SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ogg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1O86_A_LPRA702_1 (ANGIOTENSIN CONVERTING ENZYME)	2ogg	TREHALOSE OPERON TRANSCRIPTIONAL REPRESSOR (Bacillus subtilis)	5 / 12	GLU A 183 GLN A 114 GLU A 188 GLU A 125 TYR A 143	None None None GOL A 304 (-4.4A) None	1.37A	1o86A-2oggA: undetectable	1o86A-2oggA: 12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZZ1_A_SHHA2452_1 (HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE)	2ogg	TREHALOSE OPERON TRANSCRIPTIONAL REPRESSOR (Bacillus subtilis)	5 / 11	LEU A 115 ILE A 123 HIS A 148 ASP A 212 PHE A 216	None GOL A 304 (-4.5A) None None None	1.25A	1zz1A-2oggA: undetectable	1zz1A-2oggA: 17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7T_A_5FWA1001_1 (SUPEROXIDE DISMUTASE [CU-ZN])	2ogg	TREHALOSE OPERON TRANSCRIPTIONAL REPRESSOR (Bacillus subtilis)	3 / 3	ASP A 140 LYS A 141 ASP A 142	None None SO4 A 302 ( 4.8A)	0.84A	4a7tA-2oggA: undetectable	4a7tA-2oggA: 24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCG_A_08YA602_2 (CYTOCHROME P450 3A4)	2ogg	TREHALOSE OPERON TRANSCRIPTIONAL REPRESSOR (Bacillus subtilis)	3 / 3	ARG A 222 ARG A 190 ARG A 224	None	1.00A	5vcgA-2oggA: undetectable	5vcgA-2oggA: 19.28

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1O86_A_LPRA702_1","ANGIOTENSIN CONVERTING ENZYME","2ogg","TREHALOSE OPERON TRANSCRIPTIONAL REPRESSOR","Bacillus subtilis",5,"GLU A 183;GLN A 114;GLU A 188;GLU A 125;TYR A 143","None;None;None;GOL A 304 (-4.4A);None","1.37A","1o86A-2oggA:undetectable","1o86A-2oggA:12.13"],["1ZZ1_A_SHHA2452_1","HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE","2ogg","TREHALOSE OPERON TRANSCRIPTIONAL REPRESSOR","Bacillus subtilis",5,"LEU A 115;ILE A 123;HIS A 148;ASP A 212;PHE A 216","None;GOL A 304 (-4.5A);None;None;None","1.25A","1zz1A-2oggA:undetectable","1zz1A-2oggA:17.16"],["4A7T_A_5FWA1001_1","SUPEROXIDE DISMUTASE [CU-ZN]","2ogg","TREHALOSE OPERON TRANSCRIPTIONAL REPRESSOR","Bacillus subtilis",3,"ASP A 140;LYS A 141;ASP A 142","None;None;SO4 A 302 ( 4.8A)","0.84A","4a7tA-2oggA:undetectable","4a7tA-2oggA:24.84"],["5VCG_A_08YA602_2","CYTOCHROME P450 3A4","2ogg","TREHALOSE OPERON TRANSCRIPTIONAL REPRESSOR","Bacillus subtilis",3,"ARG A 222;ARG A 190;ARG A 224","None","1.00A","5vcgA-2oggA:undetectable","5vcgA-2oggA:19.28"]]