SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2odf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2odf HYPOTHETICAL PROTEIN
ATU2144
(Agrobacterium
fabrum) 		4 / 4 LEU A  28
VAL A  30
CYH A  31
ALA A  34
 None
 1.22A 1mz9E-2odfA:
undetectable		 1mz9E-2odfA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 2odf HYPOTHETICAL PROTEIN
ATU2144
(Agrobacterium
fabrum) 		4 / 7 TYR A  87
MET A  99
ASP A  88
HIS A 154
 None
 1.30A 1t03A-2odfA:
undetectable		 1t03A-2odfA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2odf HYPOTHETICAL PROTEIN
ATU2144
(Agrobacterium
fabrum) 		3 / 3 ASP A  50
THR A 157
PRO A 158
 None
 0.55A 2pynB-2odfA:
undetectable		 2pynB-2odfA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 2odf HYPOTHETICAL PROTEIN
ATU2144
(Agrobacterium
fabrum) 		3 / 3 ASP A  50
THR A 157
PRO A 158
 None
 0.48A 2q64B-2odfA:
undetectable		 2q64B-2odfA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 2odf HYPOTHETICAL PROTEIN
ATU2144
(Agrobacterium
fabrum) 		3 / 3 ASP A  50
THR A 157
PRO A 158
 None
 0.57A 2qakB-2odfA:
undetectable		 2qakB-2odfA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2odf HYPOTHETICAL PROTEIN
ATU2144
(Agrobacterium
fabrum) 		5 / 12 ILE A  38
GLY A  43
TYR A  42
GLY A  46
LEU A  47
 None
 0.98A 2y7kD-2odfA:
undetectable		 2y7kD-2odfA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 2odf HYPOTHETICAL PROTEIN
ATU2144
(Agrobacterium
fabrum) 		5 / 12 ALA A  56
LEU A  52
SER A  53
SER A 103
TYR A 106
 None
 1.21A 3bxoA-2odfA:
undetectable		 3bxoA-2odfA:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_0
(N,N-DIMETHYLTRANSFER
ASE)		 2odf HYPOTHETICAL PROTEIN
ATU2144
(Agrobacterium
fabrum) 		5 / 12 ALA A  56
LEU A  52
SER A  53
SER A 103
TYR A 106
 None
 1.17A 3bxoB-2odfA:
undetectable		 3bxoB-2odfA:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 2odf HYPOTHETICAL PROTEIN
ATU2144
(Agrobacterium
fabrum) 		3 / 3 ASP A  50
THR A 157
PRO A 158
 None
 0.38A 3tkgD-2odfA:
undetectable		 3tkgD-2odfA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2odf HYPOTHETICAL PROTEIN
ATU2144
(Agrobacterium
fabrum) 		4 / 6 ILE A  38
PHE A   8
HIS A  33
VAL A  78
 None
 1.21A 4a97I-2odfA:
undetectable		 4a97I-2odfA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 2odf HYPOTHETICAL PROTEIN
ATU2144
(Agrobacterium
fabrum) 		5 / 8 ILE A 153
LEU A  69
ILE A 169
LYS A 250
GLY A 249
 None
 1.50A 4hb6A-2odfA:
undetectable		 4hb6A-2odfA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2odf HYPOTHETICAL PROTEIN
ATU2144
(Agrobacterium
fabrum) 		5 / 8 ILE A 153
LEU A  69
ILE A 169
LYS A 250
GLY A 249
 None
 1.26A 4hb8A-2odfA:
undetectable		 4hb8A-2odfA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 2odf HYPOTHETICAL PROTEIN
ATU2144
(Agrobacterium
fabrum) 		4 / 7 ILE A 153
LEU A  69
LYS A 250
GLY A 249
 None
 1.07A 4hbfA-2odfA:
undetectable		 4hbfA-2odfA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 2odf HYPOTHETICAL PROTEIN
ATU2144
(Agrobacterium
fabrum) 		5 / 9 LEU A 179
GLY A 249
VAL A 149
VAL A 151
LEU A  29
 None
 0.94A 4qd3A-2odfA:
3.8		 4qd3A-2odfA:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 2odf HYPOTHETICAL PROTEIN
ATU2144
(Agrobacterium
fabrum) 		5 / 12 VAL A 194
PHE A 243
LEU A  29
VAL A  27
GLY A 242
 None
 1.20A 6brdA-2odfA:
undetectable		 6brdA-2odfA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 2odf HYPOTHETICAL PROTEIN
ATU2144
(Agrobacterium
fabrum) 		4 / 5 ASN A  90
GLY A 170
HIS A 154
ASP A  59
 None
 1.11A 6gh9A-2odfA:
undetectable		 6gh9A-2odfA:
14.81