SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2odp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 8 HIS A 487
SER A 659
VAL A 677
GLY A 680
 None
 0.60A 1aq7A-2odpA:
21.4		 1aq7A-2odpA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETR_H_MITH1_1
(EPSILON-THROMBIN)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 HIS A 487
SER A 659
VAL A 677
TRP A 679
GLY A 680
 None
 0.59A 1etrH-2odpA:
23.0		 1etrH-2odpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 7 GLY A 680
ASP A 541
HIS A 487
ALA A 485
 None
 0.98A 1gxsA-2odpA:
2.4
1gxsB-2odpA:
undetectable		 1gxsA-2odpA:
20.35
1gxsB-2odpA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 6 TYR A 389
VAL A 369
ILE A 372
LEU A 235
 None
 0.99A 1j96A-2odpA:
undetectable		 1j96A-2odpA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 7 TYR A 389
VAL A 369
ILE A 372
LEU A 235
 None
 1.04A 1j96B-2odpA:
undetectable		 1j96B-2odpA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 10 GLY A 474
ALA A 475
GLY A 675
ILE A 710
ILE A 477
 None
 0.96A 1muiA-2odpA:
undetectable		 1muiA-2odpA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 7 LEU A 562
LEU A 544
LEU A 676
GLY A 675
 None
 0.83A 1n13D-2odpA:
undetectable
1n13E-2odpA:
undetectable		 1n13D-2odpA:
12.55
1n13E-2odpA:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 GLY A 539
GLY A 523
VAL A 526
GLU A 536
ALA A 486
 None
 1.03A 1nv8B-2odpA:
undetectable		 1nv8B-2odpA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 7 PHE A 672
ALA A 571
ILE A 442
GLU A 268
 None
 1.06A 1oniA-2odpA:
undetectable
1oniB-2odpA:
undetectable		 1oniA-2odpA:
14.54
1oniB-2odpA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 8 ASP A 541
PHE A 524
SER A 659
ALA A 543
 None
 0.96A 1rqpC-2odpA:
undetectable		 1rqpC-2odpA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 8 ASP A 541
PHE A 524
SER A 659
ALA A 543
 None
 0.95A 1rqpA-2odpA:
undetectable		 1rqpA-2odpA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 5 SER A 242
SER A 244
THR A 317
ASN A 360
 MG  A 901 (-1.9A)
MG  A 901 (-2.2A)
MG  A 901 (-2.6A)
None
 0.22A 1yvpA-2odpA:
11.7		 1yvpA-2odpA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 6 SER A 242
SER A 244
THR A 317
ASN A 360
 MG  A 901 (-1.9A)
MG  A 901 (-2.2A)
MG  A 901 (-2.6A)
None
 0.22A 1yvpB-2odpA:
11.7		 1yvpB-2odpA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 9 LEU A 239
LEU A 238
LEU A 354
ILE A 352
ILE A 275
 None
 1.12A 2f7aB-2odpA:
2.0		 2f7aB-2odpA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 7 SER A 242
SER A 244
THR A 317
ASN A 360
 MG  A 901 (-1.9A)
MG  A 901 (-2.2A)
MG  A 901 (-2.6A)
None
 0.24A 2i91A-2odpA:
11.6		 2i91A-2odpA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 7 SER A 242
SER A 244
THR A 317
ASN A 360
 MG  A 901 (-1.9A)
MG  A 901 (-2.2A)
MG  A 901 (-2.6A)
None
 0.24A 2i91B-2odpA:
11.0		 2i91B-2odpA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 GLY A 474
ALA A 475
GLY A 675
ILE A 710
ILE A 477
 None
 0.87A 2nmyA-2odpA:
undetectable		 2nmyA-2odpA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_1
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 TYR A 538
SER A 659
VAL A 677
TRP A 679
GLY A 680
 None
 0.58A 2p16A-2odpA:
23.4		 2p16A-2odpA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 8 ASP A 541
PHE A 524
SER A 659
ALA A 543
 None
 0.96A 2v7uA-2odpA:
undetectable		 2v7uA-2odpA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W26_A_RIVA1001_1
(ACTIVATED FACTOR XA
HEAVY CHAIN)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 TYR A 538
SER A 659
VAL A 677
TRP A 679
GLY A 680
 None
 0.45A 2w26A-2odpA:
23.3		 2w26A-2odpA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 8 LYS A 224
ARG A 558
GLN A 226
GLU A 413
 None
 1.44A 3dh0A-2odpA:
2.4		 3dh0A-2odpA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 GLN A 716
ILE A 710
LEU A 609
VAL A 593
LEU A 665
 None
 1.05A 3gwxB-2odpA:
undetectable		 3gwxB-2odpA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 9 ALA A 257
VAL A 273
ILE A 225
LEU A 233
ILE A 264
 None
 0.99A 3jw3B-2odpA:
undetectable		 3jw3B-2odpA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 HIS A 487
ASP A 541
LYS A 656
GLY A 657
SER A 659
 None
 1.05A 3keeD-2odpA:
9.8		 3keeD-2odpA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 6 VAL A 621
VAL A 639
PHE A 629
GLU A 620
 None
 1.44A 3n61A-2odpA:
undetectable
3n61B-2odpA:
undetectable		 3n61A-2odpA:
20.90
3n61B-2odpA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 ILE A 372
ASN A 234
VAL A 271
ILE A 264
ILE A 351
 None
 1.17A 3ohtA-2odpA:
undetectable
3ohtB-2odpA:
undetectable		 3ohtA-2odpA:
21.00
3ohtB-2odpA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B2000_1
(P38A)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 10 ILE A 264
ILE A 351
ILE A 372
ASN A 234
VAL A 271
 None
 1.21A 3ohtA-2odpA:
undetectable
3ohtB-2odpA:
undetectable		 3ohtA-2odpA:
21.00
3ohtB-2odpA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 6 SER A 659
VAL A 677
TRP A 679
GLY A 680
 None
 0.30A 3rxfA-2odpA:
21.6		 3rxfA-2odpA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 GLY A 474
ALA A 475
GLY A 675
ILE A 710
ILE A 477
 None
 0.92A 3s54A-2odpA:
undetectable		 3s54A-2odpA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 ALA A 475
HIS A 461
MET A 553
LYS A 550
PRO A 559
 None
 1.29A 3tm4A-2odpA:
undetectable		 3tm4A-2odpA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 ALA A 475
HIS A 461
MET A 553
LYS A 550
PRO A 559
 None
 1.26A 3tm4B-2odpA:
undetectable		 3tm4B-2odpA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_A_CLMA221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 9 THR A 317
PHE A 278
SER A 242
LEU A 403
VAL A 398
 MG  A 901 (-2.6A)
None
MG  A 901 (-1.9A)
None
None
 1.36A 3u9fA-2odpA:
0.6		 3u9fA-2odpA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 10 THR A 317
PHE A 278
SER A 242
LEU A 403
VAL A 398
 MG  A 901 (-2.6A)
None
MG  A 901 (-1.9A)
None
None
 1.33A 3u9fK-2odpA:
undetectable		 3u9fK-2odpA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 11 THR A 317
PHE A 278
SER A 242
LEU A 403
VAL A 398
 MG  A 901 (-2.6A)
None
MG  A 901 (-1.9A)
None
None
 1.37A 3u9fN-2odpA:
undetectable
3u9fO-2odpA:
undetectable		 3u9fN-2odpA:
18.11
3u9fO-2odpA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 THR A 317
PHE A 278
SER A 242
LEU A 403
VAL A 398
 MG  A 901 (-2.6A)
None
MG  A 901 (-1.9A)
None
None
 1.32A 3u9fP-2odpA:
undetectable
3u9fS-2odpA:
undetectable		 3u9fP-2odpA:
18.11
3u9fS-2odpA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 8 GLY A 660
GLY A 661
SER A 659
GLY A 657
LEU A 600
 None
 1.37A 3v1nA-2odpA:
undetectable		 3v1nA-2odpA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 LEU A 727
LEU A 676
LEU A 712
ALA A 486
ALA A 485
 None
 1.17A 3vw7A-2odpA:
undetectable		 3vw7A-2odpA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 11 LEU A 303
ILE A 391
ILE A 352
LEU A 235
VAL A 271
 None
 1.14A 3w67A-2odpA:
undetectable		 3w67A-2odpA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		3 / 3 ARG A 382
THR A 341
TRP A 344
 None
 1.20A 4d7hA-2odpA:
undetectable		 4d7hA-2odpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 11 LEU A 235
ILE A 264
ARG A 668
LEU A 354
ILE A 275
 None
 1.13A 4dm8A-2odpA:
undetectable		 4dm8A-2odpA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 6 PHE A 489
ALA A 543
GLY A 474
LEU A 545
VAL A 482
 None
 1.26A 4dubB-2odpA:
undetectable		 4dubB-2odpA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 2odp COMPLEMENT C2
(Homo
sapiens) 		3 / 3 LYS A 366
ASN A 318
ASP A 370
 None
 0.86A 4o1eA-2odpA:
undetectable		 4o1eA-2odpA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 6 LEU A 419
MET A 260
LEU A 354
VAL A 245
 None
 1.17A 4okbA-2odpA:
undetectable		 4okbA-2odpA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		3 / 3 ASP A 356
ASP A 240
ASN A 318
 MG  A 901 ( 4.0A)
MG  A 901 ( 3.9A)
None
 0.72A 4q5mA-2odpA:
undetectable		 4q5mA-2odpA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 MET A 361
THR A 355
VAL A 398
SER A 244
LEU A 406
 None
None
None
MG  A 901 (-2.2A)
None
 1.36A 4qztA-2odpA:
undetectable		 4qztA-2odpA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		3 / 3 ARG A 382
THR A 341
TRP A 344
 None
 1.20A 4ug5A-2odpA:
undetectable		 4ug5A-2odpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		3 / 3 ARG A 382
THR A 341
TRP A 344
 None
 1.22A 4uglA-2odpA:
undetectable		 4uglA-2odpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		3 / 3 ARG A 382
THR A 341
TRP A 344
 None
 1.19A 5g6cA-2odpA:
undetectable		 5g6cA-2odpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2odp COMPLEMENT C2
(Homo
sapiens) 		4 / 6 PHE A 527
VAL A 526
TYR A 538
MET A 628
 None
 1.14A 5iwuA-2odpA:
undetectable		 5iwuA-2odpA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 THR A 640
ALA A 475
SER A 521
ILE A 520
PHE A 524
 None
 1.36A 5iwuA-2odpA:
undetectable		 5iwuA-2odpA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2odp COMPLEMENT C2
(Homo
sapiens) 		3 / 3 SER A 678
SER A 659
PHE A 524
 None
 0.87A 5mugA-2odpA:
2.8		 5mugA-2odpA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 LEU A 719
LEU A 483
SER A 659
LEU A 712
GLY A 539
 None
 0.83A 6b0cD-2odpA:
4.0		 6b0cD-2odpA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 9 ASP A 707
LEU A 600
ALA A 599
VAL A 598
SER A 603
 None
None
NAG  A 807 ( 4.8A)
None
NAG  A 807 (-3.4A)
 1.38A 6c2mB-2odpA:
9.4		 6c2mB-2odpA:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 2odp COMPLEMENT C2
(Homo
sapiens) 		5 / 12 SER A 256
LEU A 406
PHE A 278
ASP A 240
ILE A 252
 None
None
None
MG  A 901 ( 3.9A)
None
 1.49A 6dwnB-2odpA:
undetectable		 6dwnB-2odpA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 2odp COMPLEMENT C2
(Homo
sapiens) 		3 / 3 PHE A 713
ARG A 714
GLN A 716
 None
 1.18A 6g1pB-2odpA:
undetectable		 6g1pB-2odpA:
22.27