SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ogf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 2ogf HYPOTHETICAL PROTEIN
MJ0408
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A  45
PRO A  41
LEU A  81
ARG A  52
 None
 1.35A 1i2wA-2ogfA:
undetectable		 1i2wA-2ogfA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		 2ogf HYPOTHETICAL PROTEIN
MJ0408
(Methanocaldococc
us
jannaschii) 		4 / 6 TYR A 115
LEU A  30
LYS A  91
ASP A  66
 None
 1.24A 2w98A-2ogfA:
undetectable
2w98B-2ogfA:
undetectable		 2w98A-2ogfA:
16.45
2w98B-2ogfA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 2ogf HYPOTHETICAL PROTEIN
MJ0408
(Methanocaldococc
us
jannaschii) 		4 / 6 LEU A  33
THR A  29
LEU A 101
ASP A  87
 None
 1.08A 2wm3A-2ogfA:
undetectable		 2wm3A-2ogfA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)		 2ogf HYPOTHETICAL PROTEIN
MJ0408
(Methanocaldococc
us
jannaschii) 		4 / 7 ARG A   2
ALA A  22
GLY A  27
ILE A  28
 None
None
None
OXG  A 602 (-3.7A)
 0.82A 3spkB-2ogfA:
undetectable		 3spkB-2ogfA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2ogf HYPOTHETICAL PROTEIN
MJ0408
(Methanocaldococc
us
jannaschii) 		4 / 7 ILE A  92
LEU A 101
GLY A  27
GLY A  26
 None
 0.82A 5a06A-2ogfA:
undetectable		 5a06A-2ogfA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2ogf HYPOTHETICAL PROTEIN
MJ0408
(Methanocaldococc
us
jannaschii) 		4 / 7 ILE A  92
LEU A 101
GLY A  27
GLY A  26
 None
 0.85A 5a06B-2ogfA:
2.3		 5a06B-2ogfA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2ogf HYPOTHETICAL PROTEIN
MJ0408
(Methanocaldococc
us
jannaschii) 		4 / 7 ILE A  92
LEU A 101
GLY A  27
GLY A  26
 None
 0.84A 5a06C-2ogfA:
undetectable		 5a06C-2ogfA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2ogf HYPOTHETICAL PROTEIN
MJ0408
(Methanocaldococc
us
jannaschii) 		4 / 7 ILE A  92
LEU A 101
GLY A  27
GLY A  26
 None
 0.83A 5a06E-2ogfA:
undetectable		 5a06E-2ogfA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2ogf HYPOTHETICAL PROTEIN
MJ0408
(Methanocaldococc
us
jannaschii) 		4 / 7 ILE A  92
LEU A 101
GLY A  27
GLY A  26
 None
 0.81A 5a06F-2ogfA:
2.1		 5a06F-2ogfA:
16.17