SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oej'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_2
(PROTEIN (HIV-1
PROTEASE))		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		5 / 8 LEU A 298
ALA A 294
GLY A 126
ILE A 130
VAL A 297
 None
 1.12A 1d4sB-2oejA:
undetectable		 1d4sB-2oejA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_2
(PROTEIN (HIV-1
PROTEASE))		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		4 / 8 LEU A 298
ALA A 294
GLY A 126
ILE A 130
 None
 0.69A 1d4yB-2oejA:
undetectable		 1d4yB-2oejA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		3 / 3 VAL A 266
VAL A 240
ASP A 180
 None
 0.70A 2fumD-2oejA:
undetectable		 2fumD-2oejA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_1
(PROTEASE)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		5 / 11 GLY A 232
ALA A 233
ASP A 234
GLY A 193
PRO A 185
 None
 0.96A 2nnpA-2oejA:
undetectable		 2nnpA-2oejA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		5 / 12 GLY A 232
ALA A 233
ASP A 234
GLY A 193
PRO A 185
 None
 0.87A 3ndtA-2oejA:
undetectable		 3ndtA-2oejA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		4 / 5 ASN A 357
ASP A 175
THR A 215
SER A 335
 None
 1.20A 3p2kC-2oejA:
undetectable		 3p2kC-2oejA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		4 / 8 GLY A 232
ALA A 233
ASP A 234
GLY A 193
 None
 0.70A 3so9A-2oejA:
undetectable		 3so9A-2oejA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		4 / 7 LEU A 298
ALA A 294
GLY A 126
ILE A 130
 None
 0.62A 3spkB-2oejA:
undetectable		 3spkB-2oejA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		3 / 3 PRO A 185
ASP A 180
GLU A 187
 None
 0.83A 3v4tC-2oejA:
0.5		 3v4tC-2oejA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		3 / 3 ASN A 239
LEU A 289
PHE A 267
 None
 0.80A 4dajB-2oejA:
undetectable		 4dajB-2oejA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		5 / 10 LEU A 298
ALA A 294
GLY A 126
ILE A 130
VAL A 333
 None
 0.86A 4dqbB-2oejA:
undetectable		 4dqbB-2oejA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		5 / 10 LEU A 298
ALA A 294
GLY A 126
ILE A 130
VAL A 333
 None
 0.83A 4dqeB-2oejA:
undetectable		 4dqeB-2oejA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		5 / 10 LEU A 298
ALA A 294
GLY A 126
ILE A 130
VAL A 333
 None
 0.88A 4dqhB-2oejA:
undetectable		 4dqhB-2oejA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		5 / 12 GLY A 286
SER A 282
ASP A 322
ALA A 330
PHE A 327
 None
 1.19A 4dx5B-2oejA:
4.1		 4dx5B-2oejA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		4 / 6 ARG A 189
GLY A 193
ALA A 228
GLN A 164
 None
 1.01A 4g0uA-2oejA:
undetectable		 4g0uA-2oejA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		5 / 11 LEU A 298
ALA A 294
GLY A 126
ILE A 130
VAL A 333
 None
 0.87A 4hlaB-2oejA:
undetectable		 4hlaB-2oejA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		4 / 4 TYR A  79
THR A   7
VAL A  51
ILE A  23
 None
 1.27A 4jx1F-2oejA:
undetectable		 4jx1F-2oejA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		5 / 12 GLY A 368
ALA A 369
GLY A 372
PHE A 376
GLY A 364
 None
 0.80A 4o33A-2oejA:
undetectable		 4o33A-2oejA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		4 / 4 ALA A 375
ALA A 378
ALA A 379
ALA A 382
 None
 0.12A 4oadA-2oejA:
undetectable		 4oadA-2oejA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		4 / 4 ALA A 375
ALA A 378
ALA A 379
ALA A 382
 None
 0.12A 4oaeA-2oejA:
1.7		 4oaeA-2oejA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		5 / 12 GLY A 286
SER A 282
ASP A 322
ALA A 330
PHE A 327
 None
 1.13A 4u8vB-2oejA:
3.3		 4u8vB-2oejA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		5 / 8 ALA A 258
ILE A 257
ALA A 263
PHE A 238
LEU A 214
 None
 1.24A 4v1fA-2oejA:
undetectable
4v1fB-2oejA:
undetectable		 4v1fA-2oejA:
13.50
4v1fB-2oejA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		4 / 5 GLY A 103
TYR A   8
GLU A 104
ASP A 102
 None
 1.05A 4xueA-2oejA:
undetectable		 4xueA-2oejA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		4 / 6 LEU A  99
ILE A  23
ALA A  24
THR A  28
 None
 0.59A 4zf8A-2oejA:
undetectable		 4zf8A-2oejA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		4 / 5 ILE A  77
ILE A  53
ARG A  17
GLU A  21
 None
 1.27A 4zzcE-2oejA:
undetectable		 4zzcE-2oejA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		3 / 3 ILE A 403
VAL A 408
PRO A 344
 None
 0.71A 5uunA-2oejA:
undetectable		 5uunA-2oejA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		4 / 8 GLY A 341
ILE A 403
HIS A 365
PRO A 366
 None
 0.90A 6ag0A-2oejA:
10.0		 6ag0A-2oejA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		5 / 12 PHE A 331
LEU A 320
ASP A 128
GLY A 126
LEU A 141
 None
 1.06A 6dwnC-2oejA:
undetectable		 6dwnC-2oejA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6PAH_A_DAHA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE
(Geobacillus
kaustophilus) 		4 / 6 LEU A 178
HIS A 363
TYR A 156
GLU A 160
 None
 1.05A 6pahA-2oejA:
undetectable		 6pahA-2oejA:
20.14