SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2obe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 12 TYR A 681
TYR A 687
TYR A 897
LEU A 633
LEU A 694
 MPD  A1704 ( 4.7A)
None
None
None
None
 1.41A 1fmlA-2obeA:
undetectable		 1fmlA-2obeA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 7 PHE A 655
PHE A 855
ALA A 654
PHE A 903
 None
None
None
MPD  A1706 ( 4.2A)
 1.19A 1fxvA-2obeA:
undetectable
1fxvB-2obeA:
undetectable		 1fxvA-2obeA:
12.45
1fxvB-2obeA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_0
(N,N-DIMETHYLGLYCINE
OXIDASE)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 12 TYR A 561
GLY A 331
ASN A 337
LEU A 554
PHE A 100
 None
 1.19A 1pj7A-2obeA:
undetectable		 1pj7A-2obeA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 7 PHE A 692
ASN A 695
SER A 659
ARG A 852
 None
 1.30A 1rqpB-2obeA:
undetectable		 1rqpB-2obeA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE507_0
(NAD-DEPENDENT
DEACETYLASE 2)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 7 LEU A 353
ASN A 313
ILE A 315
ASP A 312
 None
 0.97A 1yc2E-2obeA:
undetectable		 1yc2E-2obeA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 8 ARG A 656
SER A 861
LEU A 353
LEU A 627
 MPD  A1706 (-3.6A)
None
None
None
 0.97A 2bfpA-2obeA:
undetectable		 2bfpA-2obeA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 8 ARG A 656
SER A 861
LEU A 353
LEU A 627
 MPD  A1706 (-3.6A)
None
None
None
 1.00A 2bfpB-2obeA:
undetectable		 2bfpB-2obeA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 8 ARG A 656
SER A 861
LEU A 353
LEU A 627
 MPD  A1706 (-3.6A)
None
None
None
 0.96A 2bfpC-2obeA:
undetectable		 2bfpC-2obeA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 8 ARG A 656
SER A 861
LEU A 353
LEU A 627
 MPD  A1706 (-3.6A)
None
None
None
 0.98A 2bfpD-2obeA:
undetectable		 2bfpD-2obeA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 8 LEU A 573
SER A 587
LEU A 106
ASP A 107
 None
 1.06A 2j2pA-2obeA:
undetectable
2j2pB-2obeA:
undetectable		 2j2pA-2obeA:
13.27
2j2pB-2obeA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 6 ASP A 730
ARG A 727
ASP A 744
THR A 719
 2HP  A1610 (-3.8A)
None
None
None
 1.17A 2j2pE-2obeA:
undetectable
2j2pF-2obeA:
undetectable		 2j2pE-2obeA:
13.27
2j2pF-2obeA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 7 TYR A 596
TYR A  83
ILE A 593
ASP A 101
 None
 1.25A 2x45B-2obeA:
undetectable		 2x45B-2obeA:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 10 GLY A 690
ASP A 689
THR A 668
LEU A 663
THR A 661
 None
 1.32A 3bexA-2obeA:
undetectable
3bexB-2obeA:
undetectable		 3bexA-2obeA:
13.62
3bexB-2obeA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 11 GLY A 690
ASP A 689
THR A 668
LEU A 663
THR A 661
 None
 1.33A 3bexC-2obeA:
undetectable
3bexD-2obeA:
undetectable		 3bexC-2obeA:
13.62
3bexD-2obeA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 11 THR A 668
LEU A 663
THR A 661
GLY A 690
ASP A 689
 None
 1.32A 3bexE-2obeA:
undetectable
3bexF-2obeA:
undetectable		 3bexE-2obeA:
13.62
3bexF-2obeA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 11 GLY A 690
ASP A 689
THR A 668
LEU A 663
THR A 661
 None
 1.32A 3bf1A-2obeA:
undetectable
3bf1B-2obeA:
undetectable		 3bf1A-2obeA:
13.62
3bf1B-2obeA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 11 GLY A 690
ASP A 689
THR A 668
LEU A 663
THR A 661
 None
 1.35A 3bf1C-2obeA:
undetectable
3bf1D-2obeA:
undetectable		 3bf1C-2obeA:
13.62
3bf1D-2obeA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 11 THR A 668
LEU A 663
THR A 661
GLY A 690
ASP A 689
 None
 1.32A 3bf1C-2obeA:
undetectable
3bf1D-2obeA:
undetectable		 3bf1C-2obeA:
13.62
3bf1D-2obeA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 11 GLY A 690
ASP A 689
THR A 668
LEU A 663
THR A 661
 None
 1.32A 3bf1E-2obeA:
undetectable
3bf1F-2obeA:
undetectable		 3bf1E-2obeA:
13.62
3bf1F-2obeA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 11 THR A 668
LEU A 663
THR A 661
GLY A 690
ASP A 689
 None
 1.34A 3bf1E-2obeA:
undetectable
3bf1F-2obeA:
undetectable		 3bf1E-2obeA:
13.62
3bf1F-2obeA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_1
(PHOSPHOLIPASE A2)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 5 VAL A 372
GLN A 574
ARG A 361
ARG A 311
 None
 1.32A 3bjwE-2obeA:
undetectable		 3bjwE-2obeA:
7.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 2obe HEXON
(Human
mastadenovirus
E) 		3 / 3 PHE A 774
CYH A 846
PHE A 844
 None
 1.09A 3cr5X-2obeA:
undetectable		 3cr5X-2obeA:
5.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 2obe HEXON
(Human
mastadenovirus
E) 		3 / 3 MET A 750
MET A 850
PHE A 778
 None
 1.26A 3gn8A-2obeA:
undetectable		 3gn8A-2obeA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 8 LEU A 317
ARG A 526
ILE A 540
PHE A 310
 None
 0.91A 3ln1A-2obeA:
undetectable		 3ln1A-2obeA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 7 LEU A 317
ARG A 526
ILE A 540
PHE A 310
 None
 0.91A 3ln1B-2obeA:
undetectable		 3ln1B-2obeA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2obe HEXON
(Human
mastadenovirus
E) 		3 / 3 VAL A 836
SER A 838
LEU A 830
 None
 0.67A 3n8xA-2obeA:
undetectable		 3n8xA-2obeA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 2obe HEXON
(Human
mastadenovirus
E) 		3 / 3 TYR A  77
TYR A 319
GLU A  73
 None
 0.99A 3pfgA-2obeA:
undetectable		 3pfgA-2obeA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 7 ASN A 594
ILE A 593
PHE A 565
MET A 318
 None
 1.03A 3tvxB-2obeA:
undetectable		 3tvxB-2obeA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 2obe HEXON
(Human
mastadenovirus
E) 		3 / 3 LEU A 353
MET A 771
ASP A 847
 None
2HP  A1620 (-4.4A)
None
 0.85A 3v5wA-2obeA:
undetectable		 3v5wA-2obeA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 8 ILE A 165
LEU A 167
VAL A 188
GLY A 189
 None
 0.76A 3w1wA-2obeA:
undetectable		 3w1wA-2obeA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC392_1
(TETX2 PROTEIN)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 12 GLU A 185
VAL A 266
ILE A 165
TYR A 268
GLU A 270
 None
 1.22A 4a99A-2obeA:
undetectable
4a99C-2obeA:
undetectable		 4a99A-2obeA:
17.49
4a99C-2obeA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1103_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 5 ASN A 579
ARG A 304
MET A 484
LEU A 474
 None
 1.22A 4g5jA-2obeA:
undetectable		 4g5jA-2obeA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 7 VAL A 899
ALA A 629
LEU A 633
LEU A 353
 None
 0.72A 4l9iA-2obeA:
undetectable		 4l9iA-2obeA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 12 ASN A 306
GLY A 309
ILE A 572
GLY A 316
ASN A 570
 None
 1.20A 4obwA-2obeA:
undetectable		 4obwA-2obeA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 11 GLY A 672
PHE A 679
ASP A 568
TYR A 681
PRO A 669
 None
None
None
MPD  A1704 ( 4.7A)
None
 1.33A 4rtrA-2obeA:
undetectable		 4rtrA-2obeA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 11 GLY A 672
PHE A 679
TYR A 681
ASP A 676
PRO A 669
 None
None
MPD  A1704 ( 4.7A)
None
None
 1.32A 4rtrA-2obeA:
undetectable		 4rtrA-2obeA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 12 THR A 609
THR A 606
ALA A 607
ALA A 603
ASN A  90
 None
None
None
2HP  A1602 (-4.3A)
None
 1.45A 4u15B-2obeA:
undetectable		 4u15B-2obeA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 6 TYR A 351
LYS A 545
GLU A 348
TYR A 320
 None
 1.38A 4z4cA-2obeA:
undetectable		 4z4cA-2obeA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 4 TYR A 351
LYS A 545
GLU A 348
TYR A 320
 None
 1.42A 4z4iA-2obeA:
0.0		 4z4iA-2obeA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 5 PHE A 925
HIS A 879
LEU A 881
PRO A 924
 None
 1.29A 5csyB-2obeA:
undetectable		 5csyB-2obeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 4 LEU A 317
ARG A 526
ILE A 540
PHE A 310
 None
 0.89A 5kirB-2obeA:
undetectable		 5kirB-2obeA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 5 PHE A 112
SER A 111
ASN A 520
ASP A 373
 None
 1.38A 5kpcA-2obeA:
undetectable		 5kpcA-2obeA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 10 LEU A 554
GLY A 331
GLY A 914
ILE A 549
ALA A 338
 None
 1.03A 5l0zB-2obeA:
undetectable		 5l0zB-2obeA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 9 ALA A 548
ILE A 549
TYR A 920
ILE A 916
LEU A 329
 None
 1.06A 5mvmA-2obeA:
undetectable
5mvmE-2obeA:
undetectable		 5mvmA-2obeA:
7.78
5mvmE-2obeA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 2obe HEXON
(Human
mastadenovirus
E) 		3 / 3 THR A 362
PRO A 377
ARG A 380
 2HP  A1620 (-4.7A)
None
None
 0.80A 5nd7B-2obeA:
undetectable		 5nd7B-2obeA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 12 LEU A 896
PHE A 660
VAL A 898
ALA A 630
TRP A 652
 None
 0.97A 5tzoB-2obeA:
undetectable		 5tzoB-2obeA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 2obe HEXON
(Human
mastadenovirus
E) 		3 / 3 HIS A 517
SER A 576
ARG A 524
 None
 1.01A 5u63A-2obeA:
undetectable		 5u63A-2obeA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 5 PRO A 216
GLY A 127
TYR A 218
VAL A 282
 None
 0.94A 5x80C-2obeA:
undetectable
5x80D-2obeA:
undetectable		 5x80C-2obeA:
9.98
5x80D-2obeA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 2obe HEXON
(Human
mastadenovirus
E) 		3 / 3 GLU A 886
ASP A 888
PRO A 889
 None
 0.70A 6berA-2obeA:
undetectable		 6berA-2obeA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE SIGMA
FACTOR SIGA)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 4 LEU A 688
ASP A 689
GLN A 352
VAL A  81
 None
 1.39A 6bzoF-2obeA:
undetectable		 6bzoF-2obeA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 6 PHE A 925
ARG A 922
MET A 632
ASN A 631
 None
 1.44A 6dhbA-2obeA:
undetectable		 6dhbA-2obeA:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 2obe HEXON
(Human
mastadenovirus
E) 		4 / 7 ASP A 373
ASP A 689
GLN A 574
TYR A 364
 None
 1.48A 6g31G-2obeA:
undetectable		 6g31G-2obeA:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 2obe HEXON
(Human
mastadenovirus
E) 		5 / 11 VAL A 902
GLY A 657
ALA A 752
ASN A 631
VAL A 899
 None
 1.38A 6hu9A-2obeA:
undetectable
6hu9E-2obeA:
undetectable
6hu9I-2obeA:
undetectable		 6hu9A-2obeA:
19.25
6hu9E-2obeA:
12.04
6hu9I-2obeA:
5.97