SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2odo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		4 / 7 HIS A  39
GLY A  38
ALA A  36
TYR A  37
 None
None
None
LLP  A  33 ( 4.5A)
 0.88A 1dmaA-2odoA:
undetectable		 1dmaA-2odoA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		4 / 8 LEU A 197
ALA A  20
LEU A 155
SER A 204
 None
 0.83A 1dvtA-2odoA:
undetectable
1dvtB-2odoA:
undetectable		 1dvtA-2odoA:
16.21
1dvtB-2odoA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBK_A_RAPA225_1
(FKBP25)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		5 / 12 GLY A 210
VAL A  31
ILE A  32
ALA A  73
ILE A  71
 LLP  A  33 ( 3.2A)
LLP  A  33 ( 4.6A)
LLP  A  33 ( 4.3A)
None
None
 0.98A 1pbkA-2odoA:
undetectable		 1pbkA-2odoA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		4 / 6 ASP A 124
ASP A 136
ASN A 135
GLU A 172
 None
 1.32A 1rjdA-2odoA:
undetectable		 1rjdA-2odoA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		5 / 12 GLY A 210
GLY A 215
VAL A  31
ALA A  30
LEU A  78
 LLP  A  33 ( 3.2A)
None
LLP  A  33 ( 4.6A)
None
LLP  A  33 ( 4.1A)
 0.95A 1vptA-2odoA:
undetectable		 1vptA-2odoA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_2
(PROTEASE)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		5 / 12 GLY A 315
ALA A 314
ILE A 265
VAL A 286
VAL A 288
 None
 0.72A 2ieoB-2odoA:
undetectable		 2ieoB-2odoA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		3 / 3 TRP A  96
VAL A 150
TRP A 120
 None
 1.26A 2xdcC-2odoA:
undetectable
2xdcD-2odoA:
undetectable		 2xdcC-2odoA:
4.64
2xdcD-2odoA:
4.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		3 / 3 TRP A  96
VAL A 150
TRP A 120
 None
 1.22A 2xdcE-2odoA:
undetectable
2xdcF-2odoA:
undetectable		 2xdcE-2odoA:
4.64
2xdcF-2odoA:
4.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		3 / 3 TRP A  96
VAL A 150
TRP A 120
 None
 1.26A 2y5mE-2odoA:
undetectable
2y5mF-2odoA:
undetectable		 2y5mE-2odoA:
4.64
2y5mF-2odoA:
4.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		3 / 3 TRP A  96
VAL A 150
TRP A 120
 None
 1.27A 2y6nC-2odoA:
undetectable
2y6nD-2odoA:
undetectable		 2y6nC-2odoA:
4.64
2y6nD-2odoA:
4.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		3 / 3 TRP A  96
VAL A 150
TRP A 120
 None
 1.27A 2y6nE-2odoA:
undetectable
2y6nF-2odoA:
undetectable		 2y6nE-2odoA:
4.64
2y6nF-2odoA:
4.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		5 / 12 GLY A 131
LEU A 102
ALA A 140
VAL A  98
LEU A 121
 KCX  A 122 ( 3.5A)
None
None
None
KCX  A 122 ( 3.9A)
 0.98A 2yqzA-2odoA:
undetectable		 2yqzA-2odoA:
26.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DFR_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		5 / 12 LEU A  66
ALA A  73
LEU A  29
LEU A  78
ALA A  63
 None
None
None
LLP  A  33 ( 4.1A)
None
 1.13A 3dfrA-2odoA:
undetectable		 3dfrA-2odoA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		5 / 10 GLY A 315
ALA A 314
VAL A 291
VAL A 286
VAL A 288
 None
 0.74A 3nu9B-2odoA:
undetectable		 3nu9B-2odoA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		5 / 12 LEU A 295
VAL A 286
PHE A 287
THR A 234
VAL A 268
 None
 1.28A 3sp9B-2odoA:
undetectable		 3sp9B-2odoA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		5 / 12 GLY A 315
ALA A 314
ILE A 265
VAL A 286
VAL A 288
 None
 0.88A 3ucbB-2odoA:
undetectable		 3ucbB-2odoA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		3 / 3 TRP A  96
VAL A 150
TRP A 120
 None
 1.20A 3zq8A-2odoA:
undetectable
3zq8B-2odoA:
undetectable		 3zq8A-2odoA:
4.64
3zq8B-2odoA:
4.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		4 / 6 ALA A  20
ILE A  32
GLY A 210
SER A 189
 None
LLP  A  33 ( 4.3A)
LLP  A  33 ( 3.2A)
None
 0.81A 4r21A-2odoA:
undetectable		 4r21A-2odoA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		5 / 8 ALA A  41
ALA A  36
ILE A  32
TYR A 214
LEU A 213
 None
None
LLP  A  33 ( 4.3A)
None
None
 1.39A 4v1fA-2odoA:
undetectable
4v1fB-2odoA:
undetectable		 4v1fA-2odoA:
13.12
4v1fB-2odoA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		5 / 12 TYR A  17
GLY A  54
PRO A 209
ASP A  94
ASP A  53
 None
 1.26A 5yn6A-2odoA:
undetectable		 5yn6A-2odoA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		5 / 12 TYR A  17
GLY A  54
PRO A 209
ASP A  94
ASP A  53
 None
 1.25A 5yniA-2odoA:
undetectable		 5yniA-2odoA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		5 / 12 TYR A  17
GLY A  54
PRO A 209
ASP A  94
ASP A  53
 None
 1.27A 5ynmA-2odoA:
undetectable		 5ynmA-2odoA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_0
(PROTEASE)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		5 / 12 GLY A 315
ALA A 314
VAL A 291
VAL A 286
VAL A 288
 None
 0.73A 6dh0A-2odoA:
undetectable		 6dh0A-2odoA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		5 / 12 GLY A 315
ALA A 314
ILE A 265
VAL A 286
VAL A 288
 None
 0.81A 6dh0B-2odoA:
undetectable		 6dh0B-2odoA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 2odo ALANINE RACEMASE
(Pseudomonas
fluorescens) 		5 / 12 GLY A 315
ALA A 314
VAL A 291
VAL A 286
VAL A 288
 None
 0.82A 6dh0B-2odoA:
undetectable		 6dh0B-2odoA:
14.89