SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2obp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 2obp PUTATIVE DNA-BINDING
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 5 VAL A  69
GLY A  75
VAL A  67
TRP A  36
 None
NO3  A  96 (-3.6A)
None
None
 1.34A 1tkqB-2obpA:
undetectable		 1tkqB-2obpA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2obp PUTATIVE DNA-BINDING
PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 8 GLY A  28
GLU A  30
ASN A  31
ALA A  84
 None
 0.87A 3aodA-2obpA:
undetectable		 3aodA-2obpA:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2obp PUTATIVE DNA-BINDING
PROTEIN
(Cupriavidus
pinatubonensis) 		3 / 3 SER A  37
ALA A  77
VAL A  67
 None
 0.68A 4o2bC-2obpA:
undetectable		 4o2bC-2obpA:
13.03