SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ogj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		3 / 3 VAL A 325
VAL A 321
TRP A  73
 None
 0.98A 1av2A-2ogjA:
undetectable
1av2B-2ogjA:
undetectable		 1av2A-2ogjA:
3.38
1av2B-2ogjA:
3.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		4 / 5 HIS A  77
HIS A 208
HIS A 231
ASP A 291
 KCX  A 175 (-3.3A)
ZN  A 419 (-3.4A)
ZN  A 419 (-3.6A)
ZN  A 418 (-2.5A)
 0.85A 1e9yB-2ogjA:
18.4		 1e9yB-2ogjA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 6 HIS A  77
HIS A  79
HIS A 208
HIS A 231
ASP A 291
 KCX  A 175 (-3.3A)
ZN  A 418 (-3.4A)
ZN  A 419 (-3.4A)
ZN  A 419 (-3.6A)
ZN  A 418 (-2.5A)
 0.82A 1fweC-2ogjA:
18.9		 1fweC-2ogjA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		3 / 3 ALA A 389
VAL A 100
TRP A  73
 None
 0.84A 1jnoA-2ogjA:
undetectable		 1jnoA-2ogjA:
3.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		3 / 3 ALA A 389
VAL A 100
TRP A  73
 None
 0.84A 1jnoB-2ogjA:
undetectable		 1jnoB-2ogjA:
3.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		3 / 3 ALA A 389
VAL A 100
TRP A  73
 None
 0.86A 1jo3A-2ogjA:
undetectable		 1jo3A-2ogjA:
3.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		3 / 3 ALA A 389
VAL A 100
TRP A  73
 None
 0.86A 1jo3B-2ogjA:
undetectable		 1jo3B-2ogjA:
3.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		3 / 3 ALA A 389
VAL A 100
TRP A  73
 None
 0.87A 1jo4A-2ogjA:
undetectable		 1jo4A-2ogjA:
3.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		3 / 3 ALA A 389
VAL A 100
TRP A  73
 None
 0.87A 1jo4B-2ogjA:
undetectable		 1jo4B-2ogjA:
3.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		3 / 3 ALA A 389
VAL A 100
TRP A  73
 None
 0.85A 1ng8A-2ogjA:
undetectable		 1ng8A-2ogjA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		3 / 3 ALA A 389
VAL A 100
TRP A  73
 None
 0.85A 1ng8B-2ogjA:
undetectable		 1ng8B-2ogjA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		3 / 3 ALA A 389
VAL A 100
TRP A  73
 None
 0.87A 1nruA-2ogjA:
undetectable		 1nruA-2ogjA:
3.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		3 / 3 ALA A 389
VAL A 100
TRP A  73
 None
 0.87A 1nruB-2ogjA:
undetectable		 1nruB-2ogjA:
3.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 12 THR A 326
ILE A 263
VAL A 301
PHE A 270
ALA A 305
 None
 1.31A 1vq1A-2ogjA:
undetectable		 1vq1A-2ogjA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		3 / 3 LYS A 176
ASP A 105
ASN A 134
 KCX  A 175 ( 3.5A)
None
KCX  A 175 ( 4.1A)
 0.93A 2bm9A-2ogjA:
undetectable		 2bm9A-2ogjA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		4 / 4 LEU A 140
SER A 179
ASP A 291
ASP A  75
 None
None
ZN  A 418 (-2.5A)
None
 1.27A 2br4B-2ogjA:
undetectable		 2br4B-2ogjA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		3 / 3 SER A 331
ASP A 262
CYH A 232
 None
 1.13A 2br4E-2ogjA:
undetectable		 2br4E-2ogjA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 9 THR A 362
ALA A 361
LEU A 311
LEU A 359
THR A 306
 None
 1.13A 2npnA-2ogjA:
undetectable		 2npnA-2ogjA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		3 / 3 LEU A 220
TYR A 216
GLY A 238
 None
 0.62A 2ocuA-2ogjA:
undetectable		 2ocuA-2ogjA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		3 / 3 LEU A 247
TYR A 216
GLY A 210
 None
 0.62A 2ocuA-2ogjA:
undetectable		 2ocuA-2ogjA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 12 PHE A 132
PRO A 329
THR A 102
VAL A  74
LEU A 304
 None
 1.02A 2xrlA-2ogjA:
undetectable		 2xrlA-2ogjA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 226
LEU A 223
VAL A 172
VAL A 104
PHE A 132
 None
 1.12A 2zulA-2ogjA:
undetectable		 2zulA-2ogjA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 12 PHE A 272
GLY A 366
PHE A 270
SER A 271
VAL A 301
 None
 1.36A 3dlcA-2ogjA:
undetectable		 3dlcA-2ogjA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		4 / 7 ASN A 144
ASP A 291
HIS A  77
HIS A 231
 None
ZN  A 418 (-2.5A)
KCX  A 175 (-3.3A)
ZN  A 419 (-3.6A)
 0.94A 3t01A-2ogjA:
undetectable		 3t01A-2ogjA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		4 / 7 ASN A 144
ASP A 291
ILE A  87
HIS A  79
 None
ZN  A 418 (-2.5A)
None
ZN  A 418 (-3.4A)
 0.92A 3t01A-2ogjA:
undetectable		 3t01A-2ogjA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		4 / 7 GLY A 187
ALA A 214
VAL A 209
ILE A 222
 None
 0.76A 3t3cA-2ogjA:
undetectable		 3t3cA-2ogjA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 11 VAL A 209
PHE A 233
SER A 240
PHE A 248
LEU A 247
 None
 1.24A 4eilA-2ogjA:
undetectable		 4eilA-2ogjA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 11 PHE A 233
SER A 240
PHE A 248
LEU A 247
VAL A 209
 None
 1.37A 4eilC-2ogjA:
undetectable		 4eilC-2ogjA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 11 VAL A 209
PHE A 233
SER A 240
PHE A 248
LEU A 247
 None
 1.24A 4eilC-2ogjA:
undetectable		 4eilC-2ogjA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 11 PHE A 233
SER A 240
PHE A 248
LEU A 247
VAL A 209
 None
 1.35A 4eilE-2ogjA:
undetectable		 4eilE-2ogjA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 11 VAL A 209
PHE A 233
SER A 240
PHE A 248
LEU A 247
 None
 1.26A 4eilE-2ogjA:
undetectable		 4eilE-2ogjA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_G_FOLG703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 10 VAL A 209
PHE A 233
SER A 240
PHE A 248
LEU A 247
 None
 1.29A 4eilG-2ogjA:
undetectable		 4eilG-2ogjA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		4 / 5 HIS A  77
HIS A 208
HIS A 231
ASP A 291
 KCX  A 175 (-3.3A)
ZN  A 419 (-3.4A)
ZN  A 419 (-3.6A)
ZN  A 418 (-2.5A)
 0.83A 4h9mA-2ogjA:
19.8		 4h9mA-2ogjA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_F_FOLF703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 12 PHE A 233
SER A 240
PHE A 248
LEU A 247
VAL A 209
 None
 1.46A 4kyaF-2ogjA:
undetectable		 4kyaF-2ogjA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 12 LEU A 335
VAL A  74
GLY A 264
ASP A 262
THR A 290
 None
 1.45A 4mubA-2ogjA:
undetectable		 4mubA-2ogjA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		4 / 7 ARG A 128
THR A 101
GLY A  72
THR A 102
 None
 0.95A 4qwpB-2ogjA:
undetectable		 4qwpB-2ogjA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 6 HIS A  77
HIS A  79
HIS A 208
HIS A 231
ASP A 291
 KCX  A 175 (-3.3A)
ZN  A 418 (-3.4A)
ZN  A 419 (-3.4A)
ZN  A 419 (-3.6A)
ZN  A 418 (-2.5A)
 0.71A 4ubpC-2ogjA:
18.5		 4ubpC-2ogjA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		4 / 5 PHE A 352
PRO A  24
VAL A  25
PHE A  27
 None
 1.20A 4w5oA-2ogjA:
undetectable		 4w5oA-2ogjA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		4 / 5 PHE A 352
PRO A  24
VAL A  25
PHE A  27
 None
 1.23A 4z4cA-2ogjA:
undetectable		 4z4cA-2ogjA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		4 / 5 PHE A 352
PRO A  24
VAL A  25
PHE A  27
 None
 1.22A 4z4dA-2ogjA:
2.1		 4z4dA-2ogjA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		4 / 5 PHE A 352
PRO A  24
VAL A  25
PHE A  27
 None
 1.22A 4z4eA-2ogjA:
undetectable		 4z4eA-2ogjA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		3 / 3 ARG A 281
ASN A 249
ASP A 217
 None
 0.85A 5gwxA-2ogjA:
undetectable		 5gwxA-2ogjA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_A_ASCA502_0
(OS09G0567300 PROTEIN)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		4 / 5 GLU A 148
PRO A 147
ARG A 177
ARG A 145
 None
 1.33A 5jcnA-2ogjA:
1.3		 5jcnA-2ogjA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		4 / 6 GLU A 148
PRO A 147
ARG A 177
ARG A 145
 None
 1.40A 5jcnB-2ogjA:
undetectable		 5jcnB-2ogjA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 12 LEU A 103
ASP A  75
THR A 290
GLY A 107
HIS A  79
 None
None
None
KCX  A 175 ( 4.0A)
ZN  A 418 (-3.4A)
 1.39A 5m66A-2ogjA:
undetectable		 5m66A-2ogjA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 12 LEU A 174
ARG A 177
GLY A 107
GLU A 148
GLY A 136
 KCX  A 175 ( 4.1A)
None
KCX  A 175 ( 4.0A)
None
None
 1.23A 5o4yD-2ogjA:
undetectable
5o4yE-2ogjA:
undetectable		 5o4yD-2ogjA:
2.84
5o4yE-2ogjA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 10 PHE A 233
ASP A 291
GLY A 266
PHE A 270
ALA A 106
 None
ZN  A 418 (-2.5A)
None
None
KCX  A 175 ( 3.6A)
 1.26A 5x66D-2ogjA:
undetectable		 5x66D-2ogjA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		5 / 10 PHE A 233
ILE A 263
GLY A 266
PHE A 270
ALA A 106
 None
None
None
None
KCX  A 175 ( 3.6A)
 1.37A 5x66D-2ogjA:
undetectable		 5x66D-2ogjA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		4 / 8 ASP A 156
ILE A 160
ARG A 159
ASN A 167
 None
 1.21A 6hisA-2ogjA:
undetectable
6hisB-2ogjA:
undetectable		 6hisA-2ogjA:
10.75
6hisB-2ogjA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		4 / 8 ASP A 156
ILE A 160
ARG A 159
ASN A 167
 None
 1.22A 6hisB-2ogjA:
undetectable
6hisC-2ogjA:
undetectable		 6hisB-2ogjA:
10.75
6hisC-2ogjA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 2ogj DIHYDROOROTASE
(Agrobacterium
fabrum) 		4 / 8 ASP A 156
ILE A 160
ARG A 159
ASN A 167
 None
 1.21A 6hisD-2ogjA:
undetectable
6hisE-2ogjA:
undetectable		 6hisD-2ogjA:
10.75
6hisE-2ogjA:
10.75