SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ocx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 2ocx NODULATION
FUCOSYLTRANSFERASE
NODZ
(Bradyrhizobium
sp.
WM9) 		4 / 7 PHE A  58
SER A  43
PHE A  15
ALA A  53
 None
 1.13A 1fxvA-2ocxA:
undetectable
1fxvB-2ocxA:
undetectable		 1fxvA-2ocxA:
20.07
1fxvB-2ocxA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 2ocx NODULATION
FUCOSYLTRANSFERASE
NODZ
(Bradyrhizobium
sp.
WM9) 		4 / 8 LEU A 198
VAL A 201
VAL A 239
VAL A 219
 None
 0.90A 1iwiA-2ocxA:
undetectable		 1iwiA-2ocxA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2ocx NODULATION
FUCOSYLTRANSFERASE
NODZ
(Bradyrhizobium
sp.
WM9) 		3 / 3 ASN A  52
ARG A  41
ASP A 129
 None
 0.69A 2qe6A-2ocxA:
2.7		 2qe6A-2ocxA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2ocx NODULATION
FUCOSYLTRANSFERASE
NODZ
(Bradyrhizobium
sp.
WM9) 		3 / 3 ASN A  52
ARG A  41
ASP A 129
 None
 0.69A 2qe6B-2ocxA:
2.8		 2qe6B-2ocxA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 2ocx NODULATION
FUCOSYLTRANSFERASE
NODZ
(Bradyrhizobium
sp.
WM9) 		4 / 7 VAL A 219
ILE A 205
ALA A 208
GLY A 173
 None
 0.76A 2xrzB-2ocxA:
undetectable		 2xrzB-2ocxA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2ocx NODULATION
FUCOSYLTRANSFERASE
NODZ
(Bradyrhizobium
sp.
WM9) 		4 / 6 LEU A 198
VAL A 201
VAL A 239
VAL A 219
 None
 0.94A 2z97A-2ocxA:
undetectable		 2z97A-2ocxA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 2ocx NODULATION
FUCOSYLTRANSFERASE
NODZ
(Bradyrhizobium
sp.
WM9) 		5 / 9 VAL A 174
ILE A 205
ALA A 197
VAL A 228
VAL A 232
 None
 1.24A 3me6C-2ocxA:
undetectable		 3me6C-2ocxA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 2ocx NODULATION
FUCOSYLTRANSFERASE
NODZ
(Bradyrhizobium
sp.
WM9) 		4 / 6 ILE A 301
VAL A 201
LEU A 198
CYH A 202
 None
 0.92A 4asdA-2ocxA:
undetectable		 4asdA-2ocxA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 2ocx NODULATION
FUCOSYLTRANSFERASE
NODZ
(Bradyrhizobium
sp.
WM9) 		4 / 5 GLU A 141
SER A  21
ARG A 291
SER A  24
 None
 1.17A 4k17B-2ocxA:
undetectable		 4k17B-2ocxA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2ocx NODULATION
FUCOSYLTRANSFERASE
NODZ
(Bradyrhizobium
sp.
WM9) 		4 / 7 ASN A 124
PRO A  81
PHE A   6
TYR A  28
 None
PO4  A 332 ( 4.8A)
PO4  A 332 (-4.7A)
None
 1.17A 5amkB-2ocxA:
undetectable		 5amkB-2ocxA:
18.75