SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2odr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		5 / 10 GLY B 321
VAL B 322
ILE B 211
TYR B  59
GLY B 319
 None
 1.13A 1fohA-2odrB:
undetectable		 1fohA-2odrB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		5 / 10 GLY B 321
VAL B 322
ILE B 211
TYR B  59
GLY B 319
 None
 1.12A 1fohB-2odrB:
undetectable		 1fohB-2odrB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		5 / 10 GLY B 321
VAL B 322
ILE B 211
TYR B  59
GLY B 319
 None
 1.10A 1fohC-2odrB:
undetectable		 1fohC-2odrB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_D_IPHD802_0
(PHENOL HYDROXYLASE)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		5 / 10 GLY B 321
VAL B 322
ILE B 211
TYR B  59
GLY B 319
 None
 1.09A 1fohD-2odrB:
undetectable		 1fohD-2odrB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		4 / 6 PHE B 298
PHE B 264
LEU B 254
VAL B 295
 None
 1.01A 1hk1A-2odrB:
undetectable		 1hk1A-2odrB:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		4 / 7 PHE B 298
PHE B 264
LEU B 254
VAL B 295
 None
 1.01A 1hk3A-2odrB:
undetectable		 1hk3A-2odrB:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		5 / 10 GLY B 321
VAL B 322
ILE B 211
TYR B  59
GLY B 319
 None
 1.13A 1pn0A-2odrB:
undetectable		 1pn0A-2odrB:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		5 / 10 GLY B 321
VAL B 322
ILE B 211
TYR B  59
GLY B 319
 None
 1.13A 1pn0B-2odrB:
undetectable		 1pn0B-2odrB:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		5 / 10 GLY B 321
VAL B 322
ILE B 211
TYR B  59
GLY B 319
 None
 1.09A 1pn0C-2odrB:
undetectable		 1pn0C-2odrB:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		5 / 10 GLY B 321
VAL B 322
ILE B 211
TYR B  59
GLY B 319
 None
 1.09A 1pn0D-2odrB:
undetectable		 1pn0D-2odrB:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		3 / 3 ARG B  76
SER B 302
TYR B 273
 None
 0.76A 1x70A-2odrB:
undetectable		 1x70A-2odrB:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		4 / 7 GLY B 190
GLN B  81
PHE B  82
ILE B  78
 None
 0.96A 2qmzA-2odrB:
undetectable
2qmzB-2odrB:
undetectable		 2qmzA-2odrB:
15.25
2qmzB-2odrB:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		5 / 9 PHE B  64
PHE B 298
ALA B 248
VAL B 241
VAL B 300
 None
 1.22A 3me6C-2odrB:
undetectable		 3me6C-2odrB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		5 / 9 PHE B  64
PHE B 298
ALA B 248
VAL B 241
VAL B 300
 None
 1.21A 3me6D-2odrB:
undetectable		 3me6D-2odrB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_DIFB585_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		5 / 12 VAL B 295
SER B 231
ILE B 211
LEU B 253
LEU B 254
 None
 1.02A 3n8yB-2odrB:
undetectable		 3n8yB-2odrB:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		4 / 8 GLY B 190
GLN B  81
PHE B  82
ILE B  78
 None
 0.82A 4fglD-2odrB:
undetectable		 4fglD-2odrB:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		4 / 7 GLY B 190
GLN B  81
PHE B  82
ILE B  78
 None
 0.81A 4fglC-2odrB:
undetectable		 4fglC-2odrB:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		3 / 3 MET B 316
GLN B  81
TYR B 309
 None
 1.07A 4udcA-2odrB:
undetectable		 4udcA-2odrB:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUQ_A_ACTA1278_0
(NAD(P)H
DEHYDROGENASE
[QUINONE] 1)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		4 / 5 HIS B 186
SER B 185
GLN B  81
ILE B  78
 None
 1.38A 5fuqA-2odrB:
0.0
5fuqB-2odrB:
0.0		 5fuqA-2odrB:
19.63
5fuqB-2odrB:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		3 / 3 PHE B 192
ASP B  77
LYS B  80
 None
 0.79A 6awtD-2odrB:
undetectable		 6awtD-2odrB:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 2odr PHOSPHOSERYL-TRNA
SYNTHETASE
(Methanococcus
maripaludis) 		4 / 6 ARG B  37
SER B  34
THR B 372
ALA B 470
 None
 1.13A 6ma6A-2odrB:
undetectable		 6ma6A-2odrB:
7.72