SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2odl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 9 LEU A 343
VAL A 381
ILE A 403
VAL A 392
ILE A 391
 None
 1.32A 1gebA-2odlA:
undetectable		 1gebA-2odlA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 2odl ADHESIN
(Haemophilus
influenzae) 		4 / 8 ASN A 126
LEU A 140
LEU A  71
SER A 134
 None
 1.11A 1hk3A-2odlA:
undetectable		 1hk3A-2odlA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		4 / 7 VAL A 211
SER A 210
ASN A 246
ASP A 208
 None
 1.33A 1hwiC-2odlA:
undetectable		 1hwiC-2odlA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		4 / 7 VAL A 211
SER A 210
ASN A 246
ASP A 208
 None
 1.33A 1hwiD-2odlA:
undetectable		 1hwiD-2odlA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 9 GLY A 354
ASP A 356
GLY A 422
VAL A 418
ILE A 391
 None
 1.12A 1hxwA-2odlA:
undetectable		 1hxwA-2odlA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 12 VAL A 333
LEU A 367
SER A 421
THR A 329
GLU A 357
 None
 1.22A 1kw0A-2odlA:
undetectable		 1kw0A-2odlA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 11 VAL A 333
LEU A 367
SER A 421
THR A 329
GLU A 357
 None
 1.25A 1mmtA-2odlA:
undetectable		 1mmtA-2odlA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_1
(ASPARTYLPROTEASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		6 / 11 GLY A 270
ALA A 288
ASP A 289
GLY A 323
VAL A 300
ILE A 299
 None
 1.43A 1ohrA-2odlA:
undetectable		 1ohrA-2odlA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 2odl ADHESIN
(Haemophilus
influenzae) 		4 / 5 ILE A  99
ILE A 154
ILE A 174
LEU A  71
 None
 0.80A 1zgyA-2odlA:
undetectable		 1zgyA-2odlA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 2odl ADHESIN
(Haemophilus
influenzae) 		4 / 5 ILE A 149
ILE A  92
ILE A  99
LEU A 136
 None
 0.94A 1zgyA-2odlA:
undetectable		 1zgyA-2odlA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 2odl ADHESIN
(Haemophilus
influenzae) 		6 / 12 GLY A 270
ALA A 288
ASP A 289
GLY A 323
VAL A 300
ILE A 299
 None
 1.44A 2avoB-2odlA:
undetectable		 2avoB-2odlA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		6 / 12 GLY A 270
ALA A 288
ASP A 289
GLY A 323
VAL A 300
ILE A 299
 None
 1.38A 2bpxB-2odlA:
undetectable		 2bpxB-2odlA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		4 / 7 ASP A 294
SER A 290
ASN A 318
GLN A 319
 None
 0.98A 2cmlA-2odlA:
undetectable		 2cmlA-2odlA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		4 / 8 ASP A 294
SER A 290
ASN A 318
GLN A 319
 None
 0.94A 2cmlD-2odlA:
undetectable		 2cmlD-2odlA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 2odl ADHESIN
(Haemophilus
influenzae) 		4 / 6 ASN A 380
ASN A 404
ILE A 411
GLN A 406
 None
 0.93A 2hkkA-2odlA:
undetectable		 2hkkA-2odlA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		4 / 8 LEU A  71
VAL A 146
LEU A 148
VAL A 124
 None
 0.68A 2zujA-2odlA:
undetectable		 2zujA-2odlA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		4 / 7 VAL A 146
LEU A 140
ILE A 100
ASN A 126
 None
 1.05A 3avpA-2odlA:
undetectable		 3avpA-2odlA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 12 LEU A 343
GLY A 348
GLY A 383
SER A 315
GLY A 323
 None
 0.85A 3axzA-2odlA:
undetectable		 3axzA-2odlA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_1
(HIV-1 PROTEASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		6 / 12 GLY A 270
ALA A 288
ASP A 289
GLY A 323
VAL A 300
ILE A 299
 None
 1.42A 3d1yA-2odlA:
undetectable		 3d1yA-2odlA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 8 GLY A 270
ALA A 288
ASP A 289
GLY A 323
VAL A 300
 None
 1.44A 3em6A-2odlA:
undetectable		 3em6A-2odlA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		6 / 12 GLY A 270
ALA A 288
ASP A 289
GLY A 323
VAL A 300
ILE A 299
 None
 1.45A 3k4vA-2odlA:
undetectable		 3k4vA-2odlA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		6 / 12 GLY A 270
ALA A 288
ASP A 289
GLY A 323
VAL A 300
ILE A 299
 None
 1.50A 3ndtA-2odlA:
undetectable		 3ndtA-2odlA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		4 / 6 ALA A  98
ILE A 100
VAL A 146
ASN A 126
 None
 0.81A 3nneG-2odlA:
undetectable		 3nneG-2odlA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		6 / 12 GLY A 270
ALA A 288
ASP A 289
GLY A 323
VAL A 300
ILE A 299
 None
 1.45A 3tl9A-2odlA:
undetectable		 3tl9A-2odlA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 10 ILE A 203
VAL A 205
ILE A 273
ILE A 224
THR A 164
 None
 1.11A 3um5A-2odlA:
undetectable		 3um5A-2odlA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 12 ILE A 310
LEU A 301
VAL A 275
LEU A 286
ILE A 231
 None
 1.15A 4g1bD-2odlA:
undetectable		 4g1bD-2odlA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 12 LEU A 343
GLY A 348
GLY A 383
SER A 315
GLY A 323
 None
 0.83A 4yvgA-2odlA:
undetectable		 4yvgA-2odlA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 2odl ADHESIN
(Haemophilus
influenzae) 		4 / 7 GLY A 401
GLY A 376
ASP A 434
ASP A 400
 None
 0.80A 5ergB-2odlA:
undetectable		 5ergB-2odlA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 12 THR A 329
ALA A 303
LYS A 304
ALA A 254
ILE A 280
 None
 1.24A 5eypB-2odlA:
undetectable		 5eypB-2odlA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 12 GLY A 166
GLN A 145
LEU A 233
GLY A 216
THR A 171
 None
 1.19A 5fsaB-2odlA:
undetectable		 5fsaB-2odlA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 2odl ADHESIN
(Haemophilus
influenzae) 		6 / 12 GLY A 270
ALA A 288
ASP A 289
GLY A 323
VAL A 300
ILE A 299
 None
 1.34A 5kqxA-2odlA:
undetectable		 5kqxA-2odlA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 12 GLY A 387
GLY A 383
ILE A 403
ASP A 342
ALA A 390
 None
 0.88A 5l0zA-2odlA:
undetectable		 5l0zA-2odlA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 10 LEU A 353
GLY A 354
VAL A 300
LEU A 301
ARG A 276
 None
 1.15A 5o96E-2odlA:
undetectable
5o96F-2odlA:
undetectable		 5o96E-2odlA:
24.02
5o96F-2odlA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 10 LEU A 353
GLY A 355
VAL A 300
LEU A 301
ARG A 276
 None
 1.19A 5o96E-2odlA:
undetectable
5o96F-2odlA:
undetectable		 5o96E-2odlA:
24.02
5o96F-2odlA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 12 LEU A 343
GLY A 348
GLY A 383
SER A 315
GLY A 323
 None
 0.88A 5zhmB-2odlA:
undetectable		 5zhmB-2odlA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 10 GLY A 215
GLY A 216
ASN A 258
ILE A 214
ALA A 235
 None
 1.12A 6e5zA-2odlA:
undetectable		 6e5zA-2odlA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 2odl ADHESIN
(Haemophilus
influenzae) 		5 / 12 LEU A 234
ILE A 214
GLY A 215
ILE A 249
ILE A 239
 None
 0.99A 6emuA-2odlA:
undetectable		 6emuA-2odlA:
20.91