SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ohw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LM8_C_VIBC223_1 (THIAMINE PYROPHOSPHOKINASE)	2ohw	YUEI PROTEIN (Bacillus subtilis)	4 / 8	LYS A 3 ASP A 7 LEU A 27 LEU A 10	None	0.96A	3lm8A-2ohwA: undetectable 3lm8C-2ohwA: undetectable	3lm8A-2ohwA: 19.63 3lm8C-2ohwA: 19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EYR_B_RITB301_1 (HIV-1 PROTEASE)	2ohw	YUEI PROTEIN (Bacillus subtilis)	4 / 7	LEU A 29 ALA A 39 ILE A 124 THR A 101	None	0.91A	4eyrA-2ohwA: undetectable	4eyrA-2ohwA: 22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XJE_A_TOYA202_1 (AADB)	2ohw	YUEI PROTEIN (Bacillus subtilis)	4 / 8	ASP A 123 TYR A 51 ASP A 122 GLU A 53	None	0.79A	4xjeA-2ohwA: undetectable	4xjeA-2ohwA: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CFS_A_TOYA203_1 (AAD(2''),GENTAMICIN 2''-NUCLEOTIDYLTRANS FERASE,GENTAMICIN RESISTANCE PROTEIN)	2ohw	YUEI PROTEIN (Bacillus subtilis)	4 / 8	ASP A 123 TYR A 51 ASP A 122 GLU A 53	None	0.87A	5cfsA-2ohwA: undetectable	5cfsA-2ohwA: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_A_CVIA301_0 (REGULATORY PROTEIN TETR)	2ohw	YUEI PROTEIN (Bacillus subtilis)	5 / 12	GLN A 44 GLU A 57 LEU A 40 ILE A 105 TYR A 74	None	1.36A	5vlmA-2ohwA: undetectable	5vlmA-2ohwA: 21.32

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3LM8_C_VIBC223_1","THIAMINE PYROPHOSPHOKINASE;THIAMINE PYROPHOSPHOKINASE","2ohw","YUEI PROTEIN","Bacillus subtilis",4,"LYS A   3;ASP A   7;LEU A  27;LEU A  10","None","0.96A","3lm8A-2ohwA:undetectable;3lm8C-2ohwA:undetectable","3lm8A-2ohwA:19.63;3lm8C-2ohwA:19.63"],["4EYR_B_RITB301_1","HIV-1 PROTEASE;HIV-1 PROTEASE","2ohw","YUEI PROTEIN","Bacillus subtilis",4,"LEU A  29;ALA A  39;ILE A 124;THR A 101","None","0.91A","4eyrA-2ohwA:undetectable","4eyrA-2ohwA:22.06"],["4XJE_A_TOYA202_1","AADB","2ohw","YUEI PROTEIN","Bacillus subtilis",4,"ASP A 123;TYR A  51;ASP A 122;GLU A  53","None","0.79A","4xjeA-2ohwA:undetectable","4xjeA-2ohwA:19.90"],["5CFS_A_TOYA203_1","AAD(2''),GENTAMICIN 2''-NUCLEOTIDYLTRANSFERASE,GENTAMICIN RESISTANCE PROTEIN","2ohw","YUEI PROTEIN","Bacillus subtilis",4,"ASP A 123;TYR A  51;ASP A 122;GLU A  53","None","0.87A","5cfsA-2ohwA:undetectable","5cfsA-2ohwA:19.90"],["5VLM_A_CVIA301_0","REGULATORY PROTEIN TETR","2ohw","YUEI PROTEIN","Bacillus subtilis",5,"GLN A  44;GLU A  57;LEU A  40;ILE A 105;TYR A  74","None","1.36A","5vlmA-2ohwA:undetectable","5vlmA-2ohwA:21.32"]]