SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oh3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_0
(DIHYDROFOLATE
REDUCTASE)		 2oh3 COG1633:
UNCHARACTERIZED
CONSERVED PROTEIN
(Magnetospirillum
magnetotacticum) 		5 / 12 ILE A  56
ALA A  14
LEU A  68
TYR A 111
THR A  17
 None
 1.15A 2w3bB-2oh3A:
undetectable		 2w3bB-2oh3A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_B_FOLB1188_0
(DIHYDROFOLATE
REDUCTASE)		 2oh3 COG1633:
UNCHARACTERIZED
CONSERVED PROTEIN
(Magnetospirillum
magnetotacticum) 		5 / 12 ILE A  56
ALA A  14
LEU A  68
TYR A 111
THR A  17
 None
 1.16A 2w3mB-2oh3A:
undetectable		 2w3mB-2oh3A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_D_TOPD1158_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 2oh3 COG1633:
UNCHARACTERIZED
CONSERVED PROTEIN
(Magnetospirillum
magnetotacticum) 		5 / 10 ILE A  56
ALA A  14
LEU A  68
TYR A 111
THR A  17
 None
 1.13A 2w9sD-2oh3A:
undetectable		 2w9sD-2oh3A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_F_TOPF1159_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 2oh3 COG1633:
UNCHARACTERIZED
CONSERVED PROTEIN
(Magnetospirillum
magnetotacticum) 		5 / 10 ILE A  56
ALA A  14
LEU A  68
TYR A 111
THR A  17
 None
 1.14A 2w9sF-2oh3A:
undetectable		 2w9sF-2oh3A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G8Z_X_TOPX301_1
(DIHYDROFOLATE
REDUCTASE)		 2oh3 COG1633:
UNCHARACTERIZED
CONSERVED PROTEIN
(Magnetospirillum
magnetotacticum) 		5 / 10 ILE A  56
ALA A  14
LEU A  68
TYR A 111
THR A  17
 None
 1.20A 4g8zX-2oh3A:
undetectable		 4g8zX-2oh3A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 2oh3 COG1633:
UNCHARACTERIZED
CONSERVED PROTEIN
(Magnetospirillum
magnetotacticum) 		4 / 6 TYR A 111
HIS A  52
GLU A  55
ARG A  59
 None
 1.37A 4zbqA-2oh3A:
undetectable		 4zbqA-2oh3A:
16.37