SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ohd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2ohd PROBABLE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
C
(Sulfurisphaera
tokodaii) 		5 / 10 THR A  91
ALA A 104
LEU A  16
VAL A  15
ILE A 144
 None
 1.13A 1claA-2ohdA:
undetectable		 1claA-2ohdA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 2ohd PROBABLE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
C
(Sulfurisphaera
tokodaii) 		4 / 7 THR A  60
VAL A 100
VAL A  21
VAL A 140
 None
 0.97A 2qbnA-2ohdA:
undetectable		 2qbnA-2ohdA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 2ohd PROBABLE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
C
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A 115
THR A 114
VAL A  45
ILE A  46
ILE A  79
 None
 1.19A 2yzqA-2ohdA:
undetectable		 2yzqA-2ohdA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 2ohd PROBABLE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
C
(Sulfurisphaera
tokodaii) 		4 / 7 SER A  90
LYS A  58
LEU A  55
ALA A  57
 None
 1.02A 3cfqA-2ohdA:
undetectable
3cfqB-2ohdA:
undetectable		 3cfqA-2ohdA:
19.73
3cfqB-2ohdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2ohd PROBABLE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
C
(Sulfurisphaera
tokodaii) 		4 / 8 ILE A 138
LEU A 112
ILE A  89
GLY A  85
 None
 0.85A 4hb8A-2ohdA:
undetectable		 4hb8A-2ohdA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2ohd PROBABLE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
C
(Sulfurisphaera
tokodaii) 		4 / 5 TYR A 122
GLY A  43
ASP A  44
VAL A  88
 None
 0.87A 4nkvD-2ohdA:
undetectable		 4nkvD-2ohdA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 2ohd PROBABLE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
C
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A  46
LEU A  86
GLY A  53
ALA A 111
LEU A 112
 None
 1.24A 5zwrA-2ohdA:
undetectable		 5zwrA-2ohdA:
17.05