIN
ATU2016
(Agrobacterium
fabrum) 		4 / 7 VAL A  44
LEU A  48
LEU A   9
ALA A  61
 None
 0.86A 1j8uA-2ob5A:
undetectable		 1j8uA-2ob5A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 2ob5 HYPOTHETICAL PROTEIN
ATU2016
(Agrobacterium
fabrum) 		4 / 7 VAL A  53
VAL A  13
LEU A  14
ALA A  61
 None
 0.89A 1pthA-2ob5A:
undetectable		 1pthA-2ob5A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 2ob5 HYPOTHETICAL PROTEIN
ATU2016
(Agrobacterium
fabrum) 		4 / 7 VAL A  53
VAL A  13
LEU A  14
ALA A  61
 None
 0.88A 1pthB-2ob5A:
undetectable		 1pthB-2ob5A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 2ob5 HYPOTHETICAL PROTEIN
ATU2016
(Agrobacterium
fabrum) 		6 / 12 ILE A 146
LEU A  63
ALA A  61
LEU A  17
LEU A  14
VAL A  13
 None
 1.27A 2yqzB-2ob5A:
undetectable		 2yqzB-2ob5A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 2ob5 HYPOTHETICAL PROTEIN
ATU2016
(Agrobacterium
fabrum) 		4 / 7 GLU A  94
ARG A 134
GLU A 132
SER A  54
 None
 1.16A 2zt7A-2ob5A:
undetectable		 2zt7A-2ob5A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 2ob5 HYPOTHETICAL PROTEIN
ATU2016
(Agrobacterium
fabrum) 		3 / 3 THR A  31
LYS A  -3
GLU A 132
 None
 0.90A 3ijdB-2ob5A:
undetectable		 3ijdB-2ob5A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2ob5 HYPOTHETICAL PROTEIN
ATU2016
(Agrobacterium
fabrum) 		4 / 6 GLU A  94
THR A 133
ALA A  56
ALA A  55
 None
 1.14A 3ns1C-2ob5A:
undetectable		 3ns1C-2ob5A:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 2ob5 HYPOTHETICAL PROTEIN
ATU2016
(Agrobacterium
fabrum) 		3 / 3 VAL A  38
TYR A 118
ALA A 121
 None
 0.52A 4ybnA-2ob5A:
undetectable		 4ybnA-2ob5A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		 2ob5 HYPOTHETICAL PROTEIN
ATU2016
(Agrobacterium
fabrum) 		5 / 10 ILE A 128
TYR A 125
THR A  43
THR A  42
ASP A  30
 None
 1.49A 6b5yC-2ob5A:
0.0
6b5yD-2ob5A:
0.0		 6b5yC-2ob5A:
16.67
6b5yD-2ob5A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		 2ob5 HYPOTHETICAL PROTEIN
ATU2016
(Agrobacterium
fabrum) 		5 / 9 ILE A 128
TYR A 125
THR A  43
THR A  42
ASP A  30
 None
 1.45A 6b68A-2ob5A:
undetectable
6b68B-2ob5A:
undetectable		 6b68A-2ob5A:
16.67
6b68B-2ob5A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		 2ob5 HYPOTHETICAL PROTEIN
ATU2016
(Agrobacterium
fabrum) 		5 / 9 ILE A 128
TYR A 125
THR A  43
THR A  42
ASP A  30
 None
 1.49A 6b69A-2ob5A:
undetectable
6b69B-2ob5A:
0.0		 6b69A-2ob5A:
16.67
6b69B-2ob5A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_C_9F2C302_1
(BETA-LACTAMASE)		 2ob5 HYPOTHETICAL PROTEIN
ATU2016
(Agrobacterium
fabrum) 		5 / 9 ILE A 128
TYR A 125
THR A  43
THR A  42
ASP A  30
 None
 1.45A 6b69C-2ob5A:
undetectable
6b69D-2ob5A:
undetectable		 6b69C-2ob5A:
16.67
6b69D-2ob5A:
16.67