SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oby'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		4 / 8 GLY A 243
GLY A 242
MET A 241
LEU A 240
 None
NAP  A1400 (-3.3A)
NAP  A1400 (-3.3A)
None
 0.66A 1qzzA-2obyA:
7.3		 1qzzA-2obyA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		4 / 7 LEU A 286
PHE A 289
THR A 127
LEU A 126
 None
None
NAP  A1400 (-3.2A)
None
 1.09A 2eikA-2obyA:
undetectable
2eikJ-2obyA:
undetectable		 2eikA-2obyA:
21.43
2eikJ-2obyA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 12 ALA A  38
ILE A 326
SER A  66
ALA A  96
ASP A  43
 None
 1.20A 2ejtA-2obyA:
8.5		 2ejtA-2obyA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 11 ILE A 213
LEU A 145
GLY A 189
ALA A 188
GLY A 185
 None
 1.14A 2fxdA-2obyA:
undetectable		 2fxdA-2obyA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_CCSB417_0
(ESTROGEN RECEPTOR)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		3 / 3 GLN A  97
LYS A  22
VAL A  20
 None
 0.92A 2jfaB-2obyA:
undetectable		 2jfaB-2obyA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		6 / 12 GLY A 218
GLY A 243
ILE A 246
ASP A 245
LEU A 237
LEU A 261
 None
 1.04A 2nxeA-2obyA:
10.9		 2nxeA-2obyA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 12 GLY A 218
ILE A 246
ASP A 245
LEU A 237
LEU A 261
 None
 0.95A 2nxeB-2obyA:
11.1		 2nxeB-2obyA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 12 GLY A 218
ILE A 246
ASP A 245
LEU A 237
LEU A 261
 None
 0.92A 2zbpA-2obyA:
10.7		 2zbpA-2obyA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 12 ALA A  38
ILE A 326
SER A  66
ALA A  96
ASP A  43
 None
 1.21A 3axtA-2obyA:
7.4		 3axtA-2obyA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 12 GLY A 218
ILE A 246
ASP A 245
LEU A 237
LEU A 261
 None
 0.91A 3cjtC-2obyA:
11.3		 3cjtC-2obyA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 12 GLY A 218
GLY A 243
ASP A 245
LEU A 237
LEU A 261
 None
 1.09A 3cjtG-2obyA:
11.3		 3cjtG-2obyA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 12 GLY A 218
ILE A 246
ASP A 245
LEU A 237
LEU A 261
 None
 0.92A 3cjtG-2obyA:
11.3		 3cjtG-2obyA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 12 GLY A 218
ILE A 246
ASP A 245
LEU A 237
LEU A 261
 None
 0.92A 3cjtK-2obyA:
11.3		 3cjtK-2obyA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		6 / 12 GLY A 218
GLY A 243
ILE A 246
ASP A 245
LEU A 237
LEU A 261
 None
 1.08A 3cjtO-2obyA:
11.4		 3cjtO-2obyA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 12 PRO A  91
GLY A  92
GLY A  93
LEU A 126
ILE A 121
 None
 0.95A 3douA-2obyA:
9.2		 3douA-2obyA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 11 LEU A 145
GLY A 189
ALA A 188
ILE A 167
GLY A 185
 None
 0.90A 3ebzB-2obyA:
undetectable		 3ebzB-2obyA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 11 HIS A 314
LEU A  39
GLN A  46
GLY A  62
GLY A  94
 None
 1.20A 3gy3A-2obyA:
undetectable		 3gy3A-2obyA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 12 GLY A  62
GLN A  95
LEU A  39
MET A 317
LEU A  44
 None
None
None
NAP  A1400 (-3.6A)
None
 1.48A 3h52D-2obyA:
undetectable		 3h52D-2obyA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 11 VAL A 144
ILE A 158
GLY A 154
ALA A 157
LEU A 132
 None
 1.19A 3n8yA-2obyA:
undetectable		 3n8yA-2obyA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		4 / 5 GLU A  64
LEU A  90
GLN A  95
GLY A  93
 None
 1.29A 3pp1A-2obyA:
undetectable		 3pp1A-2obyA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 10 LEU A 145
GLY A 189
ALA A 188
ILE A 167
GLY A 185
 None
 0.99A 3s43B-2obyA:
undetectable		 3s43B-2obyA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 11 LEU A 145
GLY A 189
ALA A 188
ILE A 167
GLY A 185
 None
 0.89A 3s45B-2obyA:
undetectable		 3s45B-2obyA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_1
(PROTEASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 12 LEU A 145
GLY A 189
ALA A 188
ILE A 167
GLY A 185
 None
 0.99A 3ucbA-2obyA:
undetectable		 3ucbA-2obyA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 12 LEU A 145
GLY A 189
ALA A 188
ILE A 167
GLY A 185
 None
 1.02A 3ucbB-2obyA:
undetectable		 3ucbB-2obyA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		4 / 7 GLY A 141
ALA A 166
ALA A 187
ARG A 162
 None
 0.82A 3ur0B-2obyA:
undetectable		 3ur0B-2obyA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		4 / 5 LEU A  63
ARG A 267
PRO A  53
ALA A  57
 None
 1.31A 3vm4A-2obyA:
undetectable		 3vm4A-2obyA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		4 / 5 ASP A  43
GLU A  64
GLY A  62
GLN A  46
 None
 1.21A 3w9tB-2obyA:
undetectable		 3w9tB-2obyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		4 / 5 ASP A  43
GLU A  64
GLY A  62
GLN A  46
 None
 1.18A 3w9tD-2obyA:
undetectable		 3w9tD-2obyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		4 / 5 ASP A  43
GLU A  64
GLY A  62
GLN A  46
 None
 1.24A 3w9tE-2obyA:
undetectable		 3w9tE-2obyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		4 / 5 ASP A  43
GLU A  64
GLY A  62
GLN A  46
 None
 1.29A 3w9tG-2obyA:
undetectable		 3w9tG-2obyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 12 ALA A 120
ILE A 326
ASN A 322
GLY A 324
ASN A  40
 None
None
NAP  A1400 (-3.6A)
None
None
 1.24A 4obwD-2obyA:
7.1		 4obwD-2obyA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 10 LEU A 145
GLY A 189
ALA A 188
ILE A 167
GLY A 185
 None
 0.95A 4q1yA-2obyA:
undetectable		 4q1yA-2obyA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 12 ALA A  42
ARG A 267
ALA A  96
GLY A  93
GLU A  64
 None
 1.23A 4r29C-2obyA:
undetectable		 4r29C-2obyA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		5 / 10 GLY A  62
GLN A  95
LEU A 330
ALA A  36
ALA A 120
 None
 1.08A 4wnuD-2obyA:
undetectable		 4wnuD-2obyA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens) 		4 / 6 SER A 151
ALA A 157
THR A 161
ALA A 186
 NAP  A1400 (-3.7A)
None
None
None
 1.13A 6ma6A-2obyA:
undetectable		 6ma6A-2obyA:
15.85