SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ogx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 12 PHE A 152
LEU A 101
ALA A 105
ALA A  80
ARG A  85
 None
None
None
ATP  A 281 (-3.6A)
ATP  A 281 (-4.2A)
 1.22A 1cbrA-2ogxA:
undetectable		 1cbrA-2ogxA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 12 PHE A 152
LEU A 101
ALA A 105
ALA A  80
ARG A  85
 None
None
None
ATP  A 281 (-3.6A)
ATP  A 281 (-4.2A)
 1.22A 1cbrB-2ogxA:
undetectable		 1cbrB-2ogxA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 12 LEU A 116
GLY A  79
ASN A 112
ALA A 109
ALA A 106
 None
ATP  A 281 (-3.2A)
None
None
W  A2015 (-4.2A)
 1.11A 2bm9C-2ogxA:
undetectable		 2bm9C-2ogxA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 12 GLY A 149
GLY A  48
ASN A 112
ALA A  80
ALA A 105
 None
ATP  A 281 (-3.8A)
None
ATP  A 281 (-3.6A)
None
 1.08A 2bm9F-2ogxA:
2.6		 2bm9F-2ogxA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 9 THR A 144
GLY A 124
LEU A 120
ALA A 146
LEU A 141
 None
 1.07A 2npnA-2ogxA:
2.5		 2npnA-2ogxA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 9 ASP A 171
ILE A  46
GLY A  48
VAL A 247
ILE A 188
 MG  A 291 ( 3.8A)
None
ATP  A 281 (-3.8A)
None
None
 1.30A 3ekyB-2ogxA:
undetectable		 3ekyB-2ogxA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		3 / 3 ARG A 169
ILE A 188
THR A 214
 None
 0.70A 3ia4D-2ogxA:
undetectable		 3ia4D-2ogxA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 10 ALA A 216
THR A 214
ILE A 195
VAL A 228
VAL A 247
 None
None
ATP  A 281 (-4.8A)
MG  A 291 ( 4.9A)
None
 1.06A 3me6A-2ogxA:
undetectable		 3me6A-2ogxA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 12 GLY A  79
GLY A  47
ALA A  84
ALA A 105
LEU A  77
 ATP  A 281 (-3.2A)
ATP  A 281 (-3.1A)
None
None
None
 0.94A 3mteB-2ogxA:
2.7		 3mteB-2ogxA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 12 GLY A  79
GLY A  47
ALA A  84
ALA A 105
LEU A  77
 ATP  A 281 (-3.2A)
ATP  A 281 (-3.1A)
None
None
None
 1.03A 3p2kA-2ogxA:
undetectable		 3p2kA-2ogxA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 12 GLY A  79
GLY A  47
ALA A  84
ALA A 105
LEU A  77
 ATP  A 281 (-3.2A)
ATP  A 281 (-3.1A)
None
None
None
 0.93A 3p2kC-2ogxA:
2.6		 3p2kC-2ogxA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 12 GLY A  79
GLY A  47
ALA A  84
ALA A 105
LEU A  77
 ATP  A 281 (-3.2A)
ATP  A 281 (-3.1A)
None
None
None
 1.02A 3p2kD-2ogxA:
2.6		 3p2kD-2ogxA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 12 GLY A  79
ILE A  46
ALA A  84
ARG A  85
ASP A  52
 ATP  A 281 (-3.2A)
None
None
ATP  A 281 (-4.2A)
None
 1.13A 4a6dA-2ogxA:
undetectable		 4a6dA-2ogxA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 10 GLY A 149
VAL A 128
VAL A 147
LEU A 177
LEU A 141
 None
 1.30A 4yb6A-2ogxA:
undetectable
4yb6E-2ogxA:
undetectable		 4yb6A-2ogxA:
22.82
4yb6E-2ogxA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 10 GLY A 149
VAL A 128
VAL A 147
LEU A 177
LEU A 141
 None
 1.30A 4yb6B-2ogxA:
undetectable
4yb6C-2ogxA:
undetectable		 4yb6B-2ogxA:
22.82
4yb6C-2ogxA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 10 LEU A 177
LEU A 141
GLY A 149
VAL A 128
VAL A 147
 None
 1.30A 4yb6B-2ogxA:
undetectable
4yb6F-2ogxA:
undetectable		 4yb6B-2ogxA:
22.82
4yb6F-2ogxA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_2
(CALCINEURIN SUBUNIT
B, VARIANT
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		4 / 4 LEU A  61
MET A  51
VAL A  50
ASN A 191
 None
None
None
ATP  A 281 (-2.8A)
 0.88A 5b8iB-2ogxA:
undetectable		 5b8iB-2ogxA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_2
(TUBULIN BETA-2B
CHAIN)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		3 / 3 LEU A  75
LEU A 141
ARG A  66
 None
 0.45A 5hnzB-2ogxA:
undetectable		 5hnzB-2ogxA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 9 THR A  78
GLY A  79
ALA A 151
GLY A  48
GLU A 190
 None
ATP  A 281 (-3.2A)
None
ATP  A 281 (-3.8A)
MG  A 291 ( 2.5A)
 1.13A 5vw4A-2ogxA:
3.3		 5vw4A-2ogxA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 8 THR A  78
GLY A  79
ALA A 151
GLY A  48
GLU A 190
 None
ATP  A 281 (-3.2A)
None
ATP  A 281 (-3.8A)
MG  A 291 ( 2.5A)
 1.07A 5vw9A-2ogxA:
undetectable		 5vw9A-2ogxA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 8 THR A  78
GLY A  79
ALA A 170
GLY A  48
GLU A 190
 None
ATP  A 281 (-3.2A)
ATP  A 281 ( 4.0A)
ATP  A 281 (-3.8A)
MG  A 291 ( 2.5A)
 1.30A 5vw9A-2ogxA:
undetectable		 5vw9A-2ogxA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 12 PRO A 154
ALA A  84
ARG A  85
PRO A 166
PHE A  88
 None
None
ATP  A 281 (-4.2A)
None
None
 1.28A 5zvgB-2ogxA:
undetectable		 5zvgB-2ogxA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_B_FJQB501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 11 ALA A 231
LEU A 232
ALA A 178
ALA A 151
LEU A 176
 None
 0.98A 6h1lB-2ogxA:
undetectable		 6h1lB-2ogxA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_B_FJQB501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 2ogx MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 11 ALA A 231
LEU A 232
VAL A 235
ALA A 178
ALA A 151
 None
 0.95A 6h1lB-2ogxA:
undetectable		 6h1lB-2ogxA:
19.82