SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oh1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 2oh1 ACETYLTRANSFERASE,
GNAT FAMILY
(Listeria
monocytogenes) 		5 / 8 ILE A   6
ILE A 124
ARG A  16
ILE A 117
VAL A  15
 None
 1.24A 2nniA-2oh1A:
undetectable		 2nniA-2oh1A:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2oh1 ACETYLTRANSFERASE,
GNAT FAMILY
(Listeria
monocytogenes) 		4 / 5 LEU A 150
ILE A 139
TRP A  94
TYR A 157
 None
None
None
EDO  A 181 (-4.7A)
 1.40A 2zlcA-2oh1A:
undetectable		 2zlcA-2oh1A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 2oh1 ACETYLTRANSFERASE,
GNAT FAMILY
(Listeria
monocytogenes) 		3 / 3 ASN A  27
LEU A  68
PHE A  52
 None
 0.74A 4dajB-2oh1A:
undetectable		 4dajB-2oh1A:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2oh1 ACETYLTRANSFERASE,
GNAT FAMILY
(Listeria
monocytogenes) 		5 / 12 TYR A 154
ILE A 144
ASN A 147
GLY A 167
SER A 162
 None
 1.14A 4obwC-2oh1A:
undetectable		 4obwC-2oh1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2oh1 ACETYLTRANSFERASE,
GNAT FAMILY
(Listeria
monocytogenes) 		4 / 5 ARG A  83
GLN A  59
ILE A  81
ASP A  53
 None
 1.30A 4z4hA-2oh1A:
undetectable		 4z4hA-2oh1A:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 2oh1 ACETYLTRANSFERASE,
GNAT FAMILY
(Listeria
monocytogenes) 		3 / 3 ASN A  27
LEU A  68
PHE A  52
 None
 0.71A 5dsgA-2oh1A:
undetectable		 5dsgA-2oh1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2oh1 ACETYLTRANSFERASE,
GNAT FAMILY
(Listeria
monocytogenes) 		5 / 9 ARG A  16
ALA A  79
VAL A  66
GLU A  70
ILE A  57
 None
 1.23A 5i3cA-2oh1A:
undetectable		 5i3cA-2oh1A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 2oh1 ACETYLTRANSFERASE,
GNAT FAMILY
(Listeria
monocytogenes) 		4 / 6 ARG A 107
THR A  33
ASP A  32
LEU A  29
 None
UNL  A 179 (-3.6A)
None
None
 1.10A 5tdzA-2oh1A:
undetectable		 5tdzA-2oh1A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 2oh1 ACETYLTRANSFERASE,
GNAT FAMILY
(Listeria
monocytogenes) 		5 / 10 ALA A  79
LEU A 119
GLU A  70
VAL A  15
ILE A   6
 None
 1.12A 5v02B-2oh1A:
undetectable
5v02R-2oh1A:
undetectable		 5v02B-2oh1A:
20.67
5v02R-2oh1A:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 2oh1 ACETYLTRANSFERASE,
GNAT FAMILY
(Listeria
monocytogenes) 		5 / 12 PHE A 114
ARG A  35
ILE A  26
GLY A  78
SER A 111
 None
None
None
None
UNL  A 179 (-4.7A)
 1.04A 6c2mA-2oh1A:
undetectable		 6c2mA-2oh1A:
19.19