SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2of7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 2of7 PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR
(Streptomyces
coelicolor) 		4 / 8 TYR A  78
LEU A 120
LEU A  74
GLU A 127
 None
 1.11A 1i7zA-2of7A:
undetectable		 1i7zA-2of7A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 2of7 PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR
(Streptomyces
coelicolor) 		4 / 7 VAL A  62
ILE A  51
ALA A  55
VAL A  57
 None
 0.43A 2xrzB-2of7A:
undetectable		 2xrzB-2of7A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 2of7 PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR
(Streptomyces
coelicolor) 		5 / 11 ARG A  54
TYR A  43
VAL A 128
PRO A 129
ILE A  72
 None
 1.47A 3ganA-2of7A:
0.0		 3ganA-2of7A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 2of7 PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR
(Streptomyces
coelicolor) 		3 / 3 VAL A  57
SER A  58
THR A  61
 None
 0.42A 4luhA-2of7A:
2.9		 4luhA-2of7A:
16.87