SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2obn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 2obn HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 11 VAL A 157
GLY A 158
THR A 159
ILE A 282
VAL A 281
 None
 1.12A 1phgA-2obnA:
undetectable		 1phgA-2obnA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2obn HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 12 THR A 287
GLY A 292
GLY A 293
GLY A 296
ARG A 249
 None
 1.22A 1wg8A-2obnA:
undetectable		 1wg8A-2obnA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 2obn HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 12 MET A 194
THR A 111
LEU A 109
VAL A 132
LEU A  12
 None
 1.35A 1wsvB-2obnA:
undetectable		 1wsvB-2obnA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2obn HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 12 THR A 111
VAL A  77
ILE A  78
TYR A  91
THR A  24
 None
 1.36A 3elzC-2obnA:
undetectable		 3elzC-2obnA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 2obn HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		4 / 6 ILE A  40
LEU A  76
GLU A  66
ALA A 101
 None
 0.85A 3r9sA-2obnA:
undetectable		 3r9sA-2obnA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 2obn HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		4 / 6 ILE A  40
LEU A  76
GLU A  66
ALA A 101
 None
 0.83A 3r9sC-2obnA:
undetectable		 3r9sC-2obnA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 2obn HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		4 / 6 GLY A  16
GLU A  15
GLN A 190
MET A 194
 None
 1.15A 4g0vB-2obnA:
undetectable		 4g0vB-2obnA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 2obn HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 10 THR A 322
LEU A 305
THR A 159
VAL A 281
ILE A 282
 None
 1.17A 4jx1B-2obnA:
undetectable		 4jx1B-2obnA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 2obn HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 12 PRO A  35
ARG A  57
ALA A  27
GLY A  25
LEU A  26
 None
 1.46A 4oadA-2obnA:
undetectable		 4oadA-2obnA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 2obn HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 10 GLY A  25
ASP A  41
ILE A  55
LEU A  29
LEU A  26
 None
 1.22A 4xj7A-2obnA:
3.7
4xj7B-2obnA:
4.2		 4xj7A-2obnA:
23.90
4xj7B-2obnA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2obn HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		4 / 5 ARG A 249
GLN A 252
PRO A 253
ILE A 248
 None
 1.47A 4z4hA-2obnA:
undetectable		 4z4hA-2obnA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 2obn HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 10 ILE A 129
LEU A  99
VAL A  65
ILE A  78
LEU A  12
 None
 1.13A 5ienB-2obnA:
undetectable		 5ienB-2obnA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 2obn HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 12 ILE A 129
VAL A  75
GLU A  66
ALA A  38
ALA A  10
 None
 1.10A 5igjA-2obnA:
undetectable		 5igjA-2obnA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 2obn HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 12 LEU A 155
THR A 188
GLU A 231
VAL A 259
LEU A 247
 None
 1.41A 5jo9A-2obnA:
4.6		 5jo9A-2obnA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 2obn HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 12 VAL A  77
LEU A 170
THR A 188
GLY A 189
MET A 217
 None
 1.13A 6brdA-2obnA:
2.4		 6brdA-2obnA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 2obn HYPOTHETICAL PROTEIN
(Trichormus
variabilis) 		5 / 12 VAL A 106
LEU A 170
THR A 188
GLY A 189
MET A 217
 None
 1.10A 6brdA-2obnA:
2.4		 6brdA-2obnA:
16.29