SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ocd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 7 ILE A  15
GLU A  32
PHE A  41
ALA A  36
 None
 1.16A 1oniD-2ocdA:
undetectable
1oniE-2ocdA:
undetectable		 1oniD-2ocdA:
17.54
1oniE-2ocdA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		5 / 11 VAL A 205
PHE A 105
LEU A 101
ILE A 208
GLN A  69
 None
 1.06A 1uduA-2ocdA:
undetectable		 1uduA-2ocdA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		5 / 12 ILE A 239
LEU A 240
ALA A 306
GLY A 298
SER A 297
 None
 1.07A 2a58D-2ocdA:
5.1
2a58E-2ocdA:
2.9		 2a58D-2ocdA:
17.86
2a58E-2ocdA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 7 LEU A 149
THR A 115
GLY A 128
ASP A 127
 None
 0.99A 2ddwB-2ocdA:
undetectable		 2ddwB-2ocdA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 5 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 1.19A 2eimJ-2ocdA:
undetectable		 2eimJ-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 5 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 1.25A 2eimW-2ocdA:
undetectable		 2eimW-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		5 / 11 VAL A 205
PHE A 105
LEU A 101
ILE A 208
GLN A  69
 None
 1.22A 2h42A-2ocdA:
undetectable		 2h42A-2ocdA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 8 MET A  38
PHE A  41
ALA A 130
LEU A 133
 None
 1.09A 2o01A-2ocdA:
undetectable		 2o01A-2ocdA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_A_DAHA2_1
(RANASMURFIN)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		5 / 9 ALA A  95
ALA A  98
SER A 102
PHE A 103
ALA A 305
 None
 1.20A 2vh3A-2ocdA:
undetectable		 2vh3A-2ocdA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 5 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 1.04A 3ag1J-2ocdA:
undetectable		 3ag1J-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 6 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 0.96A 3ag1N-2ocdA:
undetectable
3ag1W-2ocdA:
undetectable		 3ag1N-2ocdA:
20.19
3ag1W-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 5 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 1.26A 3ag2J-2ocdA:
undetectable		 3ag2J-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 5 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 1.09A 3ag4J-2ocdA:
undetectable		 3ag4J-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		5 / 11 ASP A  73
ALA A 100
PHE A 105
PHE A 203
ILE A 208
 None
 1.43A 3n23A-2ocdA:
undetectable		 3n23A-2ocdA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		5 / 11 VAL A 269
LEU A 271
THR A 272
GLU A 334
ALA A 306
 None
 1.16A 4e0fA-2ocdA:
undetectable		 4e0fA-2ocdA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		5 / 11 ARG A 157
VAL A 193
SER A 190
LEU A 189
LEU A 177
 None
 1.20A 4or0B-2ocdA:
undetectable		 4or0B-2ocdA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 5 LEU A 313
ALA A 308
VAL A 269
ILE A 239
 None
 0.98A 4xe3A-2ocdA:
undetectable		 4xe3A-2ocdA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 5 TYR A 312
ILE A 208
LEU A 108
PHE A 105
 None
 0.90A 5kmdC-2ocdA:
undetectable
5kmdD-2ocdA:
undetectable		 5kmdC-2ocdA:
21.53
5kmdD-2ocdA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 7 TYR A   7
ILE A   8
ILE A   6
ILE A 113
 None
 0.93A 5murB-2ocdA:
undetectable		 5murB-2ocdA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 5 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 1.27A 5w97J-2ocdA:
undetectable		 5w97J-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 5 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 1.08A 5wauJ-2ocdA:
undetectable		 5wauJ-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 5 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 1.05A 5x19J-2ocdA:
undetectable		 5x19J-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 5 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 1.05A 5x1bJ-2ocdA:
undetectable		 5x1bJ-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 5 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 1.05A 5x1bW-2ocdA:
undetectable		 5x1bW-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 6 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 1.00A 5x1fA-2ocdA:
undetectable
5x1fJ-2ocdA:
undetectable		 5x1fA-2ocdA:
20.19
5x1fJ-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 5 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 1.12A 5x1fW-2ocdA:
undetectable		 5x1fW-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 5 TYR A  10
TYR A  54
GLY A  12
GLY A  13
 None
None
None
ACT  A 601 ( 4.0A)
 0.89A 5x7pA-2ocdA:
undetectable		 5x7pA-2ocdA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 6 TYR A  10
TYR A  54
GLY A  12
GLY A  13
 None
None
None
ACT  A 601 ( 4.0A)
 0.90A 5x7pB-2ocdA:
undetectable		 5x7pB-2ocdA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 5 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 1.00A 6nknJ-2ocdA:
undetectable		 6nknJ-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 5 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 1.30A 6nknW-2ocdA:
undetectable		 6nknW-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ocd L-ASPARAGINASE I
(Vibrio
cholerae) 		4 / 7 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 0.95A 6nmpA-2ocdA:
undetectable
6nmpJ-2ocdA:
undetectable		 6nmpA-2ocdA:
20.19
6nmpJ-2ocdA:
11.04