SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ogr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 2ogr FLUORESCENT PROTEIN
FP538
(Zoanthus
sp.) 		4 / 7 ALA A 223
TYR A  75
ILE A 224
PHE A 199
 None
 0.92A 1upfB-2ogrA:
undetectable		 1upfB-2ogrA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 2ogr FLUORESCENT PROTEIN
FP538
(Zoanthus
sp.) 		3 / 3 PHE A 126
PHE A  97
PHE A  99
 None
 0.53A 2od9A-2ogrA:
undetectable		 2od9A-2ogrA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 2ogr FLUORESCENT PROTEIN
FP538
(Zoanthus
sp.) 		3 / 3 PHE A 126
PHE A  97
PHE A  99
 None
 0.53A 2qqgA-2ogrA:
undetectable		 2qqgA-2ogrA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 2ogr FLUORESCENT PROTEIN
FP538
(Zoanthus
sp.) 		3 / 3 HIS A 222
GLU A 221
HIS A 202
 None
CH7  A  66 ( 3.6A)
CH7  A  66 ( 3.4A)
 0.83A 3ba0A-2ogrA:
undetectable		 3ba0A-2ogrA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2ogr FLUORESCENT PROTEIN
FP538
(Zoanthus
sp.) 		5 / 12 THR A 142
SER A  57
PHE A  99
ALA A 103
CYH A 105
 None
 1.18A 3u9fD-2ogrA:
undetectable
3u9fE-2ogrA:
undetectable		 3u9fD-2ogrA:
20.86
3u9fE-2ogrA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2ogr FLUORESCENT PROTEIN
FP538
(Zoanthus
sp.) 		5 / 12 THR A 142
TYR A 177
PHE A  99
ALA A 103
CYH A 105
 None
 1.08A 3u9fD-2ogrA:
undetectable
3u9fE-2ogrA:
undetectable		 3u9fD-2ogrA:
20.86
3u9fE-2ogrA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_G_CLMG221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2ogr FLUORESCENT PROTEIN
FP538
(Zoanthus
sp.) 		5 / 12 THR A 142
SER A  57
PHE A  99
ALA A 103
CYH A 105
 None
 1.22A 3u9fG-2ogrA:
undetectable
3u9fH-2ogrA:
undetectable		 3u9fG-2ogrA:
20.86
3u9fH-2ogrA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 2ogr FLUORESCENT PROTEIN
FP538
(Zoanthus
sp.) 		3 / 3 TYR A 168
MET A 167
ILE A 200
 None
CH7  A  66 ( 3.2A)
None
 0.67A 4c8bB-2ogrA:
undetectable		 4c8bB-2ogrA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 2ogr FLUORESCENT PROTEIN
FP538
(Zoanthus
sp.) 		3 / 3 PRO A 195
MET A 194
TYR A  82
 None
 0.78A 4qa0B-2ogrA:
undetectable		 4qa0B-2ogrA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 2ogr FLUORESCENT PROTEIN
FP538
(Zoanthus
sp.) 		3 / 3 PRO A 195
MET A 194
TYR A  82
 None
 0.78A 4qa0A-2ogrA:
undetectable		 4qa0A-2ogrA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 2ogr FLUORESCENT PROTEIN
FP538
(Zoanthus
sp.) 		3 / 3 PRO A 195
MET A 194
TYR A  82
 None
 0.86A 4qa2B-2ogrA:
undetectable		 4qa2B-2ogrA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 2ogr FLUORESCENT PROTEIN
FP538
(Zoanthus
sp.) 		5 / 12 ALA A  63
GLU A  58
LEU A  46
ILE A  29
PHE A  56
 CH7  A  66 ( 4.0A)
None
NFA  A  65 ( 4.4A)
NFA  A  65 ( 3.9A)
None
 0.99A 5vlmB-2ogrA:
undetectable		 5vlmB-2ogrA:
21.40