SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oe1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FHZ_D_READ602_1 (ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3)	2oe1	THIOREDOXIN-3 (Saccharomyces cerevisiae)	5 / 12	ILE A 65 GLU A 68 ARG A 14 THR A 5 LEU A 16	None SO4 A1002 (-4.3A) SO4 A1003 ( 4.4A) None None	1.28A	5fhzD-2oe1A: undetectable	5fhzD-2oe1A: 14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HIE_A_P06A801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	2oe1	THIOREDOXIN-3 (Saccharomyces cerevisiae)	4 / 7	ILE A 90 GLY A 91 CYH A 69 ASP A 26	None None SO4 A1002 ( 4.8A) None	0.92A	5hieA-2oe1A: undetectable	5hieA-2oe1A: 20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HIE_D_P06D801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	2oe1	THIOREDOXIN-3 (Saccharomyces cerevisiae)	4 / 8	ILE A 90 GLY A 91 CYH A 69 ASP A 26	None None SO4 A1002 ( 4.8A) None	0.94A	5hieD-2oe1A: undetectable	5hieD-2oe1A: 20.14