SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ogi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		4 / 5 HIS A  58
HIS A  91
HIS A 117
ASP A 135
 FE  A 301 (-3.5A)
FE  A 302 ( 3.4A)
FE  A 302 ( 3.3A)
FE  A 301 ( 2.5A)
 0.95A 1e9yB-2ogiA:
undetectable		 1e9yB-2ogiA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		4 / 8 ASP A  59
HIS A  58
HIS A 117
HIS A  29
 FE  A 302 (-2.5A)
FE  A 301 (-3.5A)
FE  A 302 ( 3.3A)
FE  A 301 ( 3.4A)
 0.69A 1ei6D-2ogiA:
undetectable		 1ei6D-2ogiA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		5 / 12 LEU A  14
GLU A  34
GLY A  52
ALA A  54
ALA A 113
 None
 1.02A 2br4B-2ogiA:
undetectable		 2br4B-2ogiA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		4 / 8 HIS A 117
ASP A 135
HIS A  91
ASP A  59
 FE  A 302 ( 3.3A)
FE  A 301 ( 2.5A)
FE  A 302 ( 3.4A)
FE  A 302 (-2.5A)
 1.02A 2xadA-2ogiA:
undetectable		 2xadA-2ogiA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		4 / 8 HIS A 117
ASP A 135
HIS A  91
ASP A  59
 FE  A 302 ( 3.3A)
FE  A 301 ( 2.5A)
FE  A 302 ( 3.4A)
FE  A 302 (-2.5A)
 1.04A 2xadB-2ogiA:
undetectable		 2xadB-2ogiA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		4 / 8 HIS A 117
ASP A 135
HIS A  91
ASP A  59
 FE  A 302 ( 3.3A)
FE  A 301 ( 2.5A)
FE  A 302 ( 3.4A)
FE  A 302 (-2.5A)
 1.03A 2xadC-2ogiA:
undetectable		 2xadC-2ogiA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		4 / 8 HIS A 117
ASP A 135
HIS A  91
ASP A  59
 FE  A 302 ( 3.3A)
FE  A 301 ( 2.5A)
FE  A 302 ( 3.4A)
FE  A 302 (-2.5A)
 1.04A 2xadD-2ogiA:
undetectable		 2xadD-2ogiA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		4 / 5 PRO A  78
ILE A  73
TYR A  97
TYR A  76
 None
 1.40A 3d9lA-2ogiA:
undetectable
3d9lY-2ogiA:
undetectable		 3d9lA-2ogiA:
17.91
3d9lY-2ogiA:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		5 / 7 LEU A 157
ALA A 134
GLY A  52
ILE A  38
THR A 126
 None
None
None
CL  A 304 ( 4.6A)
None
 1.47A 3spkB-2ogiA:
undetectable		 3spkB-2ogiA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		5 / 12 VAL A  33
LEU A 127
GLU A 164
ILE A 137
ALA A 160
 None
 1.09A 4ltwA-2ogiA:
undetectable		 4ltwA-2ogiA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		5 / 12 GLU A  39
ALA A  55
GLY A  52
LEU A  56
TYR A   3
 None
 0.92A 4oadA-2ogiA:
undetectable		 4oadA-2ogiA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		5 / 6 HIS A  58
HIS A  29
HIS A  91
HIS A 117
ASP A 135
 FE  A 301 (-3.5A)
FE  A 301 ( 3.4A)
FE  A 302 ( 3.4A)
FE  A 302 ( 3.3A)
FE  A 301 ( 2.5A)
 0.99A 4ubpC-2ogiA:
undetectable		 4ubpC-2ogiA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		3 / 3 TYR A  76
ARG A  71
LYS A  75
 None
 1.20A 4wq5B-2ogiA:
undetectable		 4wq5B-2ogiA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		4 / 6 ASP A  59
HIS A 117
HIS A  91
HIS A  29
 FE  A 302 (-2.5A)
FE  A 302 ( 3.3A)
FE  A 302 ( 3.4A)
FE  A 301 ( 3.4A)
 0.93A 5ncdA-2ogiA:
undetectable
5ncdD-2ogiA:
undetectable		 5ncdA-2ogiA:
24.32
5ncdD-2ogiA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		5 / 12 VAL A 131
ASP A 135
LEU A  14
LEU A  53
ALA A  54
 None
FE  A 301 ( 2.5A)
None
None
None
 1.26A 5nd3B-2ogiA:
undetectable		 5nd3B-2ogiA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		4 / 8 ASP A  59
HIS A 117
HIS A  91
HIS A  29
 FE  A 302 (-2.5A)
FE  A 302 ( 3.3A)
FE  A 302 ( 3.4A)
FE  A 301 ( 3.4A)
 0.99A 5nekB-2ogiA:
undetectable		 5nekB-2ogiA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2ogi HYPOTHETICAL PROTEIN
SAG1661
(Streptococcus
agalactiae) 		4 / 6 ASP A  59
HIS A 117
HIS A  91
HIS A  29
 FE  A 302 (-2.5A)
FE  A 302 ( 3.3A)
FE  A 302 ( 3.4A)
FE  A 301 ( 3.4A)
 0.91A 5nelA-2ogiA:
undetectable
5nelD-2ogiA:
undetectable		 5nelA-2ogiA:
24.32
5nelD-2ogiA:
24.32