SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ogp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2ogp PARTITIONING-DEFECTI
VE 3 HOMOLOG
(Rattus
norvegicus) 		6 / 12 GLY A  30
ASP A  65
LEU A  68
GLY A  60
LEU A 105
LEU A  74
 None
 1.44A 2nxeA-2ogpA:
undetectable		 2nxeA-2ogpA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2ogp PARTITIONING-DEFECTI
VE 3 HOMOLOG
(Rattus
norvegicus) 		3 / 3 ALA A  70
ARG A 109
LYS A  21
 None
 0.90A 3kp5B-2ogpA:
undetectable		 3kp5B-2ogpA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ogp PARTITIONING-DEFECTI
VE 3 HOMOLOG
(Rattus
norvegicus) 		5 / 8 ARG A 109
LEU A  74
LEU A  27
ILE A  38
PHE A  36
 None
 1.43A 3ln1A-2ogpA:
undetectable		 3ln1A-2ogpA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ogp PARTITIONING-DEFECTI
VE 3 HOMOLOG
(Rattus
norvegicus) 		5 / 7 ARG A 109
LEU A  74
LEU A  27
ILE A  38
PHE A  36
 None
 1.44A 3ln1B-2ogpA:
undetectable		 3ln1B-2ogpA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 2ogp PARTITIONING-DEFECTI
VE 3 HOMOLOG
(Rattus
norvegicus) 		5 / 11 SER A  96
VAL A  90
LEU A  94
THR A  97
GLU A  76
 None
 1.01A 4e0fA-2ogpA:
undetectable		 4e0fA-2ogpA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2ogp PARTITIONING-DEFECTI
VE 3 HOMOLOG
(Rattus
norvegicus) 		4 / 6 LEU A  74
VAL A  77
LEU A  93
VAL A 103
 None
 0.98A 5x7zA-2ogpA:
undetectable		 5x7zA-2ogpA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 2ogp PARTITIONING-DEFECTI
VE 3 HOMOLOG
(Rattus
norvegicus) 		3 / 3 LEU A  57
ASP A  65
ILE A  25
 None
 0.65A 6dh0B-2ogpA:
undetectable		 6dh0B-2ogpA:
27.18