SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2od4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZJQ_A_NCAA300_0 (PROTOGLOBIN)	2od4	HYPOTHETICAL PROTEIN (uncultured marine organism)	4 / 7	TYR A 58 VAL A 13 VAL A 38 ILE A 10	EDO A 103 ( 4.9A) None None None	0.98A	3zjqA-2od4A: undetectable	3zjqA-2od4A: 19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZJQ_B_NCAB300_0 (PROTOGLOBIN)	2od4	HYPOTHETICAL PROTEIN (uncultured marine organism)	4 / 7	TYR A 58 VAL A 13 VAL A 38 ILE A 10	EDO A 103 ( 4.9A) None None None	0.98A	3zjqB-2od4A: undetectable	3zjqB-2od4A: 19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKX_C_STRC601_2 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	2od4	HYPOTHETICAL PROTEIN (uncultured marine organism)	4 / 5	ILE A 75 ARG A 83 GLU A 78 VAL A 33	None CL A 102 (-3.2A) None None	1.19A	4nkxC-2od4A: undetectable	4nkxC-2od4A: 14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKX_D_STRD601_2 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	2od4	HYPOTHETICAL PROTEIN (uncultured marine organism)	4 / 5	ILE A 75 ARG A 83 GLU A 78 VAL A 33	None CL A 102 (-3.2A) None None	1.13A	4nkxD-2od4A: undetectable	4nkxD-2od4A: 14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0S_B_SAMB501_0 (PEPTIDE N-METHYLTRANSFERASE)	2od4	HYPOTHETICAL PROTEIN (uncultured marine organism)	5 / 12	ILE A 60 VAL A 79 VAL A 82 ILE A 39 ALA A 43	CL A 101 ( 4.0A) None None None None	1.16A	5n0sB-2od4A: undetectable	5n0sB-2od4A: 15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0W_B_SAMB501_0 (PEPTIDE N-METHYLTRANSFERASE)	2od4	HYPOTHETICAL PROTEIN (uncultured marine organism)	5 / 12	ILE A 60 VAL A 79 VAL A 82 ILE A 39 ALA A 43	CL A 101 ( 4.0A) None None None None	1.09A	5n0wB-2od4A: undetectable	5n0wB-2od4A: 15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N4I_A_SAMA501_0 (PEPTIDE N-METHYLTRANSFERASE)	2od4	HYPOTHETICAL PROTEIN (uncultured marine organism)	5 / 12	ILE A 60 VAL A 79 VAL A 82 ILE A 39 ALA A 43	CL A 101 ( 4.0A) None None None None	1.07A	5n4iA-2od4A: undetectable	5n4iA-2od4A: 15.30

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ZJQ_A_NCAA300_0","PROTOGLOBIN","2od4","HYPOTHETICAL PROTEIN","uncultured marine organism",4,"TYR A  58;VAL A  13;VAL A  38;ILE A  10","EDO A 103 ( 4.9A);None;None;None","0.98A","3zjqA-2od4A:undetectable","3zjqA-2od4A:19.07"],["3ZJQ_B_NCAB300_0","PROTOGLOBIN","2od4","HYPOTHETICAL PROTEIN","uncultured marine organism",4,"TYR A  58;VAL A  13;VAL A  38;ILE A  10","EDO A 103 ( 4.9A);None;None;None","0.98A","3zjqB-2od4A:undetectable","3zjqB-2od4A:19.07"],["4NKX_C_STRC601_2","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","2od4","HYPOTHETICAL PROTEIN","uncultured marine organism",4,"ILE A  75;ARG A  83;GLU A  78;VAL A  33","None; CL A 102 (-3.2A);None;None","1.19A","4nkxC-2od4A:undetectable","4nkxC-2od4A:14.63"],["4NKX_D_STRD601_2","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","2od4","HYPOTHETICAL PROTEIN","uncultured marine organism",4,"ILE A  75;ARG A  83;GLU A  78;VAL A  33","None; CL A 102 (-3.2A);None;None","1.13A","4nkxD-2od4A:undetectable","4nkxD-2od4A:14.63"],["5N0S_B_SAMB501_0","PEPTIDE N-METHYLTRANSFERASE","2od4","HYPOTHETICAL PROTEIN","uncultured marine organism",5,"ILE A  60;VAL A  79;VAL A  82;ILE A  39;ALA A  43"," CL A 101 ( 4.0A);None;None;None;None","1.16A","5n0sB-2od4A:undetectable","5n0sB-2od4A:15.30"],["5N0W_B_SAMB501_0","PEPTIDE N-METHYLTRANSFERASE","2od4","HYPOTHETICAL PROTEIN","uncultured marine organism",5,"ILE A  60;VAL A  79;VAL A  82;ILE A  39;ALA A  43"," CL A 101 ( 4.0A);None;None;None;None","1.09A","5n0wB-2od4A:undetectable","5n0wB-2od4A:15.30"],["5N4I_A_SAMA501_0","PEPTIDE N-METHYLTRANSFERASE","2od4","HYPOTHETICAL PROTEIN","uncultured marine organism",5,"ILE A  60;VAL A  79;VAL A  82;ILE A  39;ALA A  43"," CL A 101 ( 4.0A);None;None;None;None","1.07A","5n4iA-2od4A:undetectable","5n4iA-2od4A:15.30"]]