SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ofq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DF7_A_MTXA501_2 (DIHYDROFOLATE REDUCTASE)	2ofq	TRAO (IncN plasmid R46)	3 / 3	TRP A 201 ARG A 265 THR A 207	None	0.92A	1df7A-2ofqA: undetectable	1df7A-2ofqA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RXC_C_URFC2081_1 (URIDINE PHOSPHORYLASE)	2ofq	TRAO (IncN plasmid R46)	4 / 7	GLY A 263 ILE A 255 VAL A 262 PRO A 197	None	1.06A	1rxcC-2ofqA: undetectable	1rxcC-2ofqA: 14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CP4_A_CAMA416_0 (CYTOCHROME P450-CAM)	2ofq	TRAO TRAN (IncN plasmid R46; IncN plasmid R46)	5 / 10	PHE A 211 VAL A 262 GLY A 263 VAL A 200 VAL B 33	None	1.32A	2cp4A-2ofqA: undetectable	2cp4A-2ofqA: 13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_C_SVRC505_2 (PHOSPHOLIPASE A2)	2ofq	TRAO (IncN plasmid R46)	4 / 5	VAL A 237 VAL A 236 GLN A 219 PHE A 206	None	1.32A	3bjwH-2ofqA: undetectable	3bjwH-2ofqA: 24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_C_SVRC507_2 (PHOSPHOLIPASE A2)	2ofq	TRAO (IncN plasmid R46)	4 / 6	VAL A 237 VAL A 236 GLN A 219 PHE A 206	None	1.23A	3bjwF-2ofqA: undetectable	3bjwF-2ofqA: 24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CP4_A_CAMA422_0 (CYTOCHROME P450CAM)	2ofq	TRAO TRAN (IncN plasmid R46; IncN plasmid R46)	5 / 9	PHE A 211 VAL A 262 GLY A 263 VAL A 200 VAL B 33	None	1.25A	5cp4A-2ofqA: undetectable	5cp4A-2ofqA: 13.72

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DF7_A_MTXA501_2","DIHYDROFOLATE REDUCTASE","2ofq","TRAO","IncN plasmid R46",3,"TRP A 201;ARG A 265;THR A 207","None","0.92A","1df7A-2ofqA:undetectable","1df7A-2ofqA:21.15"],["1RXC_C_URFC2081_1","URIDINE PHOSPHORYLASE","2ofq","TRAO","IncN plasmid R46",4,"GLY A 263;ILE A 255;VAL A 262;PRO A 197","None","1.06A","1rxcC-2ofqA:undetectable","1rxcC-2ofqA:14.62"],["2CP4_A_CAMA416_0","CYTOCHROME P450-CAM","2ofq","TRAO;TRAN","IncN plasmid R46;IncN plasmid R46",5,"PHE A 211;VAL A 262;GLY A 263;VAL A 200;VAL B  33","None","1.32A","2cp4A-2ofqA:undetectable","2cp4A-2ofqA:13.72"],["3BJW_C_SVRC505_2","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","2ofq","TRAO","IncN plasmid R46",4,"VAL A 237;VAL A 236;GLN A 219;PHE A 206","None","1.32A","3bjwH-2ofqA:undetectable","3bjwH-2ofqA:24.37"],["3BJW_C_SVRC507_2","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","2ofq","TRAO","IncN plasmid R46",4,"VAL A 237;VAL A 236;GLN A 219;PHE A 206","None","1.23A","3bjwF-2ofqA:undetectable","3bjwF-2ofqA:24.37"],["5CP4_A_CAMA422_0","CYTOCHROME P450CAM","2ofq","TRAO;TRAN","IncN plasmid R46;IncN plasmid R46",5,"PHE A 211;VAL A 262;GLY A 263;VAL A 200;VAL B  33","None","1.25A","5cp4A-2ofqA:undetectable","5cp4A-2ofqA:13.72"]]