SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2og2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 4 THR A  36
LEU A  40
VAL A  42
LEU A  46
 None
 0.66A 1fbmD-2og2A:
undetectable		 1fbmD-2og2A:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 5 THR A  36
LEU A  40
VAL A  42
LEU A  46
 None
 0.68A 1fbmE-2og2A:
undetectable		 1fbmE-2og2A:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 5 PHE A 322
GLY A 288
SER A 293
PHE A  71
 None
 1.04A 1icvA-2og2A:
undetectable
1icvB-2og2A:
undetectable		 1icvA-2og2A:
20.41
1icvB-2og2A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		5 / 12 GLY A 306
LEU A 253
MET A 261
THR A  36
ILE A 326
 None
 1.14A 1p93B-2og2A:
undetectable		 1p93B-2og2A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 6 GLU A 174
ALA A 160
LEU A 214
VAL A 197
 None
 1.14A 1sn5A-2og2A:
undetectable		 1sn5A-2og2A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 6 ILE A 278
VAL A 197
ILE A 184
ASP A 163
 None
 0.78A 1uwhA-2og2A:
undetectable		 1uwhA-2og2A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 6 ILE A 278
VAL A 197
ILE A 184
ASP A 163
 None
 0.78A 1uwhB-2og2A:
undetectable		 1uwhB-2og2A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 4 LEU A 150
PRO A 246
ILE A 131
LEU A 214
 None
 1.17A 1ya4C-2og2A:
2.1		 1ya4C-2og2A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 THR A 217
LEU A 198
VAL A 238
VAL A 272
 None
 1.05A 1yrcA-2og2A:
undetectable		 1yrcA-2og2A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 6 THR A 217
LEU A 198
VAL A 238
VAL A 272
 None
 1.07A 2feuA-2og2A:
undetectable		 2feuA-2og2A:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 ILE A  79
SER A 105
PHE A 327
ILE A 326
 None
 1.01A 2qb4A-2og2A:
undetectable		 2qb4A-2og2A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		3 / 3 LEU A 262
PRO A 263
ARG A 287
 None
 0.49A 2qd4B-2og2A:
4.0		 2qd4B-2og2A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		3 / 3 LEU A 262
PRO A 263
ARG A 287
 None
 0.62A 2qd5A-2og2A:
3.1		 2qd5A-2og2A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 8 LEU A  59
LEU A  92
LYS A  93
LEU A  47
 None
 0.82A 2xn3A-2og2A:
undetectable
2xn3B-2og2A:
undetectable		 2xn3A-2og2A:
23.18
2xn3B-2og2A:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 8 THR A 196
VAL A 197
LEU A 198
ALA A 237
 None
 1.02A 3ax7A-2og2A:
undetectable		 3ax7A-2og2A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 THR A 217
LEU A 198
VAL A 238
VAL A 272
 None
 1.04A 3fwfA-2og2A:
undetectable		 3fwfA-2og2A:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 THR A 217
LEU A 198
VAL A 238
VAL A 272
 None
 1.04A 3fwfB-2og2A:
undetectable		 3fwfB-2og2A:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		5 / 12 GLY A 306
GLY A  32
ILE A 278
ASP A 313
LEU A 314
 None
 0.97A 3ihtA-2og2A:
2.9		 3ihtA-2og2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN201_1
(PROTEIN S100-A4)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		5 / 10 GLY A 244
GLY A 122
CYH A 215
ILE A 129
MET A 130
 None
 1.30A 3ko0L-2og2A:
2.9
3ko0N-2og2A:
2.9		 3ko0L-2og2A:
16.61
3ko0N-2og2A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		5 / 10 GLY A 122
CYH A 215
ILE A 129
MET A 130
GLY A 244
 None
 1.33A 3ko0R-2og2A:
3.0
3ko0T-2og2A:
3.4		 3ko0R-2og2A:
16.61
3ko0T-2og2A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 THR A 217
LEU A 198
VAL A 238
VAL A 272
 None
 1.03A 3l63A-2og2A:
undetectable		 3l63A-2og2A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		5 / 9 VAL A 238
LEU A 250
ILE A 129
GLU A 248
THR A 275
 None
 1.10A 3mdvA-2og2A:
undetectable		 3mdvA-2og2A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 THR A 217
LEU A 198
VAL A 238
VAL A 272
 None
 1.04A 3wrhA-2og2A:
undetectable		 3wrhA-2og2A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 THR A 217
LEU A 198
VAL A 238
VAL A 272
 None
 1.03A 3wrlA-2og2A:
undetectable		 3wrlA-2og2A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 THR A 217
LEU A 198
VAL A 238
VAL A 272
 None
 1.03A 3wrlE-2og2A:
undetectable		 3wrlE-2og2A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		5 / 11 LEU A 198
CYH A 215
PRO A 246
VAL A 128
VAL A 272
 None
 1.35A 4mk4B-2og2A:
3.6		 4mk4B-2og2A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 5 PHE A 304
HIS A 148
LEU A 150
PRO A 316
 None
 1.28A 5csyB-2og2A:
2.2		 5csyB-2og2A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		5 / 8 LEU A 110
ILE A  75
PHE A 322
GLY A 289
LEU A 279
 None
 1.46A 5eseA-2og2A:
undetectable		 5eseA-2og2A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		3 / 3 CYH A 290
MET A 261
ASN A 260
 None
 0.94A 5qh8A-2og2A:
undetectable		 5qh8A-2og2A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 ILE A  79
LEU A 110
PHE A 322
ARG A  37
 None
 0.99A 5vc0A-2og2A:
undetectable		 5vc0A-2og2A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 THR A 217
LEU A 198
VAL A 238
VAL A 272
 None
 1.04A 5wk9A-2og2A:
undetectable		 5wk9A-2og2A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		3 / 3 LEU A 221
THR A 257
ASN A 260
 None
 0.64A 6baaE-2og2A:
3.4		 6baaE-2og2A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		3 / 3 LEU A 221
THR A 257
ASN A 260
 None
 0.64A 6baaF-2og2A:
3.5		 6baaF-2og2A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		3 / 3 LEU A 221
THR A 257
ASN A 260
 None
 0.65A 6baaG-2og2A:
2.6		 6baaG-2og2A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		3 / 3 LEU A 221
THR A 257
ASN A 260
 None
 0.65A 6baaH-2og2A:
3.3		 6baaH-2og2A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR
(Arabidopsis
thaliana) 		5 / 12 GLY A 288
ASP A  70
VAL A 294
GLY A 255
VAL A 302
 None
 0.97A 6dj2B-2og2A:
undetectable		 6dj2B-2og2A:
16.01