SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2odt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		4 / 6 GLU X 146
LEU X 145
VAL X 187
MET X 131
 None
 1.08A 1hk1A-2odtX:
undetectable		 1hk1A-2odtX:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		4 / 6 GLY X  51
ILE X  47
GLN X  50
VAL X  39
 None
 1.01A 1rs7B-2odtX:
undetectable		 1rs7B-2odtX:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		5 / 9 LEU X 244
LEU X 215
PHE X 230
ARG X 225
ILE X 228
 None
 1.15A 2f78B-2odtX:
undetectable		 2f78B-2odtX:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		5 / 9 LEU X 244
LEU X 215
PHE X 230
ARG X 225
ILE X 228
 None
 1.08A 2f7aA-2odtX:
undetectable		 2f7aA-2odtX:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R6V_A_NCAA174_0
(UNCHARACTERIZED
PROTEIN PH0856)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		4 / 6 TYR X 207
ASP X 259
ARG X 124
HIS X 291
 None
 1.39A 2r6vA-2odtX:
0.0		 2r6vA-2odtX:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		4 / 7 ARG X  32
PHE X  27
PHE X  24
ILE X 316
 None
 1.13A 2zseA-2odtX:
undetectable		 2zseA-2odtX:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		4 / 8 LEU X  43
SER X  44
LEU X  97
ILE X  47
 None
 0.93A 3ln1A-2odtX:
undetectable		 3ln1A-2odtX:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		4 / 7 LEU X  43
SER X  44
LEU X  97
ILE X  47
 None
 0.92A 3ln1B-2odtX:
undetectable		 3ln1B-2odtX:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		3 / 3 PHE X 299
TYR X  12
LEU X 104
 None
 0.74A 3sueB-2odtX:
undetectable		 3sueB-2odtX:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOD_A_HQEA1173_1
(FMN-BINDING PROTEIN)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		4 / 7 TYR X 207
ASP X 259
ARG X 124
HIS X 291
 None
 1.38A 3zodA-2odtX:
undetectable		 3zodA-2odtX:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		4 / 6 GLY X  51
ILE X  47
GLN X  50
VAL X  39
 None
 1.10A 4d39B-2odtX:
undetectable		 4d39B-2odtX:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		4 / 5 VAL X  10
ARG X   9
MET X  36
GLU X  37
 None
 1.43A 4hojA-2odtX:
undetectable		 4hojA-2odtX:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		3 / 3 SER X 214
ASP X 259
ASP X 281
 None
 0.73A 4uckA-2odtX:
undetectable		 4uckA-2odtX:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		3 / 3 ASP X 295
SER X 109
TYR X 110
 None
 0.79A 5glmA-2odtX:
undetectable		 5glmA-2odtX:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		4 / 8 ILE X 280
GLY X 279
PHE X 230
PHE X 190
 None
 0.85A 5hieD-2odtX:
undetectable		 5hieD-2odtX:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		3 / 3 ASP X 281
PHE X 201
ARG X 212
 None
 1.03A 5yw0A-2odtX:
undetectable		 5yw0A-2odtX:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		5 / 12 ILE X 113
LEU X 103
LEU X 269
ALA X 272
LEU X 273
 None
 1.18A 6ajiA-2odtX:
undetectable		 6ajiA-2odtX:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE
(Homo
sapiens) 		3 / 3 ASP X 295
SER X 214
SER X 236
 None
 0.84A 6mxtA-2odtX:
undetectable		 6mxtA-2odtX:
20.97