SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ohh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 8 TRP A 152
TYR A  25
SER A 232
HIS A  83
 None
None
FE  A 501 ( 3.8A)
None
 0.82A 1ax9A-2ohhA:
undetectable		 1ax9A-2ohhA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 5 ASP A 170
HIS A 233
HIS A  83
HIS A  88
 FE  A 501 ( 2.3A)
FE  A 501 (-3.2A)
None
FE  A 501 (-3.1A)
 1.01A 1ei6A-2ohhA:
undetectable		 1ei6A-2ohhA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 TYR A 105
LEU A 142
LEU A 135
HIS A  88
LEU A  48
 None
None
None
FE  A 501 (-3.1A)
None
 1.25A 1fmlA-2ohhA:
undetectable		 1fmlA-2ohhA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 TYR A 105
LEU A 142
LEU A 135
HIS A  88
LEU A  48
 None
None
None
FE  A 501 (-3.1A)
None
 1.25A 1fmlB-2ohhA:
undetectable		 1fmlB-2ohhA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 8 TRP A 152
TYR A  25
SER A 232
HIS A  83
 None
None
FE  A 501 ( 3.8A)
None
 1.05A 1maaD-2ohhA:
undetectable		 1maaD-2ohhA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 LEU A 336
ILE A 301
LEU A 329
ILE A 311
THR A 341
 None
 1.19A 1re7B-2ohhA:
3.0		 1re7B-2ohhA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 6 PHE A  99
VAL A  76
LEU A  39
SER A  52
 None
 0.97A 1wrlB-2ohhA:
undetectable		 1wrlB-2ohhA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 ASN A  36
TRP A  14
GLN A 174
 None
 1.29A 1xoqA-2ohhA:
undetectable		 1xoqA-2ohhA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 5 ILE A   8
ILE A  80
MET A 228
LEU A  60
 None
 0.79A 1zgyA-2ohhA:
undetectable		 1zgyA-2ohhA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 7 TRP A 152
TYR A  25
SER A 232
HIS A  83
 None
None
FE  A 501 ( 3.8A)
None
 0.83A 2ackA-2ohhA:
undetectable		 2ackA-2ohhA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 8 LEU A 142
VAL A  12
LEU A  39
VAL A  76
 None
 1.03A 2bdmA-2ohhA:
undetectable		 2bdmA-2ohhA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 HIS A  26
HIS A  88
GLU A  85
HIS A  83
HIS A 175
 None
FE  A 501 (-3.1A)
FE  A 502 ( 2.9A)
None
None
 1.43A 2c6nB-2ohhA:
undetectable		 2c6nB-2ohhA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 5 VAL A  91
LEU A  95
MET A 156
ARG A  63
 None
 1.02A 2oiqA-2ohhA:
undetectable		 2oiqA-2ohhA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 8 ASP A  87
ASP A 170
LEU A 202
HIS A 233
 FE  A 501 (-2.9A)
FE  A 501 ( 2.3A)
None
FE  A 501 (-3.2A)
 0.76A 2q0iA-2ohhA:
19.4		 2q0iA-2ohhA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		5 / 11 ASP A  87
HIS A  88
ASP A 170
LEU A 202
HIS A 233
 FE  A 501 (-2.9A)
FE  A 501 (-3.1A)
FE  A 501 ( 2.3A)
None
FE  A 501 (-3.2A)
 0.80A 2q0jB-2ohhA:
19.6		 2q0jB-2ohhA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 5 LEU A 333
ARG A 344
ALA A 369
ILE A 311
 None
 0.93A 2qhfA-2ohhA:
undetectable		 2qhfA-2ohhA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 PHE A 167
ALA A 230
THR A  15
TYR A  13
LEU A  48
 None
 1.39A 2rctA-2ohhA:
undetectable		 2rctA-2ohhA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 6 LEU A 333
LEU A 336
ILE A 311
ARG A 344
 None
 0.93A 2rlfB-2ohhA:
undetectable
2rlfC-2ohhA:
undetectable		 2rlfB-2ohhA:
8.44
2rlfC-2ohhA:
8.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 6 LEU A 142
PHE A 167
LEU A 166
ASP A 163
 None
 1.09A 2wm3A-2ohhA:
7.5		 2wm3A-2ohhA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 7 VAL A 261
ILE A 277
ALA A 281
VAL A 288
 None
 0.80A 2xrzB-2ohhA:
undetectable		 2xrzB-2ohhA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 THR A 359
PRO A 322
THR A 361
 None
 0.91A 316dC-2ohhA:
undetectable		 316dC-2ohhA:
3.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_C_SRYC403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 ASP A 154
SER A 155
SER A 232
ASP A 170
TYR A 118
 None
None
FE  A 501 ( 3.8A)
FE  A 501 ( 2.3A)
None
 1.33A 3havC-2ohhA:
0.0		 3havC-2ohhA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 ASP A 154
LEU A  92
ILE A 104
ASP A 170
SER A 232
 None
None
None
FE  A 501 ( 2.3A)
FE  A 501 ( 3.8A)
 1.31A 3ko0G-2ohhA:
undetectable
3ko0H-2ohhA:
undetectable
3ko0I-2ohhA:
undetectable
3ko0J-2ohhA:
undetectable		 3ko0G-2ohhA:
13.40
3ko0H-2ohhA:
13.40
3ko0I-2ohhA:
13.40
3ko0J-2ohhA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 7 GLU A 279
HIS A 275
VAL A 288
ALA A 281
 None
 0.89A 3kp6B-2ohhA:
undetectable		 3kp6B-2ohhA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA309_1
(BETA-LACTAMASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 5 ILE A 165
ARG A 184
THR A 238
GLU A 185
 None
 1.48A 3ny4A-2ohhA:
undetectable		 3ny4A-2ohhA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		5 / 11 LEU A 160
LEU A  39
GLY A  11
ILE A  49
GLY A  42
 None
 1.14A 3zosA-2ohhA:
undetectable
3zosB-2ohhA:
undetectable		 3zosA-2ohhA:
21.63
3zosB-2ohhA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 5 LEU A 330
ILE A 305
ALA A 369
PHE A 371
 None
 0.90A 4dc3B-2ohhA:
5.5		 4dc3B-2ohhA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 8 LEU A  48
ALA A  37
LEU A  39
VAL A  17
 None
 0.86A 4iizB-2ohhA:
undetectable		 4iizB-2ohhA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 PHE A 167
ALA A 230
THR A  15
TYR A  13
LEU A  48
 None
 1.36A 4qynA-2ohhA:
undetectable		 4qynA-2ohhA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		4 / 7 ALA A 312
GLY A 280
ALA A 281
GLU A 284
 None
 0.86A 4r1zB-2ohhA:
undetectable		 4r1zB-2ohhA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		5 / 10 GLY A  45
GLY A 138
LEU A 137
LEU A 160
GLU A 162
 None
 0.99A 5hwkA-2ohhA:
undetectable		 5hwkA-2ohhA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		5 / 10 GLY A  45
GLY A 138
LEU A 137
LEU A 160
GLU A 162
 None
 0.98A 5hwkB-2ohhA:
undetectable		 5hwkB-2ohhA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		5 / 11 ASN A  24
SER A 299
THR A  29
TYR A 332
LEU A 333
 None
 1.34A 5jh7B-2ohhA:
4.8		 5jh7B-2ohhA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		5 / 11 ASN A  24
VAL A 302
SER A 299
TYR A 332
LEU A 333
 None
 1.26A 5jh7B-2ohhA:
4.8		 5jh7B-2ohhA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 GLY A 314
GLY A 350
VAL A 326
VAL A 261
LEU A 313
 None
 1.20A 5kocB-2ohhA:
undetectable		 5kocB-2ohhA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 HIS A  83
ASP A 170
HIS A 233
 None
FE  A 501 ( 2.3A)
FE  A 501 (-3.2A)
 0.75A 5oexB-2ohhA:
undetectable		 5oexB-2ohhA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 HIS A  83
ASP A 170
HIS A 233
 None
FE  A 501 ( 2.3A)
FE  A 501 (-3.2A)
 0.73A 5oexC-2ohhA:
undetectable		 5oexC-2ohhA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 HIS A  83
ASP A 170
HIS A 233
 None
FE  A 501 ( 2.3A)
FE  A 501 (-3.2A)
 0.73A 5oexD-2ohhA:
undetectable		 5oexD-2ohhA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 ARG A 258
LYS A 303
TYR A 291
 None
 1.36A 6gnaA-2ohhA:
5.1		 6gnaA-2ohhA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 ARG A 258
LYS A 303
TYR A 291
 None
 1.36A 6gnbA-2ohhA:
5.1		 6gnbA-2ohhA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)		 2ohh TYPE A FLAVOPROTEIN
FPRA
(Methanothermobac
ter
thermautotrophic
us) 		5 / 11 HIS A  88
ASP A 170
LEU A  30
HIS A 175
SER A 232
 FE  A 501 (-3.1A)
FE  A 501 ( 2.3A)
None
None
FE  A 501 ( 3.8A)
 1.20A 6ieyA-2ohhA:
4.4
6ieyB-2ohhA:
4.4		 6ieyA-2ohhA:
22.55
6ieyB-2ohhA:
22.55